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We propose a formal model for counterfactual estimation with unobserved confounding in "data-rich" settings, i.e., where there are a large number of units and a large number of measurements per unit. Our model provides a bridge between the…

Econometrics · Economics 2025-04-03 Alberto Abadie , Anish Agarwal , Devavrat Shah

The estimation of individual treatment effects (ITE) focuses on predicting the outcome changes that result from a change in treatment. A fundamental challenge in observational data is that while we need to infer outcome differences under…

Machine Learning · Computer Science 2025-12-23 Zichuan Lin , Xiaokai Huang , Jiate Liu , Yuxuan Han , Jia Chen , Xiapeng Wu , Deheng Ye

Recent advances in deep learning have improved multivariate time series (MTS) classification and regression by capturing complex patterns, but their lack of transparency hinders decision-making. Explainable AI (XAI) methods offer partial…

Machine Learning · Computer Science 2025-11-25 Alan G. Paredes Cetina , Kaouther Benguessoum , Raoni Lourenço , Sylvain Kubler

World models learn to predict the temporal evolution of visual observations given a control signal, potentially enabling agents to reason about environments through forward simulation. Because of the focus on forward simulation, current…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Yiqing Shen , Aiza Maksutova , Chenjia Li , Mathias Unberath

Causal analysis for time series data, in particular estimating individualized treatment effect (ITE), is a key task in many real-world applications, such as finance, retail, healthcare, etc. Real-world time series can include large-scale,…

Machine Learning · Computer Science 2023-03-07 Defu Cao , James Enouen , Yujing Wang , Xiangchen Song , Chuizheng Meng , Hao Niu , Yan Liu

Learning individual-level treatment effect is a fundamental problem in causal inference and has received increasing attention in many areas, especially in the user growth area which concerns many internet companies. Recently, disentangled…

Machine Learning · Computer Science 2022-06-03 Mingyuan Cheng , Xinru Liao , Quan Liu , Bin Ma , Jian Xu , Bo Zheng

We study counterfactual prediction under assignment bias and propose a mathematically grounded, information-theoretic approach that removes treatment-covariate dependence without adversarial training. Starting from a bound that links the…

Machine Learning · Computer Science 2026-04-28 Shiqin Tang , Rong Feng , Shuxin Zhuang , Youzhi Zhang , Hongzong Li

Understanding the effects of quarantine policies in populations with underlying social networks is crucial for public health, yet most causal inference methods fail here due to their assumption of independent individuals. We introduce…

Artificial Intelligence · Computer Science 2024-12-09 Suhan Guo , Furao Shen , Ni Li

Counterfactual explanations suggest what should be different in the input instance to change the outcome of an AI system. When dealing with counterfactual explanations in the field of Predictive Process Monitoring, however, control flow…

Artificial Intelligence · Computer Science 2025-08-26 Andrei Buliga , Chiara Di Francescomarino , Chiara Ghidini , Ivan Donadello , Fabrizio Maria Maggi

Marginal structural models are a popular tool for investigating the effects of time-varying treatments, but they require an assumption of no unobserved confounders between the treatment and outcome. With observational data, this assumption…

Methodology · Statistics 2021-06-10 Matthew Blackwell , Soichiro Yamauchi

While randomized controlled trials (RCTs) are the gold standard for estimating treatment effects in medical research, there is increasing use of and interest in using real-world data for drug development. One such use case is the…

Methodology · Statistics 2021-10-11 Devin Incerti , Michael T Bretscher , Ray Lin , Chris Harbron

AI-driven precision oncology has the transformative potential to reshape cancer treatment by leveraging the power of AI models to analyze the interaction between complex patient characteristics and their corresponding treatment outcomes.…

Estimating individualized treatment effects from longitudinal observational data is central to data-driven medicine, yet existing methods face a fundamental limitation: reducing confounding bias often suppresses clinically informative…

Randomized clinical trials (RCTs) are ideal for estimating causal effects, because the distributions of background covariates are similar in expectation across treatment groups. When estimating causal effects using observational data,…

Methodology · Statistics 2019-02-27 Anthony D. Scotina , Roee Gutman

Estimating heterogeneous treatment effects with machine learning has attracted substantial attention in both academic research and industrial practice. However, the two communities often evaluate models under markedly different conditions.…

Machine Learning · Computer Science 2026-05-26 George Panagopoulos

Often in follow-up studies intermediate events occur in some patients, such as reinterventions or adverse events. These intermediate events directly affect the shapes of their longitudinal profiles. Our work is motivated by two studies in…

Stress testing poses a causal question: how would portfolio credit losses change if the macroeconomy followed an adverse counterfactual path? Yet standard practice remains predictive and might be therefore vulnerable to omitted-variable…

Artificial Intelligence · Computer Science 2026-05-19 Yu Wang , Xiangchen Liu , Siguang Li

We propose a model-free framework for sensitivity analysis of individual treatment effects (ITEs), building upon ideas from conformal inference. For any unit, our procedure reports the $\Gamma$-value, a number which quantifies the minimum…

Methodology · Statistics 2022-04-26 Ying Jin , Zhimei Ren , Emmanuel J. Candès

Treatment effect estimation, which refers to the estimation of causal effects and aims to measure the strength of the causal relationship, is of great importance in many fields but is a challenging problem in practice. As present,…

Machine Learning · Computer Science 2021-07-20 Zhenyu Guo , Shuai Zheng , Zhizhe Liu , Kun Yan , Zhenfeng Zhu

In a wide variety of applications, including personalization, we want to measure the difference in outcome due to an intervention and thus have to deal with counterfactual inference. The feedback from a customer in any of these situations…

Artificial Intelligence · Computer Science 2018-08-24 Abhimanyu Mitra , Kannan Achan , Sushant Kumar
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