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Estimating multi-component T2 relaxation distributions from Multi-Echo Spin Echo (MESE) MRI is a severely ill-posed inverse problem, traditionally solved using regularized non-negative least squares (NNLS). In abdominal imaging,…

Machine Learning · Computer Science 2026-03-17 Hadas Ben Atya , Nicole Abramenkov , Noa Mashiah , Luise Brock , Daphna Link Sourani , Ram Weiss , Moti Freiman

Recovering the T2 distribution from multi-echo T2 magnetic resonance (MR) signals is challenging but has high potential as it provides biomarkers characterizing the tissue micro-structure, such as the myelin water fraction (MWF). In this…

We present a microstructure imaging technique for estimating compartment-specific T2 and T2* simultaneously in the human brain. Microstructure imaging with diffusion MRI (dMRI) has enabled the modelling of intra-neurite and extra-neurite…

Medical Physics · Physics 2024-08-21 Ting Gong , Merlin J. Fair , Kawin Setsompop , Hui Zhang

Physics-Informed Neural Networks (PINN) are emerging as a promising approach for quantitative parameter estimation of Magnetic Resonance Imaging (MRI). While existing deep learning methods can provide an accurate quantitative estimation of…

We propose a deep learning-based approach that integrates MRI sequence parameters to improve the accuracy and generalizability of quantitative image synthesis from clinical weighted MRI. Our physics-driven neural network embeds MRI sequence…

Image and Video Processing · Electrical Eng. & Systems 2025-08-12 Lingjing Chen , Chengxiu Zhang , Yinqiao Yi , Yida Wang , Yang Song , Xu Yan , Shengfang Xu , Dalin Zhu , Mengqiu Cao , Yan Zhou , Chenglong Wang , Guang Yang

Magnetic resonance imaging (MRI) offers superior soft tissue contrast and is widely used in biomedicine. However, conventional MRI is not quantitative, which presents a bottleneck in image analysis and digital healthcare. Typically,…

Deep neural networks (DNNs) offer significant promise for improving breast cancer diagnosis in medical imaging. However, these models are highly susceptible to adversarial attacks--small, imperceptible changes that can mislead…

Computer Vision and Pattern Recognition · Computer Science 2024-12-16 Yasamin Medghalchi , Moein Heidari , Clayton Allard , Leonid Sigal , Ilker Hacihaliloglu

We propose a novel automatic method for accurate segmentation of the prostate in T2-weighted magnetic resonance imaging (MRI). Our method is based on convolutional neural networks (CNNs). Because of the large variability in the shape, size,…

Image and Video Processing · Electrical Eng. & Systems 2020-01-01 Davood Karimi , Golnoosh Samei , Yanan Shao , Septimiu Salcudean

Traditional neural network regression models provide only point estimates, failing to capture predictive uncertainty. Probabilistic neural networks (PNNs) address this limitation by producing output distributions, enabling the construction…

Machine Learning · Computer Science 2026-03-02 Farhad Pourkamali-Anaraki

Multiple sclerosis is one of the most common chronic neurological diseases affecting the central nervous system. Lesions produced by the MS can be observed through two modalities of magnetic resonance (MR), known as T2W and FLAIR sequences,…

Signal Processing · Electrical Eng. & Systems 2022-12-16 Antonio Falvo , Danilo Comminiello , Simone Scardapane , Michele Scarpiniti , Aurelio Uncini

Magnetic resonance imaging (MRI) is a cornerstone of clinical neuroimaging, yet conventional MRIs provide qualitative information heavily dependent on scanner hardware and acquisition settings. While quantitative MRI (qMRI) offers intrinsic…

T2 mapping in fetal brain MRI has the potential to improve characterization of the developing brain, especially at mid-field (0.55T), where T2 decay is slower. However, this is challenging as fetal MRI acquisition relies on multiple…

Purpose: An end-to-end deep convolutional neural network (CNN) based on deep residual network (ResNet) was proposed to efficiently reconstruct reliable T2 mapping from single-shot OverLapping-Echo Detachment (OLED) planar imaging. Methods:…

Computer Vision and Pattern Recognition · Computer Science 2017-08-18 Congbo Cai , Yiqing Zeng , Chao Wang , Shuhui Cai , Jun Zhang , Zhong Chen , Xinghao Ding , Jianhui Zhong

We introduce interlaced R2D2 (iR2D2), a DNN series paradigm for scalable image reconstruction from accelerated non-Cartesian k-space acquisitions in MRI with sensitivity map self-calibration. While unrolled DNN architectures provide robust…

Image and Video Processing · Electrical Eng. & Systems 2026-05-05 Shijie Chen , Yiwei Chen , Amir Aghabiglou , Motahare Torki , Chao Tang , Ruud B. van Heeswijk , Yves Wiaux

Realizing complete observability in the three-phase distribution system remains a challenge that hinders the implementation of classic state estimation algorithms. In this paper, a new method, called the pruned physics-aware neural network…

Systems and Control · Electrical Eng. & Systems 2021-10-18 Minh-Quan Tran , Ahmed S. Zamzam , Phuong H. Nguyen

A model-based reconstruction technique for accelerated T2 mapping with improved accuracy is proposed using undersampled Cartesian spin-echo MRI data. The technique employs an advanced signal model for T2 relaxation that accounts for…

Medical Physics · Physics 2015-03-03 Tilman J. Sumpf , Andreas Petrovic , Martin Uecker , Florian Knoll , Jens Frahm

Accurate automatic segmentation of brain anatomy from $T_1$-weighted~($T_1$-w) magnetic resonance images~(MRI) has been a computationally intensive bottleneck in neuroimaging pipelines, with state-of-the-art results obtained by unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2018-08-01 Amod Jog , Bruce Fischl

Large language models (LLMs) face significant deployment challenges due to their massive computational demands. % While pruning offers a promising compression solution, existing methods suffer from two critical limitations: (1) They neglect…

Machine Learning · Computer Science 2026-04-01 Lang Xiong , Ning Liu , Ao Ren , Yuheng Bai , Haining Fang , BinYan Zhang , Zhe Jiang , Yujuan Tan , Duo Liu

Quantitative MRI (qMRI) offers significant advantages over weighted images by providing objective parameters related to tissue properties. Deep learning-based methods have demonstrated effectiveness in estimating quantitative maps from…

Computer Vision and Pattern Recognition · Computer Science 2024-10-15 Shishuai Wang , Hua Ma , Juan A. Hernandez-Tamames , Stefan Klein , Dirk H. J. Poot

Diffusion tensor imaging (DTI) holds significant importance in clinical diagnosis and neuroscience research. However, conventional model-based fitting methods often suffer from sensitivity to noise, leading to decreased accuracy in…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Jialong Li , Zhicheng Zhang , Yunwei Chen , Qiqi Lu , Ye Wu , Xiaoming Liu , QianJin Feng , Yanqiu Feng , Xinyuan Zhang
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