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Related papers: Is Bio-Inspired Learning Better than Backprop? Ben…

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Our brain consists of biological neurons encoding information through accurate spike timing, yet both the architecture and learning rules of our brain remain largely unknown. Comparing to the recent development of backpropagation-based…

Neural and Evolutionary Computing · Computer Science 2021-11-29 Yukun Yang , Peng Li

Backpropagation (BP) remains the dominant and most successful method for training parameters of deep neural network models. However, BP relies on two computationally distinct phases, does not provide a satisfactory explanation of biological…

Machine Learning · Computer Science 2025-11-12 Sander Dalm , Marcel van Gerven , Nasir Ahmad

The development of biologically-plausible learning algorithms is important for understanding learning in the brain, but most of them fail to scale-up to real-world tasks, limiting their potential as explanations for learning by real brains.…

Neural and Evolutionary Computing · Computer Science 2022-02-01 Maxence Ernoult , Fabrice Normandin , Abhinav Moudgil , Sean Spinney , Eugene Belilovsky , Irina Rish , Blake Richards , Yoshua Bengio

How the brain performs credit assignment is a fundamental unsolved problem in neuroscience. Many `biologically plausible' algorithms have been proposed, which compute gradients that approximate those computed by backpropagation (BP), and…

Machine Learning · Computer Science 2022-08-05 Beren Millidge , Yuhang Song , Tommaso Salvatori , Thomas Lukasiewicz , Rafal Bogacz

Empowered by the backpropagation (BP) algorithm, deep neural networks have dominated the race in solving various cognitive tasks. The restricted training pattern in the standard BP requires end-to-end error propagation, causing large memory…

Machine Learning · Computer Science 2022-05-17 Wenzhe Guo , Mohammed E Fouda , Ahmed M. Eltawil , Khaled N. Salama

Continual learning remains a fundamental challenge in artificial intelligence, with catastrophic forgetting posing a significant barrier to deploying neural networks in dynamic environments. Inspired by biological memory consolidation…

Machine Learning · Computer Science 2025-12-19 Goutham Nalagatla , Shreyas Grandhe

Back-propagation algorithm is one of the most widely used and popular techniques to optimize the feed forward neural network training. Nature inspired meta-heuristic algorithms also provide derivative-free solution to optimize complex…

Neural and Evolutionary Computing · Computer Science 2012-09-13 Sudarshan Nandy , Partha Pratim Sarkar , Achintya Das

Traditional backpropagation of error, though a highly successful algorithm for learning in artificial neural network models, includes features which are biologically implausible for learning in real neural circuits. An alternative called…

Machine Learning · Computer Science 2020-11-06 Nasir Ahmad , Marcel A. J. van Gerven , Luca Ambrogioni

Backpropagation is the foundational algorithm for training neural networks and a key driver of deep learning's success. However, its biological plausibility has been challenged due to three primary limitations: weight symmetry, reliance on…

Neural and Evolutionary Computing · Computer Science 2025-06-05 Changze Lv , Jingwen Xu , Yiyang Lu , Xiaohua Wang , Zhenghua Wang , Zhibo Xu , Di Yu , Xin Du , Xiaoqing Zheng , Xuanjing Huang

Training recurrent neural networks is predominantly achieved via backpropagation through time (BPTT). However, this algorithm is not an optimal solution from both a biological and computational perspective. A more efficient and biologically…

Machine Learning · Computer Science 2022-10-03 Michael Hoyer , Shahram Eivazi , Sebastian Otte

How do biological systems and machine learning algorithms compare in the number of samples required to show significant improvements in completing a task? We compared the learning efficiency of in vitro biological neural networks to the…

Neurons and Cognition · Quantitative Biology 2024-05-28 Moein Khajehnejad , Forough Habibollahi , Aswin Paul , Adeel Razi , Brett J. Kagan

Since humans still outperform artificial neural networks on many tasks, drawing inspiration from the brain may help to improve current machine learning algorithms. Contrastive Hebbian Learning (CHL) and Equilibrium Propagation (EP) are…

Neural and Evolutionary Computing · Computer Science 2022-05-02 Yoshimasa Kubo , Eric Chalmers , Artur Luczak

While effective, the backpropagation (BP) algorithm exhibits limitations in terms of biological plausibility, computational cost, and suitability for online learning. As a result, there has been a growing interest in developing alternative…

Neural and Evolutionary Computing · Computer Science 2023-08-07 Yanis Bahroun , Shagesh Sridharan , Atithi Acharya , Dmitri B. Chklovskii , Anirvan M. Sengupta

Backpropagation (BP) of errors is the backbone training algorithm for artificial neural networks (ANNs). It updates network weights through gradient descent to minimize a loss function representing the mismatch between predictions and…

Machine Learning · Statistics 2025-08-13 Davide Casnici , Charlotte Frenkel , Justin Dauwels

Backpropagation has long been criticized for being biologically implausible due to its reliance on concepts that are not viable in natural learning processes. Two core issues are the weight transport and update locking problems caused by…

Machine Learning · Computer Science 2026-01-14 Katharina Flügel , Daniel Coquelin , Marie Weiel , Charlotte Debus , Achim Streit , Markus Götz

Backpropagation is the workhorse of deep learning, however, several other biologically-motivated learning rules have been introduced, such as random feedback alignment and difference target propagation. None of these methods have produced a…

Neural and Evolutionary Computing · Computer Science 2020-01-07 Daniel Jiwoong Im , Rutuja Patil , Kristin Branson

Predictive coding networks (PCNs) are an influential model for information processing in the brain. They have appealing theoretical interpretations and offer a single mechanism that accounts for diverse perceptual phenomena of the brain. On…

Machine Learning · Computer Science 2021-03-08 Tommaso Salvatori , Yuhang Song , Thomas Lukasiewicz , Rafal Bogacz , Zhenghua Xu

A feed-forward neural net with adaptable synaptic weights and fixed, zero or non-zero threshold potentials is studied, in the presence of a global feedback signal that can only have two values, depending on whether the output of the network…

Disordered Systems and Neural Networks · Physics 2009-11-10 J. Bedaux , W. A. van Leeuwen

This review explores biologically inspired learning as a model for intelligent robot control and sensing technology on the basis of specific examples. Hebbian synaptic learning is discussed as a functionally relevant model for machine…

Robotics · Computer Science 2022-02-28 Birgitta Dresp-Langley

Artificial neural networks are often interpreted as abstract models of biological neuronal networks, but they are typically trained using the biologically unrealistic backpropagation algorithm and its variants. Predictive coding has been…

Neurons and Cognition · Quantitative Biology 2024-04-25 Robert Rosenbaum