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The traditional approach used to implement a business process (BP) in today's information systems (IS) no longer covers the actual needs of the dynamically changing business. Therefore, a necessity for a new approach of dynamic business…

Software Engineering · Computer Science 2018-07-11 Olegas Vasilecas , Diana Kalibatiene , Dejan Lavbič

Seamless model based development aims to use models during all phases of the development process of a system. During the development process in a component-based approach, components of a system are described at qualitatively differing…

Software Engineering · Computer Science 2012-02-29 Jan Olaf Blech , Dongyue Mou , Daniel Ratiu

Model-based experimental design is attracting increasing attention in chemical process engineering. Typically, an iterative procedure is pursued: an approximate model is devised, prescribed experiments are then performed and the resulting…

Optimization and Control · Mathematics 2021-01-25 Charlie Vanaret , Philipp Seufert , Jan Schwientek , Gleb Karpov , Gleb Ryzhakov , Ivan Oseledets , Norbert Asprion , Michael Bortz

In large-scale projects operated in regulated environments, standard development processes are employed to meet strict compliance demands. Since such processes are usually complex, providing process users with access to their required…

Software Engineering · Computer Science 2025-02-18 Oliver Greulich , Christoph Knieke , Bassel Rafie , Andreas Rausch , Marco Kuhrmann

Business process (BP) analysis represents a first key phase of information system development. It consists in the gathering of domain knowledge and its organization to be later used in the software development, and beyond (e.g., for…

Software Engineering · Computer Science 2022-01-19 Michele Missikoff

In manufacturing sectors such as textiles and electronics, manual processes are a fundamental part of production. The analysis and monitoring of the processes is necessary for efficient production design. Traditional methods for analyzing…

Computer Vision and Pattern Recognition · Computer Science 2023-10-13 Marlin Berger , Frederik Cloppenburg , Jens Eufinger , Thomas Gries

Molecular Dynamics (MD) simulations are fundamental computational tools for the study of proteins and their free energy landscapes. However, sampling protein conformational changes through MD simulations is challenging due to the relatively…

Biomolecules · Quantitative Biology 2023-07-20 Diego E. Kleiman , Hassan Nadeem , Diwakar Shukla

Plant breeding programs use data obtained from multi-environment selection experiments to produce improved varieties with the ultimate aim of maintaining high levels of genetic gain. Selection accuracy can be improved with the use of…

Methodology · Statistics 2026-05-13 Brian R Cullis , Alison B Smith , David GD Hughes , David Butler

Domain-specific constraint patterns are introduced, which form the counterpart to design patterns in software engineering for the constraint programming setting. These patterns describe the expert knowledge and best-practice solution to…

Software Engineering · Computer Science 2022-06-07 Sophia Saller , Jana Koehler

Dataset Distillation (DD), a newly emerging field, aims at generating much smaller but efficient synthetic training datasets from large ones. Existing DD methods based on gradient matching achieve leading performance; however, they are…

Machine Learning · Computer Science 2023-04-18 Lei Zhang , Jie Zhang , Bowen Lei , Subhabrata Mukherjee , Xiang Pan , Bo Zhao , Caiwen Ding , Yao Li , Dongkuan Xu

We demonstrate the application of the Dynamic Mode Decomposition (DMD) for the diagnostic analysis of the nonlinear dynamics of a magnetized plasma in resistive magnetohydrodynamics. The DMD method is an ideal spatio-temporal matrix…

Plasma Physics · Physics 2018-05-23 Roy Taylor , J. Nathan Kutz , Kyle Morgan , Brian Nelson

This paper discusses a model-based approach to software development. It argues that an approach using models as central development artifact needs to be added to the portfolio of software engineering techniques, to further increase…

Software Engineering · Computer Science 2014-09-25 Bernhard Rumpe

We present a novel computational paradigm for process design in manufacturing processes that incorporates simulation responses to optimize manufacturing process parameters in high-dimensional temporal and spatial design spaces. We developed…

Computational Engineering, Finance, and Science · Computer Science 2021-07-26 Mojtaba Mozaffar , Jian Cao

For economic nonlinear model predictive control and dynamic real-time optimization fast and accurate models are necessary. Consequently, the use of dynamic surrogate models to mimic complex rigorous models is increasingly coming into focus.…

Systems and Control · Electrical Eng. & Systems 2021-07-30 Torben Talis , Joris Weigert , Erik Esche , Jens-Uwe Repke

Sampling-based algorithms are widely used for motion planning in high-dimensional configuration spaces. However, due to low sampling efficiency, their performance often diminishes in complex configuration spaces with narrow corridors.…

Robotics · Computer Science 2025-07-22 Lu Huang , Lingxiao Meng , Jiankun Wang , Xingjian Jing

The success of diffusion models has driven interest in performing conditional sampling via training-free guidance of the denoising process to solve image restoration and other inverse problems. A popular class of methods, based on Diffusion…

Machine Learning · Statistics 2025-06-17 Gregory Bellchambers

An approach is introduced, which supports a testing technician in the identification of possibly untested behavior of control software of fully integrated automated production systems (aPS). Based on an approach for guided semi-automatic…

Software Engineering · Computer Science 2022-12-12 Sebastian Ulewicz , Birgit Vogel-Heuser

In our daily lives and industrial settings, we often encounter dynamic problems that require reasoning over time and metric constraints. These include tasks such as scheduling, routing, and production sequencing. Dynamic logics have…

Artificial Intelligence · Computer Science 2025-02-14 Susana Hahn

We present a Quality by Design (QbD) styled approach for optimizing lipid nanoparticle (LNP) formulations, aiming to offer scientists an accessible workflow. The inherent restriction in these studies, where the molar ratios of ionizable,…

Applications · Statistics 2023-11-14 Andrew T. Karl , Sean Essex , James Wisnowski , Heath Rushing

Scientific software is often driven by multiple parameters that affect both accuracy and performance. Since finding the optimal configuration of these parameters is a highly complex task, it extremely common that the software is used…

Computational Engineering, Finance, and Science · Computer Science 2016-08-17 Diego Fabregat-Traver , Ahmed E. Ismail , Paolo Bientinesi