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Anticancer peptides (ACPs) are a class of molecules that have gained significant attention in the field of cancer research and therapy. ACPs are short chains of amino acids, the building blocks of proteins, and they possess the ability to…

Biomolecules · Quantitative Biology 2024-01-05 Zeynep Hilal Kilimci , Mustafa Yalcin

Anticancer peptides (ACPs) are a group of peptides that exhibite antineoplastic properties. The utilization of ACPs in cancer prevention can present a viable substitute for conventional cancer therapeutics, as they possess a higher degree…

Machine Learning · Computer Science 2023-09-22 Onur Karakaya , Zeynep Hilal Kilimci

Cancer is a complex disease characterized by uncontrolled cell growth and proliferation. T cell receptors (TCRs) are essential proteins for the adaptive immune system, and their specific recognition of antigens plays a crucial role in the…

Machine Learning · Computer Science 2023-09-07 Zahra Tayebi , Sarwan Ali , Prakash Chourasia , Taslim Murad , Murray Patterson

In this paper, we propose sparse coding-based approaches for segmentation of tumor regions from MR images. Sparse coding with data-adapted dictionaries has been successfully employed in several image recovery and vision problems. The…

Computer Vision and Pattern Recognition · Computer Science 2013-03-12 Jayaraman J. Thiagarajan , Karthikeyan Natesan Ramamurthy , Deepta Rajan , Anup Puri , David Frakes , Andreas Spanias

In recent years, kernel-based sparse coding (K-SRC) has received particular attention due to its efficient representation of nonlinear data structures in the feature space. Nevertheless, the existing K-SRC methods suffer from the lack of…

Machine Learning · Computer Science 2019-03-14 Babak Hosseini , Barbara Hammer

Sparse representation based classification (SRC) methods have achieved remarkable results. SRC, however, still suffer from requiring enough training samples, insufficient use of test samples and instability of representation. In this paper,…

Quantitative Methods · Quantitative Biology 2019-06-28 Xiao-Hui Yang , Li Tian , Yun-Mei Chen , Li-Jun Yang , Shuang Xu , Wen-Ming Wu

Due to its promising classification performance, sparse representation based classification(SRC) algorithm has attracted great attention in the past few years. However, the existing SRC type methods apply only to vector data in Euclidean…

Computer Vision and Pattern Recognition · Computer Science 2016-01-28 Ming Yin , Shengli Xie , Yi Guo , Junbin Gao , Yun Zhang

In this paper, a novel framework of sparse kernel learning for Support Vector Data Description (SVDD) based anomaly detection is presented. In this work, optimal sparse feature selection for anomaly detection is first modeled as a Mixed…

Machine Learning · Computer Science 2015-06-09 Zhimin Peng , Prudhvi Gurram , Heesung Kwon , Wotao Yin

In this paper, we propose a new method to perform Sparse Kernel Principal Component Analysis (SKPCA) and also mathematically analyze the validity of SKPCA. We formulate SKPCA as a constrained optimization problem with elastic net…

Machine Learning · Computer Science 2018-09-17 Rudrajit Das , Aditya Golatkar , Suyash P. Awate

Semi-supervised learning (SSL) has attracted considerable attention in medical image processing. The latest SSL methods use a combination of consistency regularization and pseudo-labeling to achieve remarkable success. However, most…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Qiangguo Jin , Hui Cui , Junbo Wang , Changming Sun , Yimiao He , Ping Xuan , Linlin Wang , Cong Cong , Leyi Wei , Ran Su

Species living in the extreme cold environment fight against the harsh conditions using antifreeze proteins (AFPs), that manipulates the freezing mechanism of water in more than one way. This amazing nature of AFP turns out to be extremely…

Computer Vision and Pattern Recognition · Computer Science 2021-09-27 Shujaat Khan , Muhammad Usman , Abdul Wahab

An improved version of the sparse multiway kernel spectral clustering (KSC) is presented in this brief. The original algorithm is derived from weighted kernel principal component (KPCA) analysis formulated within the primal-dual…

Machine Learning · Computer Science 2023-10-23 Mihaly Novak , Rocco Langone , Carlos Alzate , Johan Suykens

Principal Component Analysis (PCA) has been used to study the pathogenesis of diseases. To enhance the interpretability of classical PCA, various improved PCA methods have been proposed to date. Among these, a typical method is the…

Machine Learning · Computer Science 2019-05-29 Chun-Mei Feng , Yong Xu , Jin-Xing Liu , Ying-Lian Gao , Chun-Hou Zheng

In complex visual recognition tasks it is typical to adopt multiple descriptors, that describe different aspects of the images, for obtaining an improved recognition performance. Descriptors that have diverse forms can be fused into a…

Computer Vision and Pattern Recognition · Computer Science 2015-06-15 Jayaraman J. Thiagarajan , Karthikeyan Natesan Ramamurthy , Andreas Spanias

Breast cancer is the most common cancer among women both in developed and developing countries. Early detection and diagnosis of breast cancer may reduce its mortality and improve the quality of life. Computer-aided detection (CADx) and…

Image and Video Processing · Electrical Eng. & Systems 2020-11-23 Sokratis Makrogiannis , Chelsea E. Harris , Keni Zheng

Microarray gene expression data-based tumor classification is an active and challenging issue. In this paper, an integrated tumor classification framework is presented, which aims to exploit information in existing available samples, and…

Computer Vision and Pattern Recognition · Computer Science 2019-03-01 Xiaohui Yang , Wenming Wu , Yunmei Chen , Xianqi Li , Juan Zhang , Dan Long , Lijun Yang

Sparse learning has been shown to be effective in solving many real-world problems. Finding sparse representations is a fundamentally important topic in many fields of science including signal processing, computer vision, genome study and…

Computer Vision and Pattern Recognition · Computer Science 2018-07-30 Jun Cheng

Due to the complexity of cancer, clustering algorithms have been used to disentangle the observed heterogeneity and identify cancer subtypes that can be treated specifically. While kernel based clustering approaches allow the use of more…

Machine Learning · Statistics 2018-11-21 Nora K. Speicher , Nico Pfeifer

Sparse representation-based classification (SRC), proposed by Wright et al., seeks the sparsest decomposition of a test sample over the dictionary of training samples, with classification to the most-contributing class. Because it assumes…

Computer Vision and Pattern Recognition · Computer Science 2018-06-05 Chelsea Weaver , Naoki Saito

Cell recognition is a fundamental task in digital histopathology image analysis. Point-based cell recognition (PCR) methods normally require a vast number of annotations, which is extremely costly, time-consuming and labor-intensive.…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Zhongyi Shui , Yizhi Zhao , Sunyi Zheng , Yunlong Zhang , Honglin Li , Shichuan Zhang , Xiaoxuan Yu , Chenglu Zhu , Lin Yang
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