Related papers: Evaluating vaccine allocation strategies using sim…
We analyze an optimal control version of a simple SIR epidemiology model that includes a partially specified vaccination policy and takes into account fatigue from protracted application of social distancing measures. The model assumes…
Covid-19 has caused hundred of thousands of deaths and an economic damage amounting to trillions of dollars, creating a desire for the rapid development of vaccine. Once available, vaccine is gradually produced, evoking the question on how…
The waning of immunity after recovery or vaccination is a major factor accounting for the severity and prolonged duration of an array of epidemics, ranging from COVID-19 to diphtheria and pertussis. To study the effectiveness of different…
In this paper we analyze the impact of vaccinations on spread of the COVID-19 virus for different age groups. More specifically we examine the deployment of vaccines in the Nordic countries in a comparative analysis where we analyze factors…
Non-pharmacological interventions (NPIs), and in particular social distancing, in conjunction with the advent of effective vaccines at the end of 2020, aspired for the development of a protective immunity shield against the spread of…
In the context of SARS-CoV-2 pandemic, mathematical modelling has played a fundamental role for making forecasts, simulating scenarios and evaluating the impact of preventive political, social and pharmaceutical measures. Optimal control…
During various stages of the COVID-19 pandemic, countries implemented diverse vaccine management approaches, influenced by variations in infrastructure and socio-economic conditions. This article provides a comprehensive overview of…
Given the severe impact of COVID-19 on several societal levels, it is of crucial importance to model the impact of restriction measures on the pandemic evolution, so that governments are able to take informed decisions. Even though there…
We introduce a novel compartmental model accounting for the effects of vaccine efficacy, deployment rates and timing of initiation of deployment. We simulate different scenarios and initial conditions, and we find that higher abundancy and…
A year following the initial COVID-19 outbreak in China, many countries have approved emergency vaccines. Public-health practitioners and policymakers must understand the predicted populational willingness for vaccines and implement…
This study assesses the impact of COVID-19 vaccines through an epidemiological model that quantifies their role in pandemic control. We analyze an SIR-based model incorporating vaccination effects and calculate the basic reproduction…
Background: By the beginning of December 2020, some vaccines against COVID-19 already presented efficacy and security, which qualify them to be used in mass vaccination campaigns. Thus, setting up strategies of vaccination became crucial to…
This study explores the vaccine prioritization strategy to reduce the overall burden of the pandemic when the supply is limited. Existing methods conduct macro-level or simplified micro-level vaccine distribution by assuming the homogeneous…
Developing robust, quantitative methods to optimize resource allocations in response to epidemics has the potential to save lives and minimize health care costs. In this paper, we develop and apply a computationally efficient algorithm that…
The COVID-19 pandemic showed that stocking and procuring vaccines are different from the inventory holding problems of production. The safety of the supply is more important than cost minimization. The Hungarian inventory model is applied…
The COVID-19 pandemic has presented unprecedented challenges worldwide, with its impact varying significantly across different geographic and socioeconomic contexts. This study employs a clustering analysis to examine the diversity of…
We investigated the negative relationship between mortality and COVID-19 vaccination at ecological level, which has been established through clinical trials and other investigations at the individual level. We conducted an exploratory,…
Effective strategies of vaccine prioritization are essential to mitigate the impacts of severe infectious diseases. We investigate the role of infection fatality ratio (IFR) and social contact matrices on vaccination prioritization using a…
The Covid-19 outbreak of 2020 has required many governments to develop and adopt mathematical-statistical models of the pandemic for policy and planning purposes. To this end, this work provides a tutorial on building a compartmental model…
A major focus of debate about rationing guidelines for COVID-19 vaccines is whether and how to prioritize access for minority populations that have been particularly affected by the pandemic, and been the subject of historical and…