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The hydroxyl-terminated self-assembled monolayer (OH-SAM), as a surface resistant to protein adsorption, exhibits substantial potential in applications such as ship navigation and medical implants, and the appropriate strategies for…

Biological Physics · Physics 2024-01-05 Dangxin Mao , Yuan-Yan Wu , Yusong Tu

Current major approaches to access surface hydrophobicity include directly introducing hydrophobic nonpolar groups/molecules into surface or elaborately fabricating surface roughness. Here, for the first time, molecular dynamics simulations…

Applied Physics · Physics 2021-02-08 Dangxin Mao , Xian Wang , Yuanyan Wu , Zonglin Gu , Chunlei Wang , Yusong Tu

The adsorption of a collagen fragment on both a hydrophobic, hydrogen-terminated and a hydrophilic, natively oxidised Si surface is investigated using all-atom molecular dynamics. While favourable direct protein-surface interactions via…

Soft Condensed Matter · Physics 2019-03-27 Daniel J. Cole , Mike C. Payne , Lucio Colombi Ciacchi

Recent surveys have shown that the number of nanoparticle-based formulations actually used at the clinical level is significantly lower than expected a decade ago. One reason for this is that the nanoparticle physicochemical properties fall…

Self-limiting assembly of particles represents the state-of-the-art controllability in nanomanufacturing processes where the assembly stops at a designated stage1,2, providing a desirable platform for applications requiring delicate…

Atomic and Molecular Clusters · Physics 2021-11-02 Liang Zhao , Bchara Sidnawi , Jichao Fan , Ruiyang Chen , Thomas Scully , Scott Dietrich , Weilu Gao , Qianhong Wu , Bo Li

Self-assembled monolayers (SAMs) have been used to improve both the positive and negative bias-stress stability of amorphous indium gallium zinc oxide (IGZO) bottom gate thin film transistors (TFTs). N-hexylphosphonic acid (HPA) and…

Molecular adhesion promoters are a central component of modern coating systems for the corrosion protection of structural materials. They are interface active and form ultrathin corrosion inhibiting and adhesion-promoting layers. Here we…

Materials Science · Physics 2022-01-05 Dominik Dworschak , Carina Brunnhofer , Markus Valtiner

Environmental oxidation has a great impact in tuning the physical, chemical and electronic properties of two-dimensional (2D) monolayers which can affect their practical applications in nanoscale engineering devices under ambient…

Materials Science · Physics 2025-11-18 Soumendra Kumar Das , Prasanjit Samal , Brahmananda Chakraborty , Sridhar Sahu

Orientation and three-dimensional structure of immobilized proteins on bio-devices are very important to assure their high performance. Time-of-flight secondary ion mass spectrometry (TOF-SIMS) is able to analyze upper surface of one layer…

Biological Physics · Physics 2010-01-18 Satoka Aoyagi , Alain Rouleau , Wilfrid Boireau

Molecular self-assembly has been extensively used for surface modification of metals and oxides for a variety of applications, including molecular and organic electronics. One of the goals of this research is to learn how the electronic…

Materials Science · Physics 2009-11-13 M. F. Calhoun , J. Sanchez , D. Olaya , M. E. Gershenson , V. Podzorov*

The adsorption of lysozyme, cytochrome c and myoglobin, similar-sized globular proteins of approximately 1.5 nm radius, into the mesoporous silica material Santa Barbara Amorphous-15 (SBA-15) with 3.3 nm mean pore radius has been studied…

Soft Condensed Matter · Physics 2015-12-15 Sebastian T. Moerz , Patrick Huber

Enzyme-Linked ImmunoSorbent Assays (ELISA) are a range of widely used analytical methods whose implementation requires to build antibodies (IgG) thin films onto surfaces predominantly made of polystyrene. The high hydrophobicity of…

Chemical Physics · Physics 2016-02-24 P. de Thier

The behavior of proteins near interfaces is relevant for biological and medical purposes. Previous results in bulk show that, when the protein concentration increases, the proteins unfold and, at higher concentrations, aggregate. Here, we…

Soft Condensed Matter · Physics 2021-01-19 David March , Valentino Bianco , Giancarlo Franzese

Ab initio total energy calculations within the framework of density functional theory have been performed for atomic hydrogen and oxygen chemisorption on the (0001) surface of double hexagonal packed americium using a full-potential…

Strongly Correlated Electrons · Physics 2015-05-14 P. P. Dholabhai , R. Atta-Fynn , A. K. Ray

Statistical analysis of protein-protein interactions shows anomalously high frequency of homodimers [Ispolatov, I., et al. (2005) Nucleic Acids Res 33, 3629-35]. Furthermore, recent findings [Wright, C.F., et al. (2005) Nature 438, 878-81]…

Biomolecules · Quantitative Biology 2007-05-23 D. B. Lyjatsky , E. I. Shakhnovich

Group IV and V monolayers are the promising state-of-the-art 2D materials owing to their high carrier mobility, tunable bandgaps, and optical linear dichroism along with outstanding electronic and thermoelectric properties. Furthermore,…

Computational Physics · Physics 2021-07-07 X. Q. Shu , J. H. Lin , H. Zhang

Protein-protein binding enables orderly and lawful biological self-organization, and is therefore considered a miracle of nature. Protein-protein binding is steered by electrostatic forces, hydrogen bonding, van der Waals force, and…

Biomolecules · Quantitative Biology 2022-02-23 Lin Yang , Shuai Guo , Chengyu Hou , Chencheng Liao , Jiacheng Li , Liping Shi , Xiaoliang Ma , Shenda Jiang , Bing Zheng , Yi Fang , Lin Ye , Xiaodong He

Alkylsilane self-assembled monolayers (SAMs) are often used as model substrates for their ease of preparation and hydrophobic properties. We have observed that these atomically smooth monolayers also provide a slip boundary condition for…

Unstructured proteins can modulate cellular responses to environmental conditions by undergoing coil-globule transitions and phase separation. However, the molecular mechanisms of these phenomena still need to be fully understood. Here, we…

Soft Condensed Matter · Physics 2023-06-28 Bernat Durà Faulí , Valentino Bianco , Giancarlo Franzese

Nanoparticles with hydrophobic capping ligands and amphiphilic phospholipids are both found to self-assemble into monolayer films when deposited on the air water interface. By separately measuring the anisotropic stress response of these…

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