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Machine learning techniques have found their way into computational chemistry as indispensable tools to accelerate atomistic simulations and materials design. In addition, machine learning approaches hold the potential to boost the…

Chemical Physics · Physics 2025-10-03 Johannes Voss

Machine learning algorithms frequently require careful tuning of model hyperparameters, regularization terms, and optimization parameters. Unfortunately, this tuning is often a "black art" that requires expert experience, unwritten rules of…

Machine Learning · Statistics 2012-08-30 Jasper Snoek , Hugo Larochelle , Ryan P. Adams

Machine learning classification tasks often benefit from predicting a set of possible labels with confidence scores to capture uncertainty. However, existing methods struggle with the high-dimensional nature of the data and the lack of…

Machine Learning · Computer Science 2024-07-08 Rui Luo , Zhixin Zhou

One of the core applications of machine learning to knowledge discovery consists on building a function (a hypothesis) from a given amount of data (for instance a decision tree or a neural network) such that we can use it afterwards to…

Machine Learning · Computer Science 2007-05-23 Carlos Domingo , Ricard Gavalda , Osamu Watanabe

Deep learning methods are widely applied in digital pathology to address clinical challenges such as prognosis and diagnosis. As one of the most recent applications, deep models have also been used to extract molecular features from whole…

Image and Video Processing · Electrical Eng. & Systems 2022-03-29 Amir Safarpoor , Jason D. Hipp , H. R. Tizhoosh

Machine learning is the dominant approach to artificial intelligence, through which computers learn from data and experience. In the framework of supervised learning, a necessity for a computer to learn from data accurately and efficiently…

Machine Learning · Statistics 2023-01-25 Amir R. Asadi

This work deviates from easy-to-define class boundaries for object interactions. For the task of object interaction recognition, often captured using an egocentric view, we show that semantic ambiguities in verbs and recognising…

Computer Vision and Pattern Recognition · Computer Science 2017-04-24 Michael Wray , Davide Moltisanti , Walterio Mayol-Cuevas , Dima Damen

Reliable probability estimation is of crucial importance in many real-world applications where there is inherent (aleatoric) uncertainty. Probability-estimation models are trained on observed outcomes (e.g. whether it has rained or not, or…

The literature on "benign overfitting" in overparameterized models has been mostly restricted to regression or binary classification; however, modern machine learning operates in the multiclass setting. Motivated by this discrepancy, we…

Machine Learning · Statistics 2023-07-13 Ke Wang , Vidya Muthukumar , Christos Thrampoulidis

Machine learning potentials have revolutionised the field of atomistic simulations in recent years and are becoming a mainstay in the toolbox of computational scientists. This paper aims to provide an overview and introduction into machine…

Chemical Physics · Physics 2024-10-02 Fabian L. Thiemann , Niamh O'Neill , Venkat Kapil , Angelos Michaelides , Christoph Schran

Data preparation, i.e. the process of transforming raw data into a format that can be used for training effective machine learning models, is a tedious and time-consuming task. For image data, preprocessing typically involves a sequence of…

Computer Vision and Pattern Recognition · Computer Science 2021-04-30 Tran Ngoc Minh , Mathieu Sinn , Hoang Thanh Lam , Martin Wistuba

Neural networks have proven successful at learning from complex data distributions by acting as universal function approximators. However, they are often overconfident in their predictions, which leads to inaccurate and miscalibrated…

Machine Learning · Computer Science 2021-02-23 Jeffrey Willette , Juho Lee , Sung Ju Hwang

We consider multi-class classification where the predictor has a hierarchical structure that allows for a very large number of labels both at train and test time. The predictive power of such models can heavily depend on the structure of…

Machine Learning · Statistics 2017-03-06 Yacine Jernite , Anna Choromanska , David Sontag

Fairness-aware machine learning has recently attracted various communities to mitigate discrimination against certain societal groups in data-driven tasks. For fair supervised learning, particularly in pre-processing, there have been two…

Machine Learning · Computer Science 2026-01-21 Jinwon Sohn , Guang Lin , Qifan Song

Human perception of the empirical world involves recognizing the diverse appearances, or 'modalities', of underlying objects. Despite the longstanding consideration of this perspective in philosophy and cognitive science, the study of…

Machine Learning · Computer Science 2023-12-19 Zhou Lu

Prospection is an important part of how humans come up with new task plans, but has not been explored in depth in robotics. Predicting multiple task-level is a challenging problem that involves capturing both task semantics and continuous…

Machine Learning · Computer Science 2017-11-13 Chris Paxton , Kapil Katyal , Christian Rupprecht , Raman Arora , Gregory D. Hager

We consider training probabilistic classifiers in the case of a large number of classes. The number of classes is assumed too large to perform exact normalisation over all classes. To account for this we consider a simple approach that…

Machine Learning · Statistics 2016-07-08 David Barber , Aleksandar Botev

We investigate the application of hierarchical classification schemes to the annotation of gene function based on several characteristics of protein sequences including phylogenic descriptors, sequence based attributes, and predicted…

Genomics · Quantitative Biology 2007-05-23 Babak Shahbaba , Radford M. Neal

Predicting the structure of multi-protein complexes is a grand challenge in biochemistry, with major implications for basic science and drug discovery. Computational structure prediction methods generally leverage pre-defined structural…

Biomolecules · Quantitative Biology 2021-01-26 Stephan Eismann , Raphael J. L. Townshend , Nathaniel Thomas , Milind Jagota , Bowen Jing , Ron O. Dror

Monte Carlo methods are essential across diverse scientific fields, yet their efficiency is frequently hampered by critical slowing down-a sharp increase in autocorrelation times near phase transitions. Although deep learning approaches,…

Machine Learning · Computer Science 2026-05-18 Piotr Białas , Piotr Korcyl , Tomasz Stebel , Dawid Zapolski