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High-dimensional penalized rank regression is a powerful tool for modeling high-dimensional data due to its robustness and estimation efficiency. However, the non-smoothness of the rank loss brings great challenges to the computation. To…

Methodology · Statistics 2025-02-20 Leheng Cai , Xu Guo , Heng Lian , Liping Zhu

We develop a continuous-time penalized regression framework for the estimation of time-varying coefficients and variable selection when both the response and covariates are It\^o semimartingales with jumps. The coefficient paths are…

Econometrics · Economics 2026-04-28 Aleksey Kolokolov , Shifan Yu

High-dimensional data often arise from clinical genomics research to infer relevant predictors of a particular trait. A way to improve the predictive performance is to include information on the predictors derived from prior knowledge or…

Methodology · Statistics 2023-03-13 Claudio Busatto , Mark van de Wiel

We propose a new causal inference framework to learn causal effects from multiple, decentralized data sources in a federated setting. We introduce an adaptive transfer algorithm that learns the similarities among the data sources by…

Machine Learning · Computer Science 2023-01-03 Thanh Vinh Vo , Arnab Bhattacharyya , Young Lee , Tze-Yun Leong

Incorporation of external information into high-dimensional modeling for gene expression data has been shown, both theoretically and empirically, to substantially enhance performance. Such external information, sometimes referred to as…

Methodology · Statistics 2026-04-17 Fuzhi Xu , Weijuan Liang , Shuangge Ma , Qingzhao Zhang

In many applications, data can be heterogeneous in the sense of spanning latent groups with different underlying distributions. When predictive models are applied to such data the heterogeneity can affect both predictive performance and…

Machine Learning · Statistics 2022-05-04 Thomas Lartigue , Sach Mukherjee

Clinical research often focuses on complex traits in which many variables play a role in mechanisms driving, or curing, diseases. Clinical prediction is hard when data is high-dimensional, but additional information, like domain knowledge…

Methodology · Statistics 2020-05-21 Mirrelijn M. van Nee , Lodewyk F. A. Wessels , Mark A. van de Wiel

We consider penalized regression models under a unified framework where the particular method is determined by the form of the penalty term. We propose a fully Bayesian approach that incorporates both sparse and dense settings and show how…

Methodology · Statistics 2019-07-25 Ding Xiang , Galin L. Jones

Penalized generalized estimating equations with Elastic Net or L2-Smoothly Clipped Absolute Deviation penalization are proposed to simultaneously select the most important variables and estimate their effects for longitudinal Gaussian data…

Methodology · Statistics 2012-11-26 Adriaan Blommaert , Niel Hens , Philippe Beutels

We consider a flexible semiparametric quantile regression model for analyzing high dimensional heterogeneous data. This model has several appealing features: (1) By considering different conditional quantiles, we may obtain a more complete…

Statistics Theory · Mathematics 2016-01-25 Ben Sherwood , Lan Wang

Parameter estimation and the variable selection are two pioneer issues in regression analysis. While traditional variable selection methods require prior estimation of the model parameters, the penalized methods simultaneously carry on…

Methodology · Statistics 2021-09-01 Yetkin Tuaç , Olcay Arslan

We introduce a new empirical Bayes approach for large-scale multiple linear regression. Our approach combines two key ideas: (i) the use of flexible "adaptive shrinkage" priors, which approximate the nonparametric family of scale mixture of…

Methodology · Statistics 2024-06-13 Youngseok Kim , Wei Wang , Peter Carbonetto , Matthew Stephens

In this paper, we consider the problem of learning a linear regression model on a data domain of interest (target) given few samples. To aid learning, we are provided with a set of pre-trained regression models that are trained on…

Machine Learning · Computer Science 2023-06-27 Navjot Singh , Suhas Diggavi

Estimating causal effects from high-dimensional, structured exposures is a fundamental challenge in modern applications ranging from neuroscience and finance to environmental science. While the literature has addressed high-dimensional…

Methodology · Statistics 2026-04-29 Samhita Pal , Dhrubajyoti Ghosh

Point process modeling is gaining increasing attention, as point process type data are emerging in numerous scientific applications. In this article, motivated by a neuronal spike trains study, we propose a novel point process regression…

Methodology · Statistics 2020-12-10 Xiwei Tang , Lexin Li

Missing data are often dealt with multiple imputation. A crucial part of the multiple imputation process is selecting sensible models to generate plausible values for incomplete data. A method based on posterior predictive checking is…

Computation · Statistics 2026-05-14 Mingyang Cai , Stef van Buuren , Gerko Vink

Heterogeneity is a hallmark of complex diseases. Regression-based heterogeneity analysis, which is directly concerned with outcome-feature relationships, has led to a deeper understanding of disease biology. Such an analysis identifies the…

Methodology · Statistics 2022-11-29 Ziye Luo , Xinyue Yao , Yifan Sun , Xinyan Fan

Building classification models that predict a binary class label on the basis of high dimensional multi-omics datasets poses several challenges, due to the typically widely differing characteristics of the data layers in terms of number of…

Methodology · Statistics 2020-08-04 Alessandra Cabassi , Denis Seyres , Mattia Frontini , Paul D. W. Kirk

Density regression characterizes the conditional density of the response variable given the covariates, and provides much more information than the commonly used conditional mean or quantile regression. However, it is often computationally…

Methodology · Statistics 2022-06-15 Yunlu Chen , Nan Zhang

We study the problem of identifying change points in high-dimensional generalized linear models, and propose an approach based on sample-weighted empirical risk minimization. Our method, Weighted ERM, encodes priors on the change points via…

Methodology · Statistics 2026-04-14 Gabriel Arpino , Ramji Venkataramanan