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Image-to-image translation is a vital component in medical imaging processing, with many uses in a wide range of imaging modalities and clinical scenarios. Previous methods include Generative Adversarial Networks (GANs) and Diffusion Models…

Image and Video Processing · Electrical Eng. & Systems 2024-08-15 Yinchi Zhou , Tianqi Chen , Jun Hou , Huidong Xie , Nicha C. Dvornek , S. Kevin Zhou , David L. Wilson , James S. Duncan , Chi Liu , Bo Zhou

Dose reduction in computed tomography (CT) is essential for decreasing radiation risk in clinical applications. Iterative reconstruction is one of the most promising ways to compensate for the increased noise due to reduction of photon…

Image and Video Processing · Electrical Eng. & Systems 2021-03-24 Zhuonan He , Yikun Zhang , Yu Guan , Shanzhou Niu , Yi Zhang , Yang Chen , Qiegen Liu

Recent works demonstrate the effectiveness of diffusion models as unsupervised solvers for inverse imaging problems. Sparse-view computed tomography (CT) has greatly benefited from these advancements, achieving improved generalization…

Image and Video Processing · Electrical Eng. & Systems 2025-05-28 Ezgi Demircan-Tureyen , Felix Lucka , Tristan van Leeuwen

Low-dose computed tomography (CT) allows the reduction of radiation risk in clinical applications at the expense of image quality, which deteriorates the diagnosis accuracy of radiologists. In this work, we present a High-Quality Imaging…

Image and Video Processing · Electrical Eng. & Systems 2021-04-02 Jingfeng Lu , Shuo Wang , Ping Li , Dong Ye

Score-based diffusion models have significantly advanced generative deep learning for image processing. Measurement conditioned models have also been applied to inverse problems such as CT reconstruction. However, the conventional approach,…

Medical Physics · Physics 2025-02-24 Matthew Tivnan , Dufan Wu , Quanzheng Li

Objective: Cone-beam computed tomography (CBCT) provides a low-dose imaging alternative to conventional CT, but suffers from noise, scatter, and artifacts that degrade image quality. Synthetic CT (sCT) aims to translate CBCT to high-quality…

Medical Physics · Physics 2025-09-23 Alzahra Altalib , Chunhui Li , Alessandro Perelli

Recently, the diffusion model has emerged as a superior generative model that can produce high quality and realistic images. However, for medical image translation, the existing diffusion models are deficient in accurately retaining…

Image and Video Processing · Electrical Eng. & Systems 2023-10-31 Yunxiang Li , Hua-Chieh Shao , Xiao Liang , Liyuan Chen , Ruiqi Li , Steve Jiang , Jing Wang , You Zhang

X-ray Computed Tomography (CT) is an important tool in medical imaging to obtain a direct visualization of patient anatomy. However, the x-ray radiation exposure leads to the concern of lifetime cancer risk. Low-dose CT scan can reduce the…

Medical Physics · Physics 2018-10-30 Guoyang Ma , Chenyang Shen , Xun Jia

Computed Tomography (CT) technology reduces radiation haz-ards to the human body through sparse sampling, but fewer sampling angles pose challenges for image reconstruction. Score-based generative models are widely used in sparse-view CT…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Junyan Zhang , Mengxiao Geng , Pinhuang Tan , Yi Liu , Zhili Liu , Bin Huang , Qiegen Liu

In the intention of minimizing excessive X-ray radiation administration to patients, low-dose computed tomography (LDCT) has become a distinct trend in radiology. However, while lowering the radiation dose reduces the risk to the patient,…

Medical Physics · Physics 2022-04-12 Long Zhou , Xiaozhuang Wang , Min Hou , Ping Li , Chunlong Fu , Yanjun Ren , Tingting Shao , Xi Hu , Jihong Sun , Hongwei Ye

Limited Angle Computed Tomography (LACT) often faces significant challenges due to missing angular information. Unlike previous methods that operate in the image domain, we propose a new method that focuses on sinogram inpainting. We…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Jiaqi Guo , Santiago Lopez-Tapia , Aggelos K. Katsaggelos

Diffusion models have demonstrated significant potential in producing high-quality images in medical image translation to aid disease diagnosis, localization, and treatment. Nevertheless, current diffusion models have limited success in…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Yunxiang Li , Hua-Chieh Shao , Xiaoxue Qian , You Zhang

Diffusion model shows remarkable potential on sparse-view computed tomography (SVCT) reconstruction. However, when a network is trained on a limited sample space, its generalization capability may be constrained, which degrades performance…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Zekun Zhou , Tan Liu , Bing Yu , Yanru Gong , Liu Shi , Qiegen Liu

Reducing the radiation dose in computed tomography (CT) is important to mitigate radiation-induced risks. One option is to employ a well-trained model to compensate for incomplete information and map sparse-view measurements to the CT…

Image and Video Processing · Electrical Eng. & Systems 2023-03-29 Xiaoyue Li , Kai Shang , Gaoang Wang , Mark D. Butala

Low-dose computed tomography (LDCT) reduces radiation exposure but suffers from image artifacts and loss of detail due to quantum and electronic noise, potentially impacting diagnostic accuracy. Transformer combined with diffusion models…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Qiqing Liu , Guoquan Wei , Zekun Zhou , Yiyang Wen , Liu Shi , Qiegen Liu

Latest diffusion-based methods for many image restoration tasks outperform traditional models, but they encounter the long-time inference problem. To tackle it, this paper proposes a Wavelet-Based Diffusion Model (WaveDM). WaveDM learns the…

Computer Vision and Pattern Recognition · Computer Science 2024-01-26 Yi Huang , Jiancheng Huang , Jianzhuang Liu , Mingfu Yan , Yu Dong , Jiaxi Lv , Chaoqi Chen , Shifeng Chen

Ultra-low-dose positron emission tomography (PET) reconstruction holds significant potential for reducing patient radiation exposure and shortening examination times. However, it may also lead to increased noise and reduced imaging detail,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Mengxiao Geng , Ran Hong , Bingxuan Li , Qiegen Liu

Low-Dose computer tomography (LDCT) is an ideal alternative to reduce radiation risk in clinical applications. Although supervised-deep-learning-based reconstruction methods have demonstrated superior performance compared to conventional…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Feng Wang , Renfang Wang , Hong Qiu

Computed tomography (CT) serves as an effective tool for lung cancer screening, diagnosis, treatment, and prognosis, providing a rich source of features to quantify temporal and spatial tumor changes. Nonetheless, the diversity of CT…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 Md Selim , Jie Zhang , Faraneh Fathi , Michael A. Brooks , Ge Wang , Guoqiang Yu , Jin Chen

Cone-beam computed tomography (CBCT) is widely used in image-guided radiotherapy. Reconstructing CBCTs from limited-angle acquisitions (LA-CBCT) is highly desired for improved imaging efficiency, dose reduction, and better mechanical…

Medical Physics · Physics 2024-04-10 Jiacheng Xie , Hua-Chieh Shao , Yunxiang Li , You Zhang