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Single-cell RNA sequencing (scRNA-seq) enables single-cell transcriptomic profiling, revealing cellular heterogeneity and rare populations. Recent deep learning models like Geneformer and Mouse-Geneformer perform well on tasks such as…

Genomics · Quantitative Biology 2025-07-11 Yuki Nishio , Takayoshi Yamashita , Keita Ito , Tsubasa Hirakawa , Hironobu Fujiyoshi

Iris restoration from complexly degraded iris images, aiming to improve iris recognition performance, is a challenging problem. Due to the complex degradation, directly training a convolutional neural network (CNN) without prior cannot…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Yubo Huang , Jia Wang , Peipei Li , Liuyu Xiang , Peigang Li , Zhaofeng He

While tokenized graph Transformers have demonstrated strong performance in node classification tasks, their reliance on a limited subset of nodes with high similarity scores for constructing token sequences overlooks valuable information…

Machine Learning · Computer Science 2025-02-18 Jinsong Chen , Hanpeng Liu , John E. Hopcroft , Kun He

Generative deep learning has become pivotal in molecular design for drug discovery, materials science, and chemical engineering. A widely used paradigm is to pretrain neural networks on string representations of molecules and fine-tune them…

Machine Learning · Computer Science 2025-03-21 Jonathan Pirnay , Jan G. Rittig , Alexander B. Wolf , Martin Grohe , Jakob Burger , Alexander Mitsos , Dominik G. Grimm

The adoption of Transformer-based models in natural language processing (NLP) has led to great success using a massive number of parameters. However, due to deployment constraints in edge devices, there has been a rising interest in the…

Computation and Language · Computer Science 2021-08-04 Klaudia Bałazy , Mohammadreza Banaei , Rémi Lebret , Jacek Tabor , Karl Aberer

Transform and entropy models are the two core components in deep image compression neural networks. Most existing learning-based image compression methods utilize convolutional-based transform, which lacks the ability to model long-range…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Atefeh Khoshkhahtinat , Ali Zafari , Piyush M. Mehta , Mohammad Akyash , Hossein Kashiani , Nasser M. Nasrabadi

Minimizing data storage poses a significant challenge in large-scale metagenomic projects. In this paper, we present a new method for improving the encoding of FASTQ files generated by metagenomic sequencing. This method incorporates…

Information Theory · Computer Science 2024-01-04 Diogo Pratas , Armando J. Pinho

Pre-trained Transformer-based models have achieved state-of-the-art performance for various Natural Language Processing (NLP) tasks. However, these models often have billions of parameters, and, thus, are too resource-hungry and…

Machine Learning · Computer Science 2021-09-29 Prakhar Ganesh , Yao Chen , Xin Lou , Mohammad Ali Khan , Yin Yang , Hassan Sajjad , Preslav Nakov , Deming Chen , Marianne Winslett

The discovery of new molecules based on the original chemical molecule distributions is of great importance in medicine. The graph transformer, with its advantages of high performance and scalability compared to traditional graph networks,…

Machine Learning · Computer Science 2025-04-30 Ji Shi , Chengxun Xie , Zhonghao Li , Xinming Zhang , Miao Zhang

This paper proposes a novel way of doing audio synthesis at the waveform level using Transformer architectures. We propose a deep neural network for generating waveforms, similar to wavenet. This is fully probabilistic, auto-regressive, and…

Sound · Computer Science 2021-07-09 Prateek Verma , Chris Chafe

We present ReFormer, a generative AI (GAI) model that can efficiently generate synthetic radio-frequency (RF) data, or RF fakes, statistically similar to the data it was trained on, or with modified statistics, in order to augment datasets…

Machine Learning · Computer Science 2025-01-03 Yagna Kaasaragadda , Silvija Kokalj-Filipovic

Transfer learning has emerged as a powerful technique in many application problems, such as computer vision and natural language processing. However, this technique is largely ignored in application to genetic data analysis. In this paper,…

Applications · Statistics 2022-06-22 Jinghang Lin , Shan Zhang , Qing Lu

Genomic selection (GS), as a critical crop breeding strategy, plays a key role in enhancing food production and addressing the global hunger crisis. The predominant approaches in GS currently revolve around employing statistical methods for…

Machine Learning · Computer Science 2024-06-25 Renqi Chen , Wenwei Han , Haohao Zhang , Haoyang Su , Zhefan Wang , Xiaolei Liu , Hao Jiang , Wanli Ouyang , Nanqing Dong

The recent super-exponential growth in the amount of sequencing data generated worldwide has put techniques for compressed storage into the focus. Most available solutions, however, are strictly tied to specific bioinformatics formats,…

Genomics · Quantitative Biology 2021-11-01 Łukasz Roguski , Paolo Ribeca

Motivation The Burrows-Wheeler transform (BWT) is the foundation of many algorithms for compression and indexing of text data, but the cost of computing the BWT of very large string collections has prevented these techniques from being…

Data Structures and Algorithms · Computer Science 2015-03-20 Anthony J. Cox , Markus J. Bauer , Tobias Jakobi , Giovanna Rosone

Gene-gene interactions play a crucial role in the manifestation of complex human diseases. Uncovering significant gene-gene interactions is a challenging task. Here, we present an innovative approach utilizing data-driven computational…

Artificial Intelligence · Computer Science 2024-10-22 Yifan Wu , Yuntao Yang , Zirui Liu , Zhao Li , Khushbu Pahwa , Rongbin Li , Wenjin Zheng , Xia Hu , Zhaozhuo Xu

DNA is a leading candidate as the next archival storage media due to its density, durability and sustainability. To read (and write) data DNA storage exploits technology that has been developed over decades to sequence naturally occurring…

Emerging Technologies · Computer Science 2022-05-12 Jasmine Quah , Omer Sella , Thomas Heinis

Transformer-based models have emerged as promising tools for time series forecasting. However, these model cannot make accurate prediction for long input time series. On the one hand, they failed to capture global dependencies within time…

Machine Learning · Computer Science 2023-08-16 YanJun Zhao , Ziqing Ma , Tian Zhou , Liang Sun , Mengni Ye , Yi Qian

Transformers have reached remarkable success in sequence modeling. However, these models have efficiency issues as they need to store all the history token-level representations as memory. We present Memformer, an efficient neural network…

Computation and Language · Computer Science 2022-04-14 Qingyang Wu , Zhenzhong Lan , Kun Qian , Jing Gu , Alborz Geramifard , Zhou Yu

Removing modeling constraints and unifying architectures across domains has been a key driver of the recent progress in training large multimodal models. However, most of these models still rely on many separately trained components such as…

Machine Learning · Computer Science 2025-05-20 Michael Tschannen , André Susano Pinto , Alexander Kolesnikov