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Slater determinants have underpinned quantum chemistry for nearly a century, yet their full potential has remained challenging to exploit. In this work, we show that a variational wavefunction composed of a few hundred optimized…

Chemical Physics · Physics 2026-04-17 Clemens Giuliani , Jannes Nys , Rocco Martinazzo , Giuseppe Carleo , Riccardo Rossi

We investigate the properties of the molecular quantum dot (Holstein-Anderson) model using numerical and analytical techniques. Path integral Monte Carlo simulations for the cumulants of the distribution function of the phonon coordinate…

Strongly Correlated Electrons · Physics 2015-04-23 Juliane Klatt , Lothar Mühlbacher , Andreas Komnik

The development of tailored materials for specific applications is an active field of research in chemistry, material science and drug discovery. The number of possible molecules that can be obtained from a set of atomic species grow…

Determining the properties of molecules and materials is one of the premier applications of quantum computing. A major question in the field is how to use imperfect near-term quantum computers to solve problems of practical value. Inspired…

Combinatorial optimization problems are typically formulated using Quadratic Unconstrained Binary Optimization (QUBO), where constraints are enforced through penalty terms that introduce auxiliary variables and rapidly increase Hamiltonian…

Quantum Physics · Physics 2026-02-10 Shashank Sanjay Bhat , Peiyong Wang , Joseph West , Udaya Parampalli

Grover's database search algorithm is the optimal algorithm for finding a desired object from an unsorted collection of items. Although it was discovered in the context of quantum computation, it is simple and versatile enough to be…

General Physics · Physics 2007-12-03 Aavishkar A. Patel

In this work we demonstrate a practical prospect of using quantum annealers for simulation of molecular dynamics. A methodology developed for this goal, dubbed Quantum Differential Equations (QDE), is applied to propagate classical…

Optimally-shaped electromagnetic fields have the capacity to coherently control the dynamics of quantum systems and thus offer a promising means for controlling molecular transformations relevant to chemical, biological, and materials…

Quantum Physics · Physics 2021-06-08 Alicia B. Magann , Matthew D. Grace , Herschel A. Rabitz , Mohan Sarovar

We study the impact of the potential parameters of the q-deformed modified P\"oschl-Teller potential on the thermodynamic performance of a quantum Otto cycle, where the $q$-deformed modified P\"oschl-Teller potential serves as the working…

Quantum Physics · Physics 2026-05-26 Collins O. Edet , Norshamsuri Ali , Rosdisham Endut , O. Abah

Quantum Optimal Control Theory (QOCT) provides the necessary tools to theoretically design driving fields capable of controlling a quantum system towards a given state or along a prescribed path in Hilbert space. This theory must be…

Atomic and Molecular Clusters · Physics 2013-05-30 Alberto Castro , Jan Werschnik , Eberhard K. U. Gross

Quantum computing holds transformative potential for optimizing large-scale drone fleet operations, yet its near-term limitations necessitate hybrid approaches blending classical and quantum techniques. This work introduces Quantum Unmanned…

Emerging Technologies · Computer Science 2025-04-01 James B. Holliday , Darren Blount , Hoang Quan Nguyen , Samee U. Khan , Khoa Luu

The notion of the optimized perturbation, which has been successfully applied to energy eigenvalues, is generalized to treat wave functions of quantum systems. The key ingredient is to construct an envelope of a set of perturbative wave…

High Energy Physics - Theory · Physics 2014-11-18 T. Hatsuda , T. Kunihiro , T. Tanaka

This tutorial offers a quick, hands-on introduction to solving Quadratic Unconstrained Binary Optimization (QUBO) models on currently available quantum computers and their simulators. We cover both IBM and D-Wave machines: IBM utilizes a…

Quantum Physics · Physics 2025-06-18 Arul Mazumder , Sridhar Tayur

We study the problem of estimating frequency response functions of systems of coupled, classical harmonic oscillators using a quantum computer. The functional form of these response functions can be mapped to a corresponding eigenproblem of…

Quantum Physics · Physics 2025-11-14 Sven Danz , Mario Berta , Stefan Schröder , Pascal Kienast , Frank K. Wilhelm , Alessandro Ciani

The reconstruction of trajectories of charged particles is a key computational challenge for current and future collider experiments. Considering the rapid progress in quantum computing, it is crucial to explore its potential for this and…

The quantum properties of electromagnetic, mechanical or other harmonic oscillators can be revealed by investigating their strong coherent coupling to a single quantum two level system in an approach known as cavity quantum electrodynamics…

A new concept of the molecular structure optimization method based on quantum dynamics computations is presented. Nuclei are treated as quantum mechanical particles, as are electrons, and the many-body wave function of the system is…

Despite their simplicity, quantum harmonic oscillators are ubiquitous in the modeling of physical systems. They are able to capture universal properties that serve as reference for the more complex systems found in nature. In this spirit,…

Quantum Physics · Physics 2025-03-04 Benedikt M. Reible , Ana Djurdjevac , Luigi Delle Site

Quantum Annealing (QA) can efficiently solve combinatorial optimization problems whose objective functions are represented by Quadratic Unconstrained Binary Optimization (QUBO) formulations. For broader applicability of QA, quadratization…

Quantum Physics · Physics 2025-07-29 Hyakka Nakada , Shu Tanaka

In this work, we introduce a novel Quadratic Binary Optimization (QBO) framework for training a quantized neural network. The framework enables the use of arbitrary activation and loss functions through spline interpolation, while Forward…

Machine Learning · Computer Science 2025-12-09 Wenxin Li , Chuan Wang , Hongdong Zhu , Qi Gao , Yin Ma , Hai Wei , Kai Wen