English
Related papers

Related papers: Unsupervised language models for disease variant p…

200 papers

Controlling robots through natural language is pivotal for enhancing human-robot collaboration and synthesizing complex robot behaviors. Recent works that are trained on large robot datasets show impressive generalization abilities.…

Large Language Models (LLMs) have demonstrated remarkable capabilities across various applications, fundamentally reshaping the landscape of natural language processing (NLP) research. However, recent evaluation frameworks often rely on the…

Computation and Language · Computer Science 2024-07-10 Chenyang Lyu , Minghao Wu , Alham Fikri Aji

Large language models (LLMs) have revolutionised many fields, with LLM-as-a-service (LLMSaaS) offering accessible, general-purpose solutions without costly task-specific training. In contrast to the widely studied prompt engineering for…

Computation and Language · Computer Science 2026-03-17 Md Rakibul Hasan , Yue Yao , Md Zakir Hossain , Aneesh Krishna , Imre Rudas , Shafin Rahman , Tom Gedeon

A central goal of cognitive modeling is to develop models that not only predict human behavior but also provide insight into the underlying cognitive mechanisms. While neural network models trained on large-scale behavioral data often…

Artificial Intelligence · Computer Science 2026-02-03 Jian-Qiao Zhu , Hanbo Xie , Dilip Arumugam , Robert C. Wilson , Thomas L. Griffiths

Large pre-trained vision-language models (VLMs) offer a promising approach to leveraging human language for enhancing downstream tasks. However, VLMs such as CLIP face significant limitation: its performance is highly sensitive to prompt…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Ao Li , Zongfang Liu , Xinhua Li , Jinghui Zhang , Pengwei Wang , Hu Wang

Supervisory signals have the potential to make low-dimensional data representations, like those learned by mixture and topic models, more interpretable and useful. We propose a framework for training latent variable models that explicitly…

Segmentation remains an important preprocessing step both in languages where "words" or other important syntactic/semantic units (like morphemes) are not clearly delineated by white space, as well as when dealing with continuous speech…

Computation and Language · Computer Science 2021-09-07 C. M. Downey , Fei Xia , Gina-Anne Levow , Shane Steinert-Threlkeld

This paper explores deep latent variable models for semi-supervised paraphrase generation, where the missing target pair for unlabelled data is modelled as a latent paraphrase sequence. We present a novel unsupervised model named…

Computation and Language · Computer Science 2023-09-12 Jialin Yu , Alexandra I. Cristea , Anoushka Harit , Zhongtian Sun , Olanrewaju Tahir Aduragba , Lei Shi , Noura Al Moubayed

Proteins adopt multiple structural conformations to perform their diverse biological functions, and understanding these conformations is crucial for advancing drug discovery. Traditional physics-based simulation methods often struggle with…

Biomolecules · Quantitative Biology 2025-03-14 Jiarui Lu , Xiaoyin Chen , Stephen Zhewen Lu , Chence Shi , Hongyu Guo , Yoshua Bengio , Jian Tang

Amino-acid substitutions are implicated in a wide range of human diseases, many of which are lethal. Distinguishing such mutations from polymorphisms without significant effect on human health is a necessary step in understanding the…

Quantitative Methods · Quantitative Biology 2017-01-26 Christoph Feinauer , Martin Weigt

Unsupervised learning methods have recently shown their competitiveness against supervised training. Typically, these methods use a single objective to train the entire network. But one distinct advantage of unsupervised over supervised…

Computer Vision and Pattern Recognition · Computer Science 2021-06-14 Zefan Li , Chenxi Liu , Alan Yuille , Bingbing Ni , Wenjun Zhang , Wen Gao

Conventional mechanical design follows an iterative process in which initial concepts are refined through cycles of expert assessment and resource-intensive Finite Element Method (FEM) analysis to meet performance goals. While machine…

Machine Learning · Computer Science 2025-05-02 Yayati Jadhav , Amir Barati Farimani

The functions of proteins and RNAs are determined by a myriad of interactions between their constituent residues, but most quantitative models of how molecular phenotype depends on genotype must approximate this by simple additive effects.…

Quantitative Methods · Quantitative Biology 2017-12-19 Adam J. Riesselman , John B. Ingraham , Debora S. Marks

Adapting pre-trained language models (PrLMs) (e.g., BERT) to new domains has gained much attention recently. Instead of fine-tuning PrLMs as done in most previous work, we investigate how to adapt the features of PrLMs to new domains…

Computation and Language · Computer Science 2020-12-01 Hai Ye , Qingyu Tan , Ruidan He , Juntao Li , Hwee Tou Ng , Lidong Bing

Designing protein sequences with desired biological function is crucial in biology and chemistry. Recent machine learning methods use a surrogate sequence-function model to replace the expensive wet-lab validation. How can we efficiently…

Biomolecules · Quantitative Biology 2024-12-04 Zhenqiao Song , Lei Li

Maximum likelihood estimation (MLE) is a statistical method used to estimate the parameters of a probability distribution that best explain the observed data. In the context of text generation, MLE is often used to train generative language…

Computation and Language · Computer Science 2023-10-27 Chenze Shao , Zhengrui Ma , Min Zhang , Yang Feng

With the rapid advancement of test-time compute search strategies to improve the mathematical problem-solving capabilities of large language models (LLMs), the need for building robust verifiers has become increasingly important. However,…

Computation and Language · Computer Science 2025-03-11 Jung Hyun Lee , June Yong Yang , Byeongho Heo , Dongyoon Han , Kyungsu Kim , Eunho Yang , Kang Min Yoo

Recent research suggests that Vision Language Models (VLMs) often rely on inherent biases learned during training when responding to queries about visual properties of images. These biases are exacerbated when VLMs are asked highly specific…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Saurav Sengupta , Nazanin Moradinasab , Jiebei Liu , Donald E. Brown

We present a deep generative model for learning to predict classes not seen at training time. Unlike most existing methods for this problem, that represent each class as a point (via a semantic embedding), we represent each seen/unseen…

Machine Learning · Computer Science 2017-11-21 Wenlin Wang , Yunchen Pu , Vinay Kumar Verma , Kai Fan , Yizhe Zhang , Changyou Chen , Piyush Rai , Lawrence Carin

Recent advances in neural-based generative modeling have reignited the hopes of having computer systems capable of conversing with humans and able to understand natural language. The employment of deep neural architectures has been largely…

Computation and Language · Computer Science 2022-11-16 Haoqin Tu , Yitong Li
‹ Prev 1 8 9 10 Next ›