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Alzheimer's disease is a progressive neurodegenerative disorder that remains challenging to predict due to its multifactorial etiology and the complexity of multimodal clinical data. Accurate forecasting of clinically relevant biomarkers,…

Machine Learning · Computer Science 2026-02-03 Yilang Ding , Jiawen Ren , Jiaying Lu , Gloria Hyunjung Kwak , Armin Iraji , Shengpu Tang , Alex Fedorov

Introduction: Alzheimer's disease is a type of dementia in which early diagnosis plays a major rule in the quality of treatment. Among new works in the diagnosis of Alzheimer's disease, there are many of them analyzing the voice stream…

Machine Learning · Computer Science 2019-10-02 S. Soroush Haj Zargarbashi , Bagher Babaali

Generating realistic images to accurately predict changes in the structure of brain MRI is a crucial tool for clinicians. Such applications help assess patients' outcomes and analyze how diseases progress at the individual level. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-06-19 Mattia Litrico , Francesco Guarnera , Valerio Giuffirda , Daniele Ravì , Sebastiano Battiato

Human visual attention is a complex phenomenon that has been studied for decades. Within it, the particular problem of scanpath prediction poses a challenge, particularly due to the inter- and intra-observer variability, among other…

Computer Vision and Pattern Recognition · Computer Science 2022-04-21 Daniel Martin , Diego Gutierrez , Belen Masia

Deep learning algorithms for predicting neuroimaging data have shown considerable promise in various applications. Prior work has demonstrated that deep learning models that take advantage of the data's 3D structure can outperform standard…

Image and Video Processing · Electrical Eng. & Systems 2023-03-07 Yuda Bi , Anees Abrol , Zening Fu , Jiayu Chen , Jingyu Liu , Vince Calhoun

The most frequent kind of dementia of the nervous system, Alzheimer's disease, weakens several brain processes (such as memory) and eventually results in death. The clinical study uses magnetic resonance imaging to diagnose AD. Deep…

Image and Video Processing · Electrical Eng. & Systems 2023-10-30 Sarasadat Foroughipoor , Kimia Moradi , Hamidreza Bolhasani

The hippocampal formation is thought to learn spatial maps of environments, and in many models this learning process consists of forming a sensory association for each location in the environment. This is inefficient, akin to learning a…

Artificial Intelligence · Computer Science 2021-07-02 Marcus Lewis

In recent years, with the continuous advancement of deep learning and the emergence of large-scale human motion datasets, human motion prediction technology has gradually gained prominence in various fields such as human-computer…

Computer Vision and Pattern Recognition · Computer Science 2023-12-12 Tenghao Deng , Yan Sun

Although Alzheimer's disease detection via MRIs has advanced significantly thanks to contemporary deep learning models, challenges such as class imbalance, protocol variations, and limited dataset diversity often hinder their generalization…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Zobia Batool , Huseyin Ozkan , Erchan Aptoula

Analyzing and predicting brain aging is essential for early prognosis and accurate diagnosis of cognitive diseases. The technique of neuroimaging, such as Magnetic Resonance Imaging (MRI), provides a noninvasive means of observing the aging…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Jingru Fu , Antonios Tzortzakakis , José Barroso , Eric Westman , Daniel Ferreira , Rodrigo Moreno

Prognostic models aim to predict the future course of a disease or condition and are a vital component of personalized medicine. Statistical models make use of longitudinal data to capture the temporal aspect of disease progression;…

Machine Learning · Computer Science 2020-07-13 Joshua Bridge , Simon P. Harding , Yalin Zheng

Age is one of the major known risk factors for Alzheimer's Disease (AD). Detecting AD early is crucial for effective treatment and preventing irreversible brain damage. Brain age, a measure derived from brain imaging reflecting structural…

Image and Video Processing · Electrical Eng. & Systems 2024-05-07 Jay Shah , Md Mahfuzur Rahman Siddiquee , Yi Su , Teresa Wu , Baoxin Li

Deep learning has become an important tool for Alzheimer's disease (AD) classification from structural MRI. Many existing studies analyze individual 2D slices extracted from MRI volumes, while clinical neuroimaging practice typically relies…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Md Sifat , Sania Akter , Akif Islam , Md. Ekramul Hamid , Abu Saleh Musa Miah , Najmul Hassan , Md Abdur Rahim , Jungpil Shin

We introduce a novel approach for predicting the progression of adolescent idiopathic scoliosis from 3D spine models reconstructed from biplanar X-ray images. Recent progress in machine learning have allowed to improve classification and…

Machine Learning · Computer Science 2017-01-25 Samuel Kadoury , William Mandel , Marjolaine Roy-Beaudry , Marie-Lyne Nault , Stefan Parent

Aortic shape analysis plays a key role in cardiovascular diagnostics, treatment planning, and understanding disease progression. We present a robust, fully automated pipeline for aortic shape analysis from cardiac MRI, combining deep…

Tissues and Organs · Quantitative Biology 2025-09-15 Nairouz Shehata , Amr Elsawy , Mohamed Nagy , Muhammad ElMahdy , Mariam Ali , Soha Romeih , Heba Aguib , Magdi Yacoub , Ben Glocker

In recent years, manifold learning has become increasingly popular as a tool for performing non-linear dimensionality reduction. This has led to the development of numerous algorithms of varying degrees of complexity that aim to recover man…

Machine Learning · Statistics 2013-06-03 Dominique Perraul-Joncas , Marina Meila

Identifying and utilising various biomarkers for tracking Alzheimer's disease (AD) progression have received many recent attentions and enable helping clinicians make the prompt decisions. Traditional progression models focus on extracting…

Machine Learning · Computer Science 2023-11-08 Xulong Wang , Yu Zhang , Menghui Zhou , Tong Liu , Jun Qi , Po Yang

We propose a statistical modeling technique, called the Hierarchical Association Rule Model (HARM), that predicts a patient's possible future medical conditions given the patient's current and past history of reported conditions. The core…

Applications · Statistics 2012-06-29 Tyler H. McCormick , Cynthia Rudin , David Madigan

Brain imaging has allowed neuroscientists to analyze brain morphology in genetic and neurodevelopmental disorders, such as Down syndrome, pinpointing regions of interest to unravel the neuroanatomical underpinnings of cognitive impairment…

Computer Vision and Pattern Recognition · Computer Science 2024-09-23 Jordi Malé , Juan Fortea , Mateus Rozalem Aranha , Yann Heuzé , Neus Martínez-Abadías , Xavier Sevillano

Tissue loss in the hippocampi has been heavily correlated with the progression of Alzheimer's Disease (AD). The shape and structure of the hippocampus are important factors in terms of early AD diagnosis and prognosis by clinicians.…

Image and Video Processing · Electrical Eng. & Systems 2022-03-03 Lukas Folle , Sulaiman Vesal , Nishant Ravikumar , Andreas Maier
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