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We live in a period where bio-informatics is rapidly expanding, a significant quantity of genomic data has been produced as a result of the advancement of high-throughput genome sequencing technology, raising concerns about the costs…

Quantitative Methods · Quantitative Biology 2023-03-10 Mehedi Hasan Sarkar , Adnan Ferdous Ashrafi

This work introduces a Transformer-based image compression system. It has the flexibility to switch between the standard image reconstruction and the denoising reconstruction from a single compressed bitstream. Instead of training separate…

Image and Video Processing · Electrical Eng. & Systems 2024-02-21 Yi-Hsin Chen , Kuan-Wei Ho , Shiau-Rung Tsai , Guan-Hsun Lin , Alessandro Gnutti , Wen-Hsiao Peng , Riccardo Leonardi

Over the past years, the ever-growing trend on data storage demand, more specifically for "cold" data (rarely accessed data), has motivated research for alternative systems of data storage. Because of its biochemical characteristics,…

Machine Learning · Computer Science 2022-03-21 Xavier Pic , Marc Antonini

We present a Compression Tool, "GenBit Compress", for genetic sequences based on our new proposed "GenBit Compress Algorithm". Our Tool achieves the best compression ratios for Entire Genome (DNA sequences) . Significantly better…

Mathematical Software · Computer Science 2010-07-15 P. Raja Rajeswari , Allam Apparo , V. K. Kumar

One critical component in lossy deep image compression is the entropy model, which predicts the probability distribution of the quantized latent representation in the encoding and decoding modules. Previous works build entropy models upon…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Yichen Qian , Ming Lin , Xiuyu Sun , Zhiyu Tan , Rong Jin

DNA sequencing technology has advanced to a point where storage is becoming the central bottleneck in the acquisition and mining of more data. Large amounts of data are vital for genomics research, and generic compression tools, while…

Information Theory · Computer Science 2016-11-15 Bobbie Chern , Idoia Ochoa , Alexandros Manolakos , Albert No , Kartik Venkat , Tsachy Weissman

Generative models have demonstrated strong performance in conditional settings and can be viewed as a form of data compression, where the condition serves as a compact representation. However, their limited controllability and…

Machine Learning · Computer Science 2025-07-04 Xiao Li , Liangji Zhu , Anand Rangarajan , Sanjay Ranka

We propose a new compression scheme for genomic data given as sequence fragments called reads. The scheme uses a reference genome at the decoder side only, freeing the encoder from the burdens of storing references and performing…

Information Theory · Computer Science 2023-02-10 Yotam Gershon , Yuval Cassuto

DNA has emerged as a promising alternative for long-term data storage due to its high capacity, durability, and low-energy potential. However, storing data in DNA presents several challenges. First, it requires complex and costly…

Other Quantitative Biology · Quantitative Biology 2025-11-20 Sara Al Sayyed , Aline Roumy , Thomas Maugey

Stochastic generators are essential to produce synthetic realizations that preserve target statistical properties. We propose GenFormer, a stochastic generator for spatio-temporal multivariate stochastic processes. It is constructed using a…

Machine Learning · Computer Science 2024-02-06 Haoran Zhao , Wayne Isaac Tan Uy

Transformer-based models have achieved remarkable success in natural language and vision tasks, but their application to gene expression analysis remains limited due to data sparsity, high dimensionality, and missing values. We present…

Machine Learning · Computer Science 2025-04-15 Shuai Jiang , Saeed Hassanpour

Sequential data is being generated at an unprecedented pace in various forms, including text and genomic data. This creates the need for efficient compression mechanisms to enable better storage, transmission and processing of such data. To…

Computation and Language · Computer Science 2018-11-21 Mohit Goyal , Kedar Tatwawadi , Shubham Chandak , Idoia Ochoa

Compressed file formats are the corner stone of efficient data storage and transmission, yet their potential for representation learning remains largely underexplored. We introduce TEMPEST (TransformErs froM comPressed rEpreSenTations), a…

Technology progress in DNA sequencing boosts the genomic database growth at faster and faster rate. Compression, accompanied with random access capabilities, is the key to maintain those huge amounts of data. In this paper we present an…

Computational Engineering, Finance, and Science · Computer Science 2011-03-14 Szymon Grabowski , Sebastian Deorowicz

Data compression plays an important role to deal with high volumes of DNA sequences in the field of Bioinformatics. Again data compression techniques directly affect the alignment of DNA sequences. So the time needed to decompress a…

Computational Engineering, Finance, and Science · Computer Science 2012-11-13 Subhankar Roy , Sunirmal Khatua , Sudipta Roy , Samir K. Bandyopadhyay

Text compression shrinks textual data while keeping crucial information, eradicating constraints on storage, bandwidth, and computational efficacy. The integration of lossless compression techniques with transformer-based text decompression…

Computation and Language · Computer Science 2024-12-23 Chowdhury Mofizur Rahman , Mahbub E Sobhani , Anika Tasnim Rodela , Swakkhar Shatabda

Over the past years, the ever-growing trend on data storage demand, more specifically for "cold" data (rarely accessed data), has motivated research for alternative systems of data storage. Because of its biochemical characteristics,…

Image and Video Processing · Electrical Eng. & Systems 2023-06-23 Xavier Pic , Eva Gil San Antonio , Melpomeni Dimopoulou , Marc Antonini

Recently, learned image compression methods have outperformed traditional hand-crafted ones including BPG. One of the keys to this success is learned entropy models that estimate the probability distribution of the quantized latent…

Image and Video Processing · Electrical Eng. & Systems 2022-07-22 Jun-Hyuk Kim , Byeongho Heo , Jong-Seok Lee

Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…

Genomics · Quantitative Biology 2025-05-07 Frederikke I. Marin , Dennis Pultz , Wouter Boomsma

Genome modeling conventionally treats gene sequence as a language, reflecting its structured motifs and long-range dependencies analogous to linguistic units and organization principles such as words and syntax. Recent studies utilize…

Machine Learning · Computer Science 2025-05-06 Lei Mao , Yuanhe Tian , Yan Song
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