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The detection of clinically significant prostate cancer lesions (csPCa) from biparametric magnetic resonance imaging (bp-MRI) has emerged as a noninvasive imaging technique for improving accurate diagnosis. Nevertheless, the analysis of…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Mateo Ortiz , Juan Olmos , Fabio Martínez

Biparametric magnetic resonance imaging (bpMRI) has demonstrated promising results in prostate cancer (PCa) detection using convolutional neural networks (CNNs). Recently, transformers have achieved competitive performance compared to CNNs…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Yuheng Li , Jacob Wynne , Jing Wang , Richard L. J. Qiu , Justin Roper , Shaoyan Pan , Ashesh B. Jani , Tian Liu , Pretesh R. Patel , Hui Mao , Xiaofeng Yang

Magnetic Resonance Imaging (MRI) is vital for prostate cancer (PCa) diagnosis. While advanced techniques such as Hybrid Multi-dimensional MRI (HM-MRI) have enhanced diagnostic capabilities, the significant need remains for robust, automated…

Biparametric MRI has emerged as an alternative to multiparametric prostate MRI, which eliminates the need for the potential harms to the patient due to the contrast medium. One major issue with biparametric MRI is difficulty to detect…

Multi-parametric magnetic resonance imaging (mpMRI) has a growing role in detecting prostate cancer lesions. Thus, it is pertinent that medical professionals who interpret these scans reduce the risk of human error by using computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2022-08-25 Haoli Yin , Nithin Buduma

We hypothesize that anatomical priors can be viable mediums to infuse domain-specific clinical knowledge into state-of-the-art convolutional neural networks (CNN) based on the U-Net architecture. We introduce a probabilistic population…

Image and Video Processing · Electrical Eng. & Systems 2021-09-22 Anindo Saha , Matin Hosseinzadeh , Henkjan Huisman

We present a multi-stage 3D computer-aided detection and diagnosis (CAD) model for automated localization of clinically significant prostate cancer (csPCa) in bi-parametric MR imaging (bpMRI). Deep attention mechanisms drive its detection…

Image and Video Processing · Electrical Eng. & Systems 2021-07-02 Anindo Saha , Matin Hosseinzadeh , Henkjan Huisman

Fully supervised deep models have shown promising performance for many medical segmentation tasks. Still, the deployment of these tools in clinics is limited by the very timeconsuming collection of manually expert-annotated data. Moreover,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Robin Trombetta , Olivier Rouvière , Carole Lartizien

Purpose: We aimed to develop deep machine learning (DL) models to improve the detection and segmentation of intraprostatic lesions (IL) on bp-MRI by using whole amount prostatectomy specimen-based delineations. We also aimed to investigate…

Image and Video Processing · Electrical Eng. & Systems 2020-10-30 Zhenzhen Dai , Ivan Jambor , Pekka Taimen , Milan Pantelic , Mohamed Elshaikh , Craig Rogers , Otto Ettala , Peter Boström , Hannu Aronen , Harri Merisaari , Ning Wen

We propose and evaluate a novel method for automatically detecting clinically significant prostate cancer (csPCa) in bi-parametric magnetic resonance imaging (bpMRI). Prostate zones play an important role in the assessment of prostate…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Matin Hosseinzadeh , Patrick Brand , Henkjan Huisman

Prostate cancer is the most common cancer among US men. However, prostate imaging is still challenging despite the advances in multi-parametric Magnetic Resonance Imaging (MRI), which provides both morphologic and functional information…

Automatic segmentation of medical images with DL algorithms has proven to be highly successful. With most of these algorithms, inter-observer variation is an acknowledged problem, leading to sub-optimal results. This problem is even more…

Computer Vision and Pattern Recognition · Computer Science 2021-02-17 Anjali Balagopal , Howard Morgan , Michael Dohopoloski , Ramsey Timmerman , Jie Shan , Daniel F. Heitjan , Wei Liu , Dan Nguyen , Raquibul Hannan , Aurelie Garant , Neil Desai , Steve Jiang

Prostate cancer (PCa) is a severe disease among men globally. It is important to identify PCa early and make a precise diagnosis for effective treatment. For PCa diagnosis, Multi-parametric magnetic resonance imaging (mpMRI) emerged as an…

Image and Video Processing · Electrical Eng. & Systems 2023-10-11 Anil B. Gavade , Neel Kanwal , Priyanka A. Gavade , Rajendra Nerli

Quality of deep convolutional neural network predictions strongly depends on the size of the training dataset and the quality of the annotations. Creating annotations, especially for 3D medical image segmentation, is time-consuming and…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Matin Hosseinzadeh , Anindo Saha , Joeran Bosma , Henkjan Huisman

Pre-biopsy magnetic resonance imaging (MRI) is increasingly used to target suspicious prostate lesions. This has led to artificial intelligence (AI) applications improving MRI-based detection of clinically significant prostate cancer…

Image and Video Processing · Electrical Eng. & Systems 2025-02-04 Hassan Jahanandish , Shengtian Sang , Cynthia Xinran Li , Sulaiman Vesal , Indrani Bhattacharya , Jeong Hoon Lee , Richard Fan , Geoffrey A. Sonna , Mirabela Rusu

Prostate cancer (PCa) is the most prevalent cancer among men in the United States, accounting for nearly 300,000 cases, 29\% of all diagnoses and 35,000 total deaths in 2024. Traditional screening methods such as prostate-specific antigen…

Image and Video Processing · Electrical Eng. & Systems 2025-05-27 Jarett Dewbury , Chi-en Amy Tai , Alexander Wong

The emergence of multi-parametric magnetic resonance imaging (mpMRI) has had a profound impact on the diagnosis of prostate cancers (PCa), which is the most prevalent malignancy in males in the western world, enabling a better selection of…

Prostate cancer is a commonly diagnosed cancerous disease among men world-wide. Even with modern technology such as multi-parametric magnetic resonance tomography and guided biopsies, the process for diagnosing prostate cancer remains time…

Image and Video Processing · Electrical Eng. & Systems 2024-04-17 Malte Rippa , Ruben Schulze , Marian Himstedt , Felice Burn

While current research has shown the importance of Multi-parametric MRI (mpMRI) in diagnosing prostate cancer (PCa), further investigation is needed for how to incorporate the specific structures of the mpMRI data, such as the regional…

Machine Learning · Statistics 2021-11-04 Jin Jin , Lin Zhang , Ethan Leng , Gregory J. Metzger , Joseph S. Koopmeiners

Purpose: The scarcity of high-quality curated labeled medical training data remains one of the major limitations in applying artificial intelligence (AI) systems to breast cancer diagnosis. Deep models for mammogram analysis and mass (or…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Han Chen , Anne L. Martel
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