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Fourier ptychographic microscopy (FPM) is a recently developed computational imaging technique for wide-field, high-resolution microscopy with a high space-bandwidth product. It integrates the concepts of synthetic aperture and phase…
Fluorescent molecules are versatile nanoscale emitters that enable detailed observations of biophysical processes with nanoscale resolution. Because they are well-approximated as electric dipoles, imaging systems can be designed to…
Fluorescence microscopy is a powerful tool for imaging biological samples with molecular specificity. In contrast, phase microscopy provides label-free measurement of the sample's refractive index (RI), which is an intrinsic optical…
Metasurfaces provide a compact, flexible, and reliable solution for controlling the wavefront of light. In imaging systems, micro-lens arrays are integrated with pixel matrices to reduce optical crosstalk, enhance photon collection…
We report on a new x-ray imaging method, which combines the high spatial resolution of coherent diffraction imaging with the ability of dark field microscopy to map grains within thick polycrystalline specimens. An x-ray objective serves to…
High efficiency collection of photons emitted by a point source over a wide field-of-view (FoV) is crucial for many applications. Multi-scale optics over improved light collection by utilizing small optical components placed close to the…
Interferometry provides one of the possible routes to ultra-high angular resolution for X-ray and gamma-ray astronomy. Sub-micro-arc-second angular resolution, necessary to achieve objectives such as imaging the regions around the event…
Metalenses, in order to compete with conventional bulk optics in commercial imaging systems, often require large field of view (FOV) and broadband operation simultaneously. However, strong chromatic and coma aberrations present in common…
Temporal focusing two-photon microscopy enables high resolution imaging of fine structures in vivo over a large volume. A limitation of temporal focusing is that signal-to-background ratio and resolution degrade rapidly with increasing…
Accurate characterization of the inner surface of X-ray monocapillary optics (XMCO) is of great significance in X-ray optics research. Compared with other characterization methods, the micro computed tomography (micro-CT) method has its…
Dark-field x-ray microscopy utilizes Bragg diffraction to collect full-field x-ray images of "mesoscale" structure of ordered materials. Information regarding the structural heterogeneities and their physical implications is gleaned through…
Macro x-ray fluorescence (XRF) imaging of cultural heritage objects, while a popular non-invasive technique for providing elemental distribution maps, is a slow acquisition process in acquiring high signal-to-noise ratio XRF volumes.…
The back-focal plane (BFP) of a high-numerical aperture objective contains the fluoro-phore radiation pattern, which encodes information about the axial fluorophore position, molecular orientation and the local refractive index of the…
An integrated microscope that combines different optical techniques for simultaneous imaging is demonstrated. The microscope enables spectral-domain optical coherence microscopy based on optical backscatter, and multi-photon microscopy for…
In coherent X-ray diffraction microscopy the diffraction pattern generated by a sample illuminated with coherent x-rays is recorded, and a computer algorithm recovers the unmeasured phases to synthesize an image. By avoiding the use of a…
The spatial resolution achieved by recent synchrotron radiation microtomographs should be estimated from the modulation transfer function (MTF) on the micrometer scale. Step response functions of a synchrotron radiation microtomograph were…
The main challenges posed by the design of future Positron Emission Tomography machines are the improvement of the spatial and timing resolution and the combined operation with magnetic resonance. The Micro Pixel Photon Counter by Hamamatsu…
A comprehensive investigation of the signal-to-noise ratio (SNR) of the microwave photonic filter (MPF) with an interferometric structure based on an incoherent broadband optical source (IBOS) is presented from the time and frequency…
Ongoing advances in scanning probe microscopy techniques are continually expanding the possibilities for nanoscale characterization and correlated studies of functional materials. Here, we demonstrate how a recent extension of piezoresponse…
In the process of performing image super-resolution processing, the processing of complex localized information can have a significant impact on the quality of the image generated. Fractal features can capture the rich details of both micro…