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Generative molecular design has moved from proof-of-concept to real-world applicability, as marked by the surge in very recent papers reporting experimental validation. Key challenges in explainability and sample efficiency present…

Biomolecules · Quantitative Biology 2024-03-05 Jeff Guo , Philippe Schwaller

We consider the system-wide utility maximization problem in the downlink of a cell-free massive multiple-input multiple-output (MIMO) system whereby a very large number of access points (APs) simultaneously serve a group of users.…

Signal Processing · Electrical Eng. & Systems 2020-09-22 Muhammad Farooq , Hien Quoc Ngo , Een-Kee Hong , Le-Nam Tran

Existing approaches to automatic summarization assume that a length limit for the summary is given, and view content selection as an optimization problem to maximize informativeness and minimize redundancy within this budget. This framework…

Computation and Language · Computer Science 2019-01-15 Jingyun Liu , Jackie C. K. Cheung , Annie Louis

Machine learning methods are increasingly employed to address challenges faced by biologists. One area that will greatly benefit from this cross-pollination is the problem of biological sequence design, which has massive potential for…

Quantitative Methods · Quantitative Biology 2020-10-26 Sam Sinai , Eric D Kelsic

Large-scale multiobjective optimization problems (LSMOPs) refer to optimization problems with multiple conflicting optimization objectives and hundreds or even thousands of decision variables. A key point in solving LSMOPs is how to balance…

Neural and Evolutionary Computing · Computer Science 2023-04-17 Haokai Hong , Min Jiang , Liang Feng , Qiuzhen Lin , Kay Chen Tan

The explosive growth of IoT-enabled sensors is producing enormous amounts of time series data across many domains, offering valuable opportunities to extract insights through temporal pattern mining. Among these patterns, an important class…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-18 Van Ho-Long , Nguyen Ho , Anh-Vu Dinh-Duc , Ha Manh Tran , Ky Trung Nguyen , Tran Dung Pham , Quoc Viet Hung Nguyen

Sequence classification algorithms, such as SVM, require a definition of distance (similarity) measure between two sequences. A commonly used notion of similarity is the number of matches between $k$-mers ($k$-length subsequences) in the…

Data Structures and Algorithms · Computer Science 2017-12-13 Muhammad Farhan , Juvaria Tariq , Arif Zaman , Mudassir Shabbir , Imdad Ullah Khan

We consider the problem of utility optimal scheduling in general \emph{processing networks} with random arrivals and network conditions. These are generalizations of traditional data networks where commodities in one or more queues can be…

Optimization and Control · Mathematics 2010-10-12 Longbo Huang , Michael J. Neely

We investigate the application of classification techniques to utility elicitation. In a decision problem, two sets of parameters must generally be elicited: the probabilities and the utilities. While the prior and conditional probabilities…

Artificial Intelligence · Computer Science 2013-02-01 Urszula Chajewska , Lise Getoor , Joseph Norman , Yuval Shahar

In this work, we address unconstrained finite-sum optimization problems, with particular focus on instances originating in large scale deep learning scenarios. Our main interest lies in the exploration of the relationship between recent…

Optimization and Control · Mathematics 2026-03-13 Matteo Lapucci , Davide Pucci

In sequence to sequence learning, the self-attention mechanism proves to be highly effective, and achieves significant improvements in many tasks. However, the self-attention mechanism is not without its own flaws. Although self-attention…

Computation and Language · Computer Science 2019-11-22 Guangxiang Zhao , Xu Sun , Jingjing Xu , Zhiyuan Zhang , Liangchen Luo

There have been many recent studies on sequential pattern mining. The sequential pattern mining on progressive databases is relatively very new, in which we progressively discover the sequential patterns in period of interest. Period of…

Databases · Computer Science 2010-07-15 B. N. Keshavamurthy , Mitesh Sharma , Durga Toshniwal

We introduce a linear space of finitely additive measures to treat the problem of optimal expected utility from consumption under a stochastic clock and an unbounded random endowment process. In this way we establish existence and…

Probability · Mathematics 2008-12-10 Gordan Zitkovic

In the rapidly evolving research on artificial intelligence (AI) the demand for fast, computationally efficient, and scalable solutions has increased in recent years. The problem of optimizing the computing resources for distributed machine…

Machine Learning · Computer Science 2025-10-30 Mohammadreza Doostmohammadian , Zulfiya R. Gabidullina , Hamid R. Rabiee

Given limited and costly computational infrastructure, resource efficiency is a key requirement for large language models (LLMs). Efficient LLMs increase service capacity for providers and reduce latency and API costs for users. Recent…

Cryptography and Security · Computer Science 2026-04-14 Yuanhe Zhang , Xinyue Wang , Zhican Chen , Weiliu Wang , Zilu Zhang , Zhengshuo Gong , Zhenhong Zhou , Kun Wang , Li Sun , Yang Liu , Sen Su

Rich user behavior data has been proven to be of great value for click-through rate prediction tasks, especially in industrial applications such as recommender systems and online advertising. Both industry and academy have paid much…

Information Retrieval · Computer Science 2020-06-30 Pi Qi , Xiaoqiang Zhu , Guorui Zhou , Yujing Zhang , Zhe Wang , Lejian Ren , Ying Fan , Kun Gai

Sequence optimization, where the items in a list are ordered to maximize some reward has many applications such as web advertisement placement, search, and control libraries in robotics. Previous work in sequence optimization produces a…

Artificial Intelligence · Computer Science 2012-02-10 Debadeepta Dey , Tian Yu Liu , Martial Hebert , J. Andrew Bagnell

Sequential recommendation systems alleviate the problem of information overload, and have attracted increasing attention in the literature. Most prior works usually obtain an overall representation based on the user's behavior sequence,…

Information Retrieval · Computer Science 2022-08-12 Gaode Chen , Xinghua Zhang , Yanyan Zhao , Cong Xue , Ji Xiang

In this paper we study a robust utility maximization problem in continuous time under model uncertainty. The model uncertainty is governed by a continuous semimartingale with uncertain local characteristics. Here, the differential…

Mathematical Finance · Quantitative Finance 2023-08-04 David Criens , Lars Niemann

This article presents a new methodology for extracting intervals when a home is vacant from low-frequency electricity consumption data. The approach combines multiple algorithms, including change point detection, classification, period…

Machine Learning · Computer Science 2023-12-15 Thomas Brilland , Guillaume Matheron , Laetitia Leduc , Yukihide Nakada