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Retinopathy of prematurity (ROP) is a severe condition affecting premature infants, leading to abnormal retinal blood vessel growth, retinal detachment, and potential blindness. While semi-automated systems have been used in the past to…

Explainable artificial intelligence (XAI) has become increasingly important in biomedical image analysis to promote transparency, trust, and clinical adoption of DL models. While several surveys have reviewed XAI techniques, they often lack…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Getamesay Haile Dagnaw , Yanming Zhu , Muhammad Hassan Maqsood , Wencheng Yang , Xingshuai Dong , Xuefei Yin , Alan Wee-Chung Liew

Artificial intelligence (AI) systems utilizing deep neural networks (DNNs) and machine learning (ML) algorithms are widely used for solving important problems in bioinformatics, biomedical informatics, and precision medicine. However,…

Quantitative Methods · Quantitative Biology 2023-02-24 Md. Rezaul Karim , Tanhim Islam , Oya Beyan , Christoph Lange , Michael Cochez , Dietrich Rebholz-Schuhmann , Stefan Decker

When we deploy machine learning models in high-stakes medical settings, we must ensure these models make accurate predictions that are consistent with known medical science. Inherently interpretable networks address this need by explaining…

Computer Vision and Pattern Recognition · Computer Science 2021-10-06 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

Age-related macular degeneration (AMD) is the most common cause of blindness in developed countries, especially in people over 60 years of age. The workload of specialists and the healthcare system in this field has increased in recent…

Image and Video Processing · Electrical Eng. & Systems 2022-02-07 Saman Sotoudeh-Paima , Ata Jodeiri , Fedra Hajizadeh , Hamid Soltanian-Zadeh

The diabetic retinopathy is timely diagonalized through color eye fundus images by experienced ophthalmologists, in order to recognize potential retinal features and identify early-blindness cases. In this paper, it is proposed to extract…

Computer Vision and Pattern Recognition · Computer Science 2017-07-31 Ibrahim Sadek , Mohamed Elawady , Abd El Rahman Shabayek

As the manufacturing industry advances with sensor integration and automation, the opaque nature of deep learning models in machine learning poses a significant challenge for fault detection and diagnosis. And despite the related predictive…

Artificial Intelligence · Computer Science 2024-06-11 Ahmed Maged , Salah Haridy , Herman Shen

Objective. This paper presents an overview of generalizable and explainable artificial intelligence (XAI) in deep learning (DL) for medical imaging, aimed at addressing the urgent need for transparency and explainability in clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Ahmad Chaddad , Yan Hu , Yihang Wu , Binbin Wen , Reem Kateb

Diagnosing different retinal diseases from Spectral Domain Optical Coherence Tomography (SD-OCT) images is a challenging task. Different automated approaches such as image processing, machine learning and deep learning algorithms have been…

Image and Video Processing · Electrical Eng. & Systems 2020-05-19 Sharif Amit Kamran , Sourajit Saha , Ali Shihab Sabbir , Alireza Tavakkoli

The transformative power of Convolutional Neural Networks (CNNs) in radiology diagnostics is examined in this study, with a focus on interpretability, effectiveness, and ethical issues. With an altered DenseNet architecture, the CNN…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Keshav Kumar K. , Dr N V S L Narasimham

Methods for automated retinal vessel segmentation play an important role in the treatment and diagnosis of many eye and systemic diseases. With the fast development of deep learning methods, more and more retinal vessel segmentation methods…

Image and Video Processing · Electrical Eng. & Systems 2023-06-13 Gorana Gojić , Ognjen Kundačina , Dragiša Mišković , Dinu Dragan

Teleophthalmology holds a great potential to improve the quality, access, and affordability in health care. For patients, it can reduce the need for travel and provide the access to a superspecialist. Ophthalmology lends itself easily to…

Computer Vision and Pattern Recognition · Computer Science 2010-02-12 D. Jayanthi , N. Devi , S. SwarnaParvathi

With an increase in deep learning-based methods, the call for explainability of such methods grows, especially in high-stakes decision making areas such as medical image analysis. This survey presents an overview of eXplainable Artificial…

Image and Video Processing · Electrical Eng. & Systems 2022-05-06 Bas H. M. van der Velden , Hugo J. Kuijf , Kenneth G. A. Gilhuijs , Max A. Viergever

The growing adoption of artificial intelligence in healthcare has raised concerns about the transparency and trustworthiness of AI-driven medical diagnosis systems. Many existing models operate as black boxes, limiting clinicians' ability…

Human-Computer Interaction · Computer Science 2026-04-21 Altynbek Seitenov , Ainur Nurzhanova , Azhar Bekbussinova , Yerassyl Bolatkan

Black-box deep learning approaches have showcased significant potential in the realm of medical image analysis. However, the stringent trustworthiness requirements intrinsic to the medical field have catalyzed research into the utilization…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Yequan Bie , Luyang Luo , Hao Chen

Diabetic retinopathy (DR) results in vision loss if not treated early. A computer-aided diagnosis (CAD) system based on retinal fundus images is an efficient and effective method for early DR diagnosis and assisting experts. A…

Computer Vision and Pattern Recognition · Computer Science 2019-08-23 Norah Asiri , Muhammad Hussain , Fadwa Al Adel , Nazih Alzaidi

In recent years, the field of medicine has been increasingly adopting artificial intelligence (AI) technologies to provide faster and more accurate disease detection, prediction, and assessment. In this study, we propose an interpretable AI…

Rare diseases represent the long tail of medical imaging, where AI models often fail due to the scarcity of representative training data. In clinical workflows, radiologists frequently consult case reports and literature when confronted…

Computation and Language · Computer Science 2025-11-10 Ha Young Kim , Jun Li , Ana Beatriz Solana , Carolin M. Pirkl , Benedikt Wiestler , Julia A. Schnabel , Cosmin I. Bercea

Much effort is being made by the researchers in order to detect and diagnose diabetic retinopathy (DR) accurately automatically. The disease is very dangerous as it can cause blindness suddenly if it is not continuously screened. Therefore,…

Image and Video Processing · Electrical Eng. & Systems 2020-12-24 Eman AbdelMaksoud , Sherif Barakat , Mohammed Elmogy

Widespread outreach programs using remote retinal imaging have proven to decrease the risk from diabetic retinopathy, the leading cause of blindness in the US. However, this process still requires manual verification of image quality and…

Computer Vision and Pattern Recognition · Computer Science 2016-12-14 Arjun Raj Rajanna , Kamelia Aryafar , Rajeev Ramchandran , Christye Sisson , Ali Shokoufandeh , Raymond Ptucha
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