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Confocal microscopy is the standard approach for obtaining volumetric images of a sample with high axial and lateral resolution, especially when dealing with scattering samples. Unfortunately, a confocal microscope is quite expensive…

The ability to experimentally map the three-dimensional structure and dynamics in bulk and patterned three-dimensional ferromagnets is essential both for understanding fundamental micromagnetic processes, as well as for investigating…

Optical diffraction tomography (ODT) is a three-dimensional (3D) label-free imaging technique. The 3D refractive index distribution of a sample can be reconstructed from multiple two-dimensional optical field images via ODT. Herein, we…

Optics · Physics 2021-02-03 Chansuk Park , Kyeoreh Lee , Yoonseok Baek , Yongkeun Park

Third harmonic generation (THG) provides a valuable, label-free approach to imaging biological systems. To date, THG microscopy has been performed using point scanning methods that rely on intensity measurements lacking phase information of…

Super-resolution fluorescence microscopy provides unprecedented insight into cellular and subcellular structures. However, going "beyond the diffraction barrier" comes at a price since most far-field super-resolution imaging techniques…

Optically-detected magnetic resonance using Nitrogen Vacancy (NV) color centres in diamond is a leading modality for nanoscale magnetic field imaging, as it provides single electron spin sensitivity, three-dimensional resolution better than…

Mesoscale and Nanoscale Physics · Physics 2015-10-28 K. Arai , C. Belthangady , H. Zhang , N. Bar-Gill , S. J. DeVience , P. Cappellaro , A. Yacoby , R. L. Walsworth

Inline holographic imaging presents an ill-posed inverse problem of reconstructing objects' complex amplitude from recorded diffraction patterns. Although recent deep learning approaches have shown promise over classical phase retrieval…

Optics · Physics 2025-07-02 Chanseok Lee , Fakhriyya Mammadova , Jiseong Barg , Mooseok Jang

Label-free microscopy exploits light scattering to obtain a three-dimensional image of biological tissues. However, light propagation is affected by aberrations and multiple scattering, which drastically degrade the image quality and limit…

Holography is capable of rendering three-dimensional scenes with full-depth control, and delivering transformative experiences across numerous domains, including virtual and augmented reality, education, and communication. However,…

Optics · Physics 2024-09-12 Zhenxing Dong , Yuye Ling , Yan Li , Yikai Su

Computer-Generated Holography (CGH) offers the potential for genuine, high-quality three-dimensional visuals. However, fulfilling this potential remains a practical challenge due to computational complexity and visual quality issues. We…

To recover the three dimensional (3D) volumetric distribution of matter in an object, images of the object are captured from multiple directions and locations. Using these images tomographic computations extract the distribution. In highly…

Computer Vision and Pattern Recognition · Computer Science 2015-12-08 Vadim Holodovsky , Yoav Y. Schechner , Anat Levin , Aviad Levis , Amit Aides

Simultaneous imaging of fluorescence-labeled and label-free phase objects in the same sample provides distinct and complementary information. Most multimodal fluorescence-phase imaging operates in transmission mode, capturing fluorescence…

Optics · Physics 2024-08-20 Renzhi He , Yucheng Li , Junjie Chen , Yi Xue

Polarization in ferroelectric domains arises from atomic-scale structural variations that govern macroscopic functionalities. The interfaces between these domains known as domain walls host distinct physical responses, making their…

The 3D structure of light scattering from dark-field illuminated live 3T3 cells marked with 40 nm gold nanomarkers is explored. For this purpose, we use a high resolution holographic microscope combining the off-axis heterodyne geometry and…

Our proposed method of random phase-free holography using virtual convergence light can obtain large reconstructed images exceeding the size of the hologram, without the assistance of random phase. The reconstructed images have low-speckle…

We derive a new 3D model for magnetic particle imaging (MPI) that is able to incorporate realistic magnetic fields in the reconstruction process. In real MPI scanners, the generated magnetic fields have distortions that lead to deformed…

Numerical Analysis · Mathematics 2020-12-30 Gaël Bringout , Wolfgang Erb , Jürgen Frikel

A new method for reconstruction of coronal magnetic fields as force-free fields (FFFs) is presented. Our method employs poloidal and toroidal functions to describe divergence-free magnetic fields. This magnetic field representation…

Solar and Stellar Astrophysics · Physics 2022-10-04 Sibaek Yi , G. S. Choe , Kyung-Suk Cho , Sami K. Solanki , Jörg Büchner

Magnetic resonance (MR) imaging relies on conventional electronics that is increasingly challenged by the push for stronger magnetic fields and higher channel count. These problems can be avoided by utilizing optical technologies. As a…

Organoids are three-dimensional (3D) in vitro models for studying tissue development, disease progression, and physiological responses. Holotomography (HT) enables long-term, label-free imaging of live organoids by reconstructing volumetric…

Medical Physics · Physics 2025-12-30 ChulMin Oh , Jimin Cho , Juyeon Park , Hoyeon Lee , YongKeun Park

We demonstrate a novel approach to the reconstruction of scanning probe x-ray diffraction tomography data with anisotropic poly crystalline samples. The method involves reconstructing a voxel map containing an orientation distribution…