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Ocular disease affects billions of individuals unevenly worldwide. It continues to increase in prevalence with trends of growing populations of diabetic people, increasing life expectancies, decreasing ophthalmologist availability, and…

Computers and Society · Computer Science 2025-07-29 Shiv Garg , Ginny Berkemeier

This paper reports a case study on how explainability requirements were elicited during the development of an AI system for predicting cerebral palsy (CP) risk in infants. Over 18 months, we followed a development team and hospital…

Software Engineering · Computer Science 2026-01-06 Tor Sporsem , Stine Rasdal Finserås , Lars Adde , Inga Strümke

Current models on Explainable Artificial Intelligence (XAI) have shown an evident and quantified lack of reliability for measuring feature-relevance when statistically entangled features are proposed for training deep classifiers. There has…

Signal Processing · Electrical Eng. & Systems 2023-02-27 Juan Manuel Mayor-Torres , Sara Medina-DeVilliers , Tessa Clarkson , Matthew D. Lerner , Giuseppe Riccardi

Interpretability is a key factor in the design of automatic classifiers for medical diagnosis. Deep learning models have been proven to be a very effective classification algorithm when trained in a supervised way with enough data. The main…

Machine Learning · Statistics 2018-09-25 Jordi de la Torre , Aida Valls , Domenec Puig , Pere Romero-Aroca

Dermatological conditions affect 1.9 billion people globally, yet accurate diagnosis remains challenging due to limited specialist availability and complex clinical presentations. Family history significantly influences skin disease…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Satya Narayana Panda , Vaishnavi Kukkala , Spandana Iyer

Diabetic retinopathy is a severe complication of diabetes that can lead to permanent blindness if not treated promptly. Early and accurate diagnosis of the disease is essential for successful treatment. This paper introduces a deep learning…

Image and Video Processing · Electrical Eng. & Systems 2024-03-14 Hossein Shakibania , Sina Raoufi , Behnam Pourafkham , Hassan Khotanlou , Muharram Mansoorizadeh

Generative artificial intelligence (AI) is rapidly transforming medical imaging by enabling capabilities such as data synthesis, image enhancement, modality translation, and spatiotemporal modeling. This review presents a comprehensive and…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Xuanru Zhou , Cheng Li , Shuqiang Wang , Ye Li , Tao Tan , Hairong Zheng , Shanshan Wang

Diabetic retinopathy (DR) is the most common form of diabetic eye disease. Retinopathy can affect all diabetic patients and becomes particularly dangerous, increasing the risk of blindness, if it is left untreated. The success rate of its…

Computer Vision and Pattern Recognition · Computer Science 2019-02-11 Oindrila Saha , Rachana Sathish , Debdoot Sheet

The discussions around Artificial Intelligence (AI) and medical imaging are centered around the success of deep learning algorithms. As new algorithms enter the market, it is important for practicing radiologists to understand the pitfalls…

Image and Video Processing · Electrical Eng. & Systems 2022-11-28 Rishi Gadepally , Andrew Gomella , Eric Gingold , Paras Lakhani

The last decades have seen significant advancements in non-invasive neuroimaging technologies that have been increasingly adopted to examine human brain development. However, these improvements have not necessarily been followed by more…

Neurons and Cognition · Quantitative Biology 2021-12-28 Mehrin Kiani , Javier Andreu-Perez , Hani Hagras , Silvia Rigato , Maria Laura Filippetti

Typical state of the art flow cytometry data samples consists of measures of more than 100.000 cells in 10 or more features. AI systems are able to diagnose such data with almost the same accuracy as human experts. However, there is one…

The accuracy of coronary artery disease (CAD) diagnosis is dependent on a variety of factors, including demographic, symptom, and medical examination, ECG, and echocardiography data, among others. In this context, artificial intelligence…

Artificial Intelligence · Computer Science 2023-08-30 Elham Nasarian , Danial Sharifrazi , Saman Mohsenirad , Kwok Tsui , Roohallah Alizadehsani

Accurate diagnosis and prognosis of Alzheimer's disease are crucial to develop new therapies and reduce the associated costs. Recently, with the advances of convolutional neural networks, methods have been proposed to automate these two…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

Accurate staging of Diabetic Retinopathy (DR) is essential for guiding timely interventions and preventing vision loss. However, current staging models are hardly interpretable, and most public datasets contain no clinical reasoning or…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Chenjun Li , Laurin Lux , Alexander H. Berger , Martin J. Menten , Mert R. Sabuncu , Johannes C. Paetzold

Deep neural networks (DNN) have achieved unprecedented performance in computer-vision tasks almost ubiquitously in business, technology, and science. While substantial efforts are made to engineer highly accurate architectures and provide…

Image and Video Processing · Electrical Eng. & Systems 2022-09-08 Sumedha Singla

Diabetic retinopathy (DR) is one of the leading causes of blindness. However, no specific symptoms of early DR lead to a delayed diagnosis, which results in disease progression in patients. To determine the disease severity levels,…

Computer Vision and Pattern Recognition · Computer Science 2020-11-05 Li Tian , Liyan Ma , Zhijie Wen , Shaorong Xie , Yupeng Xu

Recent studies suggest that early stages of diabetic retinopathy (DR) can be diagnosed by monitoring vascular changes in the deep vascular complex. In this work, we investigate a novel method for automated DR grading based on optical…

Image and Video Processing · Electrical Eng. & Systems 2022-12-22 Linus Kreitner , Ivan Ezhov , Daniel Rueckert , Johannes C. Paetzold , Martin J. Menten

Diabetes is a globally prevalent disease that can cause visible microvascular complications such as diabetic retinopathy and macular edema in the human eye retina, the images of which are today used for manual disease screening. This…

Image and Video Processing · Electrical Eng. & Systems 2019-04-19 Jaakko Sahlsten , Joel Jaskari , Jyri Kivinen , Lauri Turunen , Esa Jaanio , Kustaa Hietala , Kimmo Kaski

Retinal imaging serves as a valuable tool for diagnosis of various diseases. However, reading retinal images is a difficult and time-consuming task even for experienced specialists. The fundamental step towards automated retinal image…

Computer Vision and Pattern Recognition · Computer Science 2020-05-28 Liangzhi Li , Manisha Verma , Yuta Nakashima , Ryo Kawasaki , Hajime Nagahara

Medical image classification is crucial for diagnosis and treatment, benefiting significantly from advancements in artificial intelligence. The paper reviews recent progress in the field, focusing on three levels of solutions: basic,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-06 Loan Dao , Ngoc Quoc Ly