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Though deep learning has shown successful performance in classifying the label and severity stage of certain diseases, most of them give few explanations on how to make predictions. Inspired by Koch's Postulates, the foundation in…

Image and Video Processing · Electrical Eng. & Systems 2022-05-02 Yuhao Niu , Lin Gu , Yitian Zhao , Feng Lu

Interpretability is crucial to enhance trust in machine learning models for medical diagnostics. However, most state-of-the-art image classifiers based on neural networks are not interpretable. As a result, clinicians often resort to known…

Deep neural network models have been proven to be very successful in image classification tasks, also for medical diagnosis, but their main concern is its lack of interpretability. They use to work as intuition machines with high…

Machine Learning · Computer Science 2019-04-26 Jordi de la Torre , Aida Valls , Domenec Puig

We proposed a deep learning method for interpretable diabetic retinopathy (DR) detection. The visual-interpretable feature of the proposed method is achieved by adding the regression activation map (RAM) after the global averaging pooling…

Computer Vision and Pattern Recognition · Computer Science 2019-12-04 Zhiguang Wang , Jianbo Yang

In this paper, we propose an explainable and interpretable diabetic retinopathy (ExplainDR) classification model based on neural-symbolic learning. To gain explainability, a highlevel symbolic representation should be considered in decision…

Machine Learning · Computer Science 2022-04-05 Se-In Jang , Michael J. A. Girard , Alexandre H. Thiery

The significant portion of diabetic patients was affected due to major blindness caused by Diabetic retinopathy (DR). For diabetic retinopathy, lesion segmentation, and detection the comprehensive examination is delved into the deep…

Artificial Intelligence · Computer Science 2024-11-20 Syed Mohd Faisal Malik , Md Tabrez Nafis , Mohd Abdul Ahad , Safdar Tanweer

In recent years, deep learning (DL) techniques have provided state-of-the-art performance on different medical imaging tasks. However, the availability of good quality annotated medical data is very challenging due to involved time…

Machine Learning · Computer Science 2020-12-29 Muhammad Ahtazaz Ahsan , Adnan Qayyum , Junaid Qadir , Adeel Razi

Retinal imaging provides a non-invasive window into systemic microvascular health and has emerged as a potential biomarker for systemic diseases. However, whether retinal features encode biologically meaningful systemic signals that can be…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Mini Han Wang , Liting Huang , Wei Hong , Boonthawan Wingwon

Machine learning methods have shown large potential for the automatic early diagnosis of Alzheimer's Disease (AD). However, some machine learning methods based on imaging data have poor interpretability because it is usually unclear how…

Though deep learning has shown successful performance in classifying the label and severity stage of certain disease, most of them give few evidence on how to make prediction. Here, we propose to exploit the interpretability of deep…

Computer Vision and Pattern Recognition · Computer Science 2020-03-16 Yuhao Niu , Lin Gu , Feng Lu , Feifan Lv , Zongji Wang , Imari Sato , Zijian Zhang , Yangyan Xiao , Xunzhang Dai , Tingting Cheng

Automatic classification of diabetic retinopathy from retinal images has been widely studied using deep neural networks with impressive results. However, there is a clinical need for estimation of the uncertainty in the classifications, a…

Computer Vision and Pattern Recognition · Computer Science 2022-02-03 Joel Jaskari , Jaakko Sahlsten , Theodoros Damoulas , Jeremias Knoblauch , Simo Särkkä , Leo Kärkkäinen , Kustaa Hietala , Kimmo Kaski

The diabetic retinopathy is timely diagonalized through color eye fundus images by experienced ophthalmologists, in order to recognize potential retinal features and identify early-blindness cases. In this paper, it is proposed to extract…

Computer Vision and Pattern Recognition · Computer Science 2017-07-31 Ibrahim Sadek , Mohamed Elawady , Abd El Rahman Shabayek

Deep learning based approaches to Computer Aided Diagnosis (CAD) typically pose the problem as an image classification (Normal or Abnormal) problem. These systems achieve high to very high accuracy in specific disease detection for which…

Computer Vision and Pattern Recognition · Computer Science 2020-10-06 Aniket Joshi , Gaurav Mishra , Jayanthi Sivaswamy

Objective: Radiomics-driven Computer Aided Diagnosis (CAD) has shown considerable promise in recent years as a potential tool for improving clinical decision support in medical oncology, particularly those based around the concept of…

Artificial Intelligence · Computer Science 2017-10-31 Devinder Kumar , Graham W. Taylor , Alexander Wong

Diabetic retinopathy (DR) is one of the leading causes of blindness. However, no specific symptoms of early DR lead to a delayed diagnosis, which results in disease progression in patients. To determine the disease severity levels,…

Computer Vision and Pattern Recognition · Computer Science 2020-11-05 Li Tian , Liyan Ma , Zhijie Wen , Shaorong Xie , Yupeng Xu

Diabetic retinopathy is a common complication of diabetes, and monitoring the progression of retinal abnormalities using fundus imaging is crucial. Because the images must be interpreted by a medical expert, it is infeasible to screen all…

Computer Vision and Pattern Recognition · Computer Science 2024-10-07 Andrea M. Storås , Josefine V. Sundgaard

The quality of diabetic retinopathy (DR) screening relies on the ability to correctly grade severity; however, many deep-learning (DL) classifiers cannot be easily interpreted in the clinical context. This study presents a methodology that…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Pir Bakhsh Khokhar , Carmine Gravino , Fabio Palomba , Sule Yildirim Yayilgan , Sarang Shaikh

Decisions made by convolutional neural networks(CNN) can be understood and explained by visualizing discriminative regions on images. To this end, Class Activation Map (CAM) based methods were proposed as powerful interpretation tools,…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Yi Liao , Yongsheng Gao , Weichuan Zhang

Accurate staging of Diabetic Retinopathy (DR) is essential for guiding timely interventions and preventing vision loss. However, current staging models are hardly interpretable, and most public datasets contain no clinical reasoning or…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Chenjun Li , Laurin Lux , Alexander H. Berger , Martin J. Menten , Mert R. Sabuncu , Johannes C. Paetzold
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