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Deep learning has become a powerful tool in computational biology, revolutionising the analysis and interpretation of biological data over time. In our article review, we delve into various aspects of deep learning in computational biology.…

Early diagnosis of interstitial lung diseases is crucial for their treatment, but even experienced physicians find it difficult, as their clinical manifestations are similar. In order to assist with the diagnosis, computer-aided diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2016-12-13 Stergios Christodoulidis , Marios Anthimopoulos , Lukas Ebner , Andreas Christe , Stavroula Mougiakakou

In this paper, we examine the strength of deep learning technique for diagnosing lung cancer on medical image analysis problem. Convolutional neural networks (CNNs) models become popular among the pattern recognition and computer vision…

Computer Vision and Pattern Recognition · Computer Science 2018-04-24 Mehdi Fatan Serj , Bahram Lavi , Gabriela Hoff , Domenec Puig Valls

Cells are the fundamental unit of biological organization, and identifying them in imaging data - cell segmentation - is a critical task for various cellular imaging experiments. While deep learning methods have led to substantial progress…

Efficient processing of large-scale time series data is an intricate problem in machine learning. Conventional sensor signal processing pipelines with hand engineered feature extraction often involve huge computational cost with high…

We apply recent advances in deep generative modeling to the task of imitation learning from biological agents. Specifically, we apply variations of the variational recurrent neural network model to a multi-agent setting where we learn…

Machine Learning · Computer Science 2020-07-02 Michael Teng , Tuan Anh Le , Adam Scibior , Frank Wood

Nowadays, machine and deep learning techniques are widely used in different areas, ranging from economics to biology. In general, these techniques can be used in two ways: trying to adapt well-known models and architectures to the available…

Machine Learning · Computer Science 2022-03-21 Danilo Avola , Marco Cascio , Luigi Cinque , Alessio Fagioli , Gian Luca Foresti , Marco Raoul Marini , Daniele Pannone

As a fundamental challenge in vast disciplines, link prediction aims to identify potential links in a network based on the incomplete observed information, which has broad applications ranging from uncovering missing protein-protein…

Social and Information Networks · Computer Science 2017-05-08 Hao Liao , Mingyang Zhou , Zong-Wen Wei , Rui Mao , Alexandre Vidmer , Yi-Cheng Zhang

Studying cell morphology changes in time is critical to understanding cell migration mechanisms. In this work, we present a deep learning-based workflow to segment cancer cells embedded in 3D collagen matrices and imaged with phase-contrast…

Computer Vision and Pattern Recognition · Computer Science 2021-12-17 Estibaliz Gómez-de-Mariscal , Hasini Jayatilaka , Özgün Çiçek , Thomas Brox , Denis Wirtz , Arrate Muñoz-Barrutia

In order to better model complex real-world data such as multiphase flow, one approach is to develop pattern recognition techniques and robust features that capture the relevant information. In this paper, we use deep learning methods, and…

Machine Learning · Computer Science 2017-05-23 Mohammadmehdi Ezzatabadipour , Parth Singh , Melvin D. Robinson , Pablo Guillen-Rondon , Carlos Torres

We present a novel approach for learning to predict sets using deep learning. In recent years, deep neural networks have shown remarkable results in computer vision, natural language processing and other related problems. Despite their…

Computer Vision and Pattern Recognition · Computer Science 2017-11-23 S. Hamid Rezatofighi , Anton Milan , Qinfeng Shi , Anthony Dick , Ian Reid

Systematic relations between multiple objects that occur in various fields can be represented as networks. Real-world networks typically exhibit complex topologies whose structural properties are key factors in characterizing and further…

Physics and Society · Physics 2021-04-09 Yoshihisa Tanaka , Ryosuke Kojima , Shoichi Ishida , Fumiyoshi Yamashita , Yasushi Okuno

Counting cells in fluorescent microscopy is a tedious, time-consuming task that researchers have to accomplish to assess the effects of different experimental conditions on biological structures of interest. Although such objects are…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 R. Morelli , L. Clissa , M. Dalla , M. Luppi , L. Rinaldi , A. Zoccoli

In a recurrent setting, conventional approaches to neural architecture search find and fix a general model for all data samples and time steps. We propose a novel algorithm that can dynamically search for the structure of cells in a…

Machine Learning · Computer Science 2019-05-28 Xin Qian , Matthew Kennedy , Diego Klabjan

Vision foundation models trained on discretely sampled images achieve strong performance on classification benchmarks, yet whether their representations encode the continuous processes underlying their training data remains unclear. This…

Computer Vision and Pattern Recognition · Computer Science 2026-01-30 Pritika Vig , Ren-Chin Wu , William Lotter

Cell segmentation is a major bottleneck in extracting quantitative single-cell information from microscopy data. The challenge is exasperated in the setting of microstructured environments. While deep learning approaches have proven useful…

Quantitative Methods · Quantitative Biology 2021-01-08 Tim Prangemeier , Christian Wildner , André O. Françani , Christoph Reich , Heinz Koeppl

Molecular and morphological characters, as important parts of biological taxonomy, are contradictory but need to be integrated. Organism's image recognition and bioinformatics are emerging and hot problems nowadays but with a gap between…

Computer Vision and Pattern Recognition · Computer Science 2022-06-29 Jiewen Xiao , Wenbin Liao , Ming Zhang , Jing Wang , Jianxin Wang , Yihua Yang

Cell fate decisions emerge as a consequence of a complex set of gene regulatory networks. Models of these networks are known to have more parameters than data can determine. Recent work, inspired by Waddington's metaphor of a landscape, has…

Quantitative Methods · Quantitative Biology 2023-05-08 Archishman Raju , Eric D. Siggia

Image-based sequencing of mRNA makes it possible to see where in a tissue sample a given gene is active, and thus discern large numbers of different cell types in parallel. This is crucial for gaining a better understanding of tissue…

Quantitative Methods · Quantitative Biology 2018-02-27 Gabriele Partel , Giorgia Milli , Carolina Wählby

We present a method combining affinity prediction with region agglomeration, which improves significantly upon the state of the art of neuron segmentation from electron microscopy (EM) in accuracy and scalability. Our method consists of a…

Computer Vision and Pattern Recognition · Computer Science 2020-07-29 Jan Funke , Fabian David Tschopp , William Grisaitis , Arlo Sheridan , Chandan Singh , Stephan Saalfeld , Srinivas C. Turaga
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