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The variation in DNA copy number carries information on the modalities of genome evolution and misregulation of DNA replication in cancer cells; its study can be helpful to localize tumor suppressor genes, distinguish different populations…

Methodology · Statistics 2012-03-20 Zhongyang Zhang , Kenneth Lange , Chiara Sabatti

Malicious software are categorized into families based on their static and dynamic characteristics, infection methods, and nature of threat. Visual exploration of malware instances and families in a low dimensional space helps in giving a…

Cryptography and Security · Computer Science 2019-01-31 Mohamed Nassar , Haidar Safa

This paper introduces a new family of reconstruction codes which is motivated by applications in DNA data storage and sequencing. In such applications, DNA strands are sequenced by reading some subset of their substrings. While previous…

Information Theory · Computer Science 2022-05-10 Yonatan Yehezkeally , Daniella Bar-Lev , Sagi Marcovich , Eitan Yaakobi

Magnetic Resonance Imaging (MRI) of the brain has been used to investigate a wide range of neurological disorders, but data acquisition can be expensive, time-consuming, and inconvenient. Multi-site studies present a valuable opportunity to…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Harrison Nguyen , Richard W. Morris , Anthony W. Harris , Mayuresh S. Korgoankar , Fabio Ramos

The ability to encode and manipulate data structures with distributed neural representations could qualitatively enhance the capabilities of traditional neural networks by supporting rule-based symbolic reasoning, a central property of…

Computer Vision and Pattern Recognition · Computer Science 2020-07-09 E. Paxon Frady , Spencer Kent , Bruno A. Olshausen , Friedrich T. Sommer

Human vision involves parsing and representing objects and scenes using structured representations based on part-whole hierarchies. Computer vision and machine learning researchers have recently sought to emulate this capability using…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Ares Fisher , Rajesh P. N. Rao

Autonomous systems (AS) often use Deep Neural Network (DNN) classifiers to allow them to operate in complex, high-dimensional, non-linear, and dynamically changing environments. Due to the complexity of these environments, DNN classifiers…

Machine Learning · Computer Science 2024-08-16 Abanoub Ghobrial , Xuan Zheng , Darryl Hond , Hamid Asgari , Kerstin Eder

Deep neural networks (DNNs) are a contemporary solution for semantic segmentation and are usually trained to operate on a predefined closed set of classes. In open-set environments, it is possible to encounter semantically unknown objects…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Jurica Runtas , Tomislav Petkovic

In this paper we study the structure of specific linear codes called DNA codes. The first attempts on studying such codes have been proposed over four element rings which are naturally matched with DNA four letters. Later, double (pair) DNA…

Combinatorics · Mathematics 2017-03-31 Fatmanur Gürsoy , Elif Segah Oztas , Irfan Siap

Self-replication is a key aspect of biological life that has been largely overlooked in Artificial Intelligence systems. Here we describe how to build and train self-replicating neural networks. The network replicates itself by learning to…

Artificial Intelligence · Computer Science 2018-05-28 Oscar Chang , Hod Lipson

Since convolutional neural network (CNN) lacks an inherent mechanism to handle large scale variations, we always need to compute feature maps multiple times for multi-scale object detection, which has the bottleneck of computational cost in…

Computer Vision and Pattern Recognition · Computer Science 2018-02-09 Yu Liu , Hongyang Li , Junjie Yan , Fangyin Wei , Xiaogang Wang , Xiaoou Tang

Metamorphic viruses are considered the most dangerous of all computer viruses. Unlike other computer viruses that can be detected statically using static signature technique or dynamically using emulators, metamorphic viruses change their…

Cryptography and Security · Computer Science 2013-12-17 Moustafa Saleh

Identifying mutations of SARS-CoV-2 strains associated with their phenotypic changes is critical for pandemic prediction and prevention. We compared an explainable convolutional neural network (CNN) approach and the traditional genome-wide…

Genomics · Quantitative Biology 2025-01-03 Parisa Hatami , Richard Annan , Luis Urias Miranda , Jane Gorman , Mengjun Xie , Letu Qingge , Hong Qin

Cyclic patterns of neuronal activity are ubiquitous in animal nervous systems, and partially responsible for generating and controlling rhythmic movements such as locomotion, respiration, swallowing and so on. Clarifying the role of the…

Neural and Evolutionary Computing · Computer Science 2013-08-26 Chuan Zhang , Gerhard Dangelmayr , Iuliana Oprea

For the vast majority of genome wide association studies (GWAS) published so far, statistical analysis was performed by testing markers individually. In this article we present some elementary statistical considerations which clearly show…

Applications · Statistics 2010-10-04 Florian Frommlet , Felix Ruhaltinger , Piotr Twarog , Malgorzata Bogdan

Generative adversarial networks (GANs) are one powerful type of deep learning models that have been successfully utilized in numerous fields. They belong to a broader family called generative methods, which generate new data with a…

We introduce the Genetic-Gated Networks (G2Ns), simple neural networks that combine a gate vector composed of binary genetic genes in the hidden layer(s) of networks. Our method can take both advantages of gradient-free optimization and…

Neural and Evolutionary Computing · Computer Science 2019-03-06 Simyung Chang , John Yang , Jaeseok Choi , Nojun Kwak

Correct inference of genetic regulations inside a cell is one of the greatest challenges in post genomic era for the biologist and researchers. Several intelligent techniques and models were already proposed to identify the regulatory…

Artificial Intelligence · Computer Science 2017-08-03 Sudip Mandal , Goutam Saha , Rajat K. Pal

In spite of intense research efforts, deep neural networks remain vulnerable to adversarial examples: an input that forces the network to confidently produce incorrect outputs. Adversarial examples are typically generated by an attack…

Artificial Intelligence · Computer Science 2023-02-02 David Aaron Nicholson , Vincent Emanuele

Network biology has been successfully used to help reveal complex mechanisms of disease, especially cancer. On the other hand, network biology requires in-depth knowledge to construct disease-specific networks, but our current knowledge is…

Computer Vision and Pattern Recognition · Computer Science 2018-06-18 Sungmin Rhee , Seokjun Seo , Sun Kim