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Developing new drugs is laborious and costly, demanding extensive time investment. In this paper, we introduce a de-novo drug design strategy, which harnesses the capabilities of language models to devise targeted drugs for specific…

Biomolecules · Quantitative Biology 2025-05-20 Salma J. Ahmed , Emad A. Mohammed

Reinforcement learning (RL) has been widely used in text generation to alleviate the exposure bias issue or to utilize non-parallel datasets. The reward function plays an important role in making RL training successful. However, previous…

Machine Learning · Computer Science 2023-01-19 Yongchang Hao , Yuxin Liu , Lili Mou

Retrieval-augmented generation (RAG) improves knowledge-intensive question answering by incorporating external evidence. However, existing RAG methods still suffer from hallucinations and subtle reasoning errors. Recent studies introduce…

Computation and Language · Computer Science 2026-05-29 Wenhan Xiao , Ziwei Zhang , Chuanyue Yu , Xingcheng Fu , Qingyun Sun , Runhua Xu , Jianxin Li

As generative models become ubiquitous, there is a critical need for fine-grained control over the generation process. Yet, while controlled generation methods from prompting to fine-tuning proliferate, a fundamental question remains…

Artificial Intelligence · Computer Science 2026-01-12 Emily Cheng , Carmen Amo Alonso , Federico Danieli , Arno Blaas , Luca Zappella , Pau Rodriguez , Xavier Suau

Automatic evaluation of text generation is essential for improving the accuracy of generation tasks. In light of the current trend towards increasingly larger decoder-based language models, we investigate automatic evaluation methods based…

Computation and Language · Computer Science 2023-10-18 Tomohito Kasahara , Daisuke Kawahara

In this paper, we propose a novel controllable text-to-image generative adversarial network (ControlGAN), which can effectively synthesise high-quality images and also control parts of the image generation according to natural language…

Computer Vision and Pattern Recognition · Computer Science 2019-12-20 Bowen Li , Xiaojuan Qi , Thomas Lukasiewicz , Philip H. S. Torr

Composing poetry or lyrics involves several creative factors, but a challenging aspect of generation is the adherence to a more or less strict metric and rhyming pattern. To address this challenge specifically, previous work on the task has…

Computation and Language · Computer Science 2024-05-09 Tommaso Pasini , Alejo López-Ávila , Husam Quteineh , Gerasimos Lampouras , Jinhua Du , Yubing Wang , Ze Li , Yusen Sun

Transformer-based language models have shown to be very powerful for natural language generation (NLG). However, text generation conditioned on some user inputs, such as topics or attributes, is non-trivial. Past approach relies on either…

Computation and Language · Computer Science 2020-11-17 Fan-Keng Sun , Cheng-I Lai

Prior work on controllable text generation usually assumes that the controlled attribute can take on one of a small set of values known a priori. In this work, we propose a novel task, where the syntax of a generated sentence is controlled…

Computation and Language · Computer Science 2019-06-04 Mingda Chen , Qingming Tang , Sam Wiseman , Kevin Gimpel

Large Language Models (LLMs) have revolutionised the field of Natural Language Processing (NLP) and have achieved state-of-the-art performance in practically every task in this field. However, the prevalent approach used in text generation,…

Computation and Language · Computer Science 2024-08-12 Nicolo Micheletti , Samuel Belkadi , Lifeng Han , Goran Nenadic

In-hand manipulation and grasping are fundamental yet often separately addressed tasks in robotics. For deriving in-hand manipulation policies, reinforcement learning has recently shown great success. However, the derived controllers are…

Robotics · Computer Science 2025-09-16 Lennart Röstel , Dominik Winkelbauer , Johannes Pitz , Leon Sievers , Berthold Bäuml

We demonstrate that Contrastive Decoding -- a simple, computationally light, and training-free text generation method proposed by Li et al 2022 -- achieves large out-of-the-box improvements over greedy decoding on a variety of reasoning…

Computation and Language · Computer Science 2023-10-02 Sean O'Brien , Mike Lewis

Neural text generation models conditioning on given input (e.g. machine translation and image captioning) are usually trained by maximum likelihood estimation of target text. However, the trained models suffer from various types of errors…

Computation and Language · Computer Science 2020-12-29 Keisuke Shirai , Kazuma Hashimoto , Akiko Eriguchi , Takashi Ninomiya , Shinsuke Mori

Flow-based generative models have shown remarkable success in text-to-image generation, yet fine-tuning them with intermediate feedback remains challenging, especially for continuous-time flow matching models. Most existing approaches…

Machine Learning · Computer Science 2025-10-22 Jiajun Fan , Chaoran Cheng , Shuaike Shen , Xiangxin Zhou , Ge Liu

The advances in unsupervised object-centric representation learning have significantly improved its application to downstream tasks. Recent works highlight that disentangled object representations can aid policy learning in image-based,…

Artificial Intelligence · Computer Science 2025-03-21 Leonid Ugadiarov , Vitaliy Vorobyov , Aleksandr I. Panov

Modern generative pre-trained language models excel at open-ended text generation, yet continue to underperform on structure-related tasks such as NER, relation extraction, and semantic role labeling, especially when compared to…

Computation and Language · Computer Science 2025-12-23 Minho Lee , Junghyun Min , Yerang Kim , Woochul Lee , Yeonsoo Lee

The most common training pipeline for large language models includes pretraining, finetuning and aligning phases, with their respective resulting models, such as the pretrained model and the finetuned model. Finetuned and aligned models…

Computation and Language · Computer Science 2024-02-29 Lifeng Jin , Baolin Peng , Linfeng Song , Haitao Mi , Ye Tian , Dong Yu

Data availability is a bottleneck during early stages of development of new capabilities for intelligent artificial agents. We investigate the use of text generation techniques to augment the training data of a popular commercial artificial…

Computation and Language · Computer Science 2019-10-09 Nikolaos Malandrakis , Minmin Shen , Anuj Goyal , Shuyang Gao , Abhishek Sethi , Angeliki Metallinou

Aligning language models (LMs) with user intent is becoming increasingly relevant to enhance user experience. This calls for designing methods that can allow users to control the properties of the language that LMs generate, for example,…

Computation and Language · Computer Science 2025-09-23 Vinay Samuel , Harshita Diddee , Yiming Zhang , Daphne Ippolito

Large language models (LLMs) have recently transformed from text-based assistants to autonomous agents capable of planning, reasoning, and iteratively improving their actions. While numerical reward signals and verifiers can effectively…

Computation and Language · Computer Science 2025-10-28 Ruihan Yang , Fanghua Ye , Jian Li , Siyu Yuan , Yikai Zhang , Zhaopeng Tu , Xiaolong Li , Deqing Yang