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Over 300 million people worldwide are affected by various retinal diseases. By noninvasive Optical Coherence Tomography (OCT) scans, a number of abnormal structural changes in the retina, namely retinal lesions, can be identified. Automated…

Computer Vision and Pattern Recognition · Computer Science 2022-04-26 Yue Wu , Yang Zhou , Jianchun Zhao , Jingyuan Yang , Weihong Yu , Youxin Chen , Xirong Li

Macular Holes, Central serous retinopathy and Diabetic Retinopathy are one of the most widespread maladies of the eyes responsible for either partial or complete vision loss, thus making it clear that early detection of the mentioned…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Shashwat Jha , Vishvaditya Luhach , Raju Poddar

Purpose: This study explores the feasibility of using generative machine learning (ML) to translate Optical Coherence Tomography (OCT) images into Optical Coherence Tomography Angiography (OCTA) images, potentially bypassing the need for…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Rashadul Hasan Badhon , Atalie Carina Thompson , Jennifer I. Lim , Theodore Leng , Minhaj Nur Alam

Optical coherence tomography (OCT) scanning is useful in detecting various retinal diseases. However, there are not enough ophthalmologists who can diagnose retinal OCT images in much of the world. To provide OCT screening inexpensively and…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Ayaka Suzuki , Yoshiro Suzuki

Reliable automated analysis of Optical Coherence Tomography (OCT) imaging is crucial for diagnosing retinal disorders but faces a critical barrier: the need for expensive, labor-intensive expert annotations. Supervised deep learning models…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Tania Haghighi , Sina Gholami , Hamed Tabkhi , Minhaj Nur Alam

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Optical coherence tomography (OCT) has revolutionized retinal disease diagnosis with its high-resolution and three-dimensional imaging nature, yet its full diagnostic automation in clinical practices remains constrained by multi-stage…

Currently, diagnosis of skin diseases is based primarily on visual pattern recognition skills and expertise of the physician observing the lesion. Even though dermatologists are trained to recognize patterns of morphology, it is still a…

Optical Coherence Tomography (OCT) is a non-invasive depth resolved optical imaging modality, that enables high resolution, cross-sectional imaging in biological tissues and materials at clinically relevant depths. Though OCT offers high…

Medical Physics · Physics 2020-05-29 Cerine Lal , Sergey Alexandrov , Sweta Rani , Yi Zhou , Thomas Ritter , Martin Leahy

Optical coherence tomography (OCT) uses low-coherence reflectometry to obtain cross-sectional images of inhomogeneous media, such as biological tissue. OCT is particularly useful in the biomedical ea, since the imaging can be performed…

Medical Physics · Physics 2018-03-01 Takahisa Mitsui , Kenichiro Aoki

Quantification of intra-retinal boundaries in optical coherence tomography (OCT) is a crucial task for studying and diagnosing neurological and ocular diseases. Since manual segmentation of layers is usually a time consuming task and relay…

Computer Vision and Pattern Recognition · Computer Science 2015-02-17 Mahdi Salarian

Optical coherence tomography angiography (OCTA) is a novel noninvasive imaging modality for visualization of retinal blood flow in the human retina. Using specific OCTA imaging biomarkers for the identification of pathologies, automated…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Anna Breger , Felix Goldbach , Bianca S. Gerendas , Ursula Schmidt-Erfurth , Martin Ehler

In medical science, the use of computer science in disease detection and diagnosis is gaining popularity. Previously, the detection of disease used to take a significant amount of time and was less reliable. Machine learning (ML) techniques…

Image and Video Processing · Electrical Eng. & Systems 2019-12-18 Nowshin Tasnim , Mahmudul Hasan , Ishrak Islam

Optical Coherence Tomography (OCT) has become an indispensable tool for investigating mesoscopic features in soft matter and fluid mechanics. Its ability to provide high-resolution, non-invasive measurements in both spatial and temporal…

Recent Alzheimer's disease (AD) patient studies have focused on retinal analysis, as the retina is the only part of the central nervous system which can be imaged non-invasively by optical methods. However as this is a relatively new…

Optical Coherence Tomography (OCT) provides high-resolution cross-sectional images useful for diagnosing various diseases, but their distinct characteristics from natural images raise questions about whether large-scale pre-training on…

Computer Vision and Pattern Recognition · Computer Science 2025-02-19 Zihao Han , Philippe De Wilde

Recent studies suggest that early stages of diabetic retinopathy (DR) can be diagnosed by monitoring vascular changes in the deep vascular complex. In this work, we investigate a novel method for automated DR grading based on optical…

Image and Video Processing · Electrical Eng. & Systems 2022-12-22 Linus Kreitner , Ivan Ezhov , Daniel Rueckert , Johannes C. Paetzold , Martin J. Menten

The unique vascularized anatomy of the human eye, encased in the retina, provides an opportunity to act as a window for human health. The retinal structure assists in assessing the early detection, monitoring of disease progression and…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Inamullah , Imran Razzak , Shoaib Jameel

30 million Optical Coherence Tomography (OCT) imaging tests are issued annually to diagnose various retinal diseases, but accurate diagnosis of OCT scans requires trained eye care professionals who are still prone to making errors. With…

Image and Video Processing · Electrical Eng. & Systems 2022-10-04 Evan Wen , Rebecca Sorenson , Max Ehrlich

Optical coherence tomography angiography (OCTA) is a non-invasive imaging technique widely used to study vascular structures and micro-circulation dynamics in the retina and choroid. OCTA has been widely used in clinics for diagnosing…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Kejie Chen , Guanbing Gao , Xiaochun Yang , Wenbo Wang , Jing Na