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We introduce a statistical procedure that integrates survival data from multiple biomedical studies, to improve the accuracy of predictions of survival or other events, based on individual clinical and genomic profiles, compared to models…

Applications · Statistics 2020-07-20 Steffen Ventz , Rahul Mazumder , Lorenzo Trippa

There has been increasing concern within the machine learning community that we are in a reproducibility crisis. As many have begun to work on this problem, all work we are aware of treat the issue of reproducibility as an intrinsic binary…

Machine Learning · Statistics 2020-12-21 Edward Raff

Background Study individuals may face repeated events overtime. However, there is no consensus around learning approaches to use in a high-dimensional framework for survival data (when the number of variables exceeds the number of…

Methodology · Statistics 2022-03-30 Juliette Murris , Anais Charles-Nelson , Audrey Lavenu , Sandrine Katsahian

The methodological advancements made in the field of joint models are numerous. None the less, the case of competing risks joint models have largely been neglected, especially from a practitioner's point of view. In the relevant works on…

Methodology · Statistics 2019-09-05 Janet van Niekerk , Haakon Bakka , Haavard Rue

Discrimination and calibration represent two important properties of survival analysis, with the former assessing the model's ability to accurately rank subjects and the latter evaluating the alignment of predicted outcomes with actual…

Machine Learning · Computer Science 2024-06-04 Shi-ang Qi , Yakun Yu , Russell Greiner

As machine learning has become increasingly popular over the last few decades, so too has the number of machine learning interfaces for implementing these models. Whilst many R libraries exist for machine learning, very few offer extended…

Computation · Statistics 2021-03-19 Raphael Sonabend , Franz J. Király , Andreas Bender , Bernd Bischl , Michel Lang

In this paper, we explore a method for treating survival analysis as a classification problem. The method uses a "stacking" idea that collects the features and outcomes of the survival data in a large data frame, and then treats it as a…

Methodology · Statistics 2019-09-27 Chenyang Zhong , Robert Tibshirani

Modeling the spread of social contagions is central to various applications in social computing. In this paper, we study the learnability of the competitive threshold model from a theoretical perspective. We demonstrate how competitive…

Machine Learning · Computer Science 2022-05-10 Yifan Wang , Guangmo Tong

This paper compares six different parameter estimation methods for shared frailty models via a series of simulation studies. A shared frailty model is a survival model that incorporates a random effect term, where the frailties are common…

Methodology · Statistics 2023-11-21 Tingxuan Wu , Cindy Feng , Longhai Li

Competing risks occur in survival analysis when multiple causes of death are present. They play a prominent role in several domains extending beyond biostatistics to encompass epidemiology, actuarial sciences, and reliability theory. This…

Methodology · Statistics 2026-04-30 Claudio Del Sole , Antonio Lijoi , Igor Prünster

Models for predicting the time of a future event are crucial for risk assessment, across a diverse range of applications. Existing time-to-event (survival) models have focused primarily on preserving pairwise ordering of estimated event…

Machine Learning · Statistics 2021-01-14 Paidamoyo Chapfuwa , Chenyang Tao , Lawrence Carin , Ricardo Henao

Algorithmic fairness is an increasingly important field concerned with detecting and mitigating biases in machine learning models. There has been a wealth of literature for algorithmic fairness in regression and classification however there…

Computers and Society · Computer Science 2022-07-25 Raphael Sonabend , Florian Pfisterer , Alan Mishler , Moritz Schauer , Lukas Burk , Sumantrak Mukherjee , Sebastian Vollmer

One of the commonly used approaches to capture dependence in multivariate survival data is through the frailty variables. The identifiability issues should be carefully investigated while modeling multivariate survival with or without…

Methodology · Statistics 2024-07-03 Biswadeep Ghosh , Anup Dewanji , Sudipta Das

Survival analysis studies time-modeling techniques for an event of interest occurring for a population. Survival analysis found widespread applications in healthcare, engineering, and social sciences. However, the data needed to train…

Machine Learning · Computer Science 2023-02-22 Alberto Archetti , Eugenio Lomurno , Francesco Lattari , André Martin , Matteo Matteucci

Various stochastic models have been proposed to estimate mortality rates. In this paper we illustrate how machine learning techniques allow us to analyze the quality of such mortality models. In addition, we present how these techniques can…

Applications · Statistics 2017-05-10 Philippe Deprez , Pavel V. Shevchenko , Mario V. Wüthrich

Competing risks models can involve more than one time scale. A relevant example is the study of mortality after a cancer diagnosis, where time since diagnosis but also age may jointly determine the hazards of death due to different causes.…

Methodology · Statistics 2024-08-28 Angela Carollo , Hein Putter , Paul H. C. Eilers , Jutta Gampe

Advancements in medical informatics tools and high-throughput biological experimentation make large-scale biomedical data routinely accessible to researchers. Competing risks data are typical in biomedical studies where individuals are at…

Computation · Statistics 2021-11-30 Eric S Kawaguchi , Jenny I Shen , Gang Li , Marc A Suchard

Survival analysis is a hotspot in statistical research for modeling time-to-event information with data censorship handling, which has been widely used in many applications such as clinical research, information system and other fields with…

Machine Learning · Computer Science 2018-11-14 Kan Ren , Jiarui Qin , Lei Zheng , Zhengyu Yang , Weinan Zhang , Lin Qiu , Yong Yu

Balanced representation learning methods have been applied successfully to counterfactual inference from observational data. However, approaches that account for survival outcomes are relatively limited. Survival data are frequently…

Machine Learning · Statistics 2021-03-04 Paidamoyo Chapfuwa , Serge Assaad , Shuxi Zeng , Michael J. Pencina , Lawrence Carin , Ricardo Henao

There has been a significant increase in the development of data-driven safety analytics approaches in recent years. In light of these advances it has become imperative to evaluate such approaches in a principled way to determine their…

Applications · Statistics 2022-05-02 Antonio R. Paiva , Ashutosh Tewari