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Deep neural networks (DNN) have been used successfully in many scientific problems for their high prediction accuracy, but their application to genetic studies remains challenging due to their poor interpretability. In this paper, we…

Machine Learning · Computer Science 2021-10-01 Peyman H. Kassani , Fred Lu , Yann Le Guen , Zihuai He

Attribution methods calculate attributions that visually explain the predictions of deep neural networks (DNNs) by highlighting important parts of the input features. In particular, gradient-based attribution (GBA) methods are widely used…

Machine Learning · Computer Science 2021-02-16 Jae-Hong Lee , Joon-Hyuk Chang

Neural networks (NNs) achieve outstanding performance in many domains; however, their decision processes are often opaque and their inference can be computationally expensive in resource-constrained environments. We recently proposed…

Machine Learning · Computer Science 2025-05-30 Chang Yue , Niraj K. Jha

The ubiquity of neural networks (NNs) in real-world applications, from healthcare to natural language processing, underscores their immense utility in capturing complex relationships within high-dimensional data. However, NNs come with…

Machine Learning · Computer Science 2024-07-08 Chang Yue , Niraj K. Jha

Point cloud data is ubiquitous in scientific fields. Recently, geometric deep learning (GDL) has been widely applied to solve prediction tasks with such data. However, GDL models are often complicated and hardly interpretable, which poses…

Machine Learning · Computer Science 2023-03-03 Siqi Miao , Yunan Luo , Mia Liu , Pan Li

Convolutional Neural Networks (CNN) have become de fact state-of-the-art for the main computer vision tasks. However, due to the complex underlying structure their decisions are hard to understand which limits their use in some context of…

Computer Vision and Pattern Recognition · Computer Science 2021-07-02 Nina Schaaf , Omar de Mitri , Hang Beom Kim , Alexander Windberger , Marco F. Huber

Ensuring the trustworthiness and interpretability of machine learning models is critical to their deployment in real-world applications. Feature attribution methods have gained significant attention, which provide local explanations of…

Machine Learning · Computer Science 2023-09-20 Md Abdul Kadir , Gowtham Krishna Addluri , Daniel Sonntag

Complex nonlinear models such as deep neural network (DNNs) have become an important tool for image classification, speech recognition, natural language processing, and many other fields of application. These models however lack…

Graph Neural Networks (GNNs) are a popular approach for predicting graph structured data. As GNNs tightly entangle the input graph into the neural network structure, common explainable AI approaches are not applicable. To a large extent,…

Explainable AI (XAI) methods help identify which image regions influence a model's prediction, but often face a trade-off between detail and interpretability. Layer-wise Relevance Propagation (LRP) offers a model-aware alternative. However,…

Machine Learning · Computer Science 2025-10-02 Emerald Zhang , Julian Weaver , Samantha R Santacruz , Edward Castillo

Deep neural networks are very successful on many vision tasks, but hard to interpret due to their black box nature. To overcome this, various post-hoc attribution methods have been proposed to identify image regions most influential to the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Sukrut Rao , Moritz Böhle , Bernt Schiele

Text documents can be described by a number of abstract concepts such as semantic category, writing style, or sentiment. Machine learning (ML) models have been trained to automatically map documents to these abstract concepts, allowing to…

Computation and Language · Computer Science 2017-11-01 Leila Arras , Franziska Horn , Grégoire Montavon , Klaus-Robert Müller , Wojciech Samek

A key task in actuarial modelling involves modelling the distributional properties of losses. Classic (distributional) regression approaches like Generalized Linear Models (GLMs; Nelder and Wedderburn, 1972) are commonly used, but…

Machine Learning · Statistics 2024-06-04 Benjamin Avanzi , Eric Dong , Patrick J. Laub , Bernard Wong

Machine learning-based imaging diagnostics has recently reached or even superseded the level of clinical experts in several clinical domains. However, classification decisions of a trained machine learning system are typically…

Attributing the output of a neural network to the contribution of given input elements is a way of shedding light on the black-box nature of neural networks. Due to the complexity of current network architectures, current gradient-based…

Computer Vision and Pattern Recognition · Computer Science 2020-03-10 Ashkan Khakzar , Soroosh Baselizadeh , Saurabh Khanduja , Christian Rupprecht , Seong Tae Kim , Nassir Navab

We present an application of the Layer-wise Relevance Propagation (LRP) algorithm to state of the art deep convolutional neural networks and Fisher Vector classifiers to compare the image perception and prediction strategies of both…

Computer Vision and Pattern Recognition · Computer Science 2016-04-05 Sebastian Bach , Alexander Binder , Klaus-Robert Müller , Wojciech Samek

Neural network models have achieved state-of-the-art performances in a wide range of natural language processing (NLP) tasks. However, a long-standing criticism against neural network models is the lack of interpretability, which not only…

Computation and Language · Computer Science 2021-10-26 Xiaofei Sun , Diyi Yang , Xiaoya Li , Tianwei Zhang , Yuxian Meng , Han Qiu , Guoyin Wang , Eduard Hovy , Jiwei Li

We show that utilizing attribution maps for training neural networks can improve regularization of models and thus increase performance. Regularization is key in deep learning, especially when training complex models on relatively small…

Machine Learning · Computer Science 2022-05-31 Christian Tomani , Daniel Cremers

Fully Connected Neural Networks (FCNNs) are often regarded as simple and intuitive architectures, yet they serve as the foundation for more complex models. Nonetheless, the lack of consensus on their interpretability continues to pose…

Machine Learning · Computer Science 2026-05-18 Thodoris Lymperopoulos , Denia Kanellopoulou

While deep neural networks (DNN) have become an effective computational tool, the prediction results are often criticized by the lack of interpretability, which is essential in many real-world applications such as health informatics.…

Computer Vision and Pattern Recognition · Computer Science 2018-05-29 Mengnan Du , Ninghao Liu , Qingquan Song , Xia Hu