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The transport of polymers with folded configurations across membrane pores is investigated theoretically by analyzing simple discrete stochastic models. The translocation dynamics is viewed as a sequence of two events: motion of the folded…

Statistical Mechanics · Physics 2009-11-13 Stanislav Kotsev , Anatoly B. Kolomeisky

We analyze the dynamics of an active tracer particle embedded in a thermal lattice gas. All particles are subject to exclusion up to third nearest neighbors on the square lattice, which leads to slow dynamics at high densities. For the case…

Soft Condensed Matter · Physics 2019-04-15 Rakesh Chatterjee , Nimrod Segall , Carl Merrigan , Kabir Ramola , Bulbul Chakraborty , Yair Shokef

Artificially synthesized Janus particles have tremendous prospective as in-vivo drug-delivery agents due to the possibility of self-propulsion by external stimuli. Here we report the first ever computational study of translational and…

Soft Condensed Matter · Physics 2017-04-21 Nairhita Samanta , Rohit Goswami , Rajarshi Chakrabarti

We analyze the dynamics of a tracer particle embedded in a bath of hard spheres confined in a channel of varying section. By means of Brownian dynamics simulations we apply a constant force on the tracer particle and discuss the dependence…

Soft Condensed Matter · Physics 2018-11-14 Antonio M. Puertas , Paolo Malgaretti , Ignacio Pagonabarraga

Using molecular dynamics simulations we study the static and dynamic properties of spherical nanoparticles (NPs) embedded in a disordered and polydisperse polymer network. Purely repulsive (RNP) as well as weakly attractive (ANP) polymer-NP…

Soft Condensed Matter · Physics 2023-02-15 Valerio Sorichetti , Virginie Hugouvieux , Walter Kob

Many fascinating properties of biological active matter crucially depend on the capacity of constituting entities to perform directed motion, e.g., molecular motors transporting vesicles inside cells or bacteria searching for food. While…

Statistical Mechanics · Physics 2023-06-21 Pietro Luigi Muzzeddu , Édgar Roldán , Andrea Gambassi , Abhinav Sharma

Semi-flexible polymers in crowded environments exhibit complex dynamics that play a crucial role in various biological and material design processes. Based on the classic reptation theory, it is generally believed that semiflexible polymers…

Soft Condensed Matter · Physics 2023-05-05 Ahmad Reza Motezakker , Andrés Córdoba , Tomas Rosén , Fredrik Lundell , L. Daniel Söderberg

We study a two-dimensional diffusive motion of a tracer particle in restricted, crowded anisotropic geometries. The underlying medium is the same as in our previous work [J. Chem. Phys. 140, 044706 (2014)] in which standard, gaussian…

Chemical Physics · Physics 2020-03-17 Michał Cieśla , Bartłomiej Dybiec , Ewa Gudowska-Nowak , Igor Sokolov

We present a theoretical description of the dynamics of a semi-flexible polymer being pulled through a nanopore by an external force acting at the pore. Our theory is based on the tensile blob picture of Pincus in which the front of the…

Statistical Mechanics · Physics 2015-09-16 Pui-Man Lam , Yi Zhen

Experiments have shown that self-propelled particles can slide along the surface of a circular obstacle without becoming trapped over long times. Using simulations and theory, we study the impact of boundary conditions on the diffusive…

Biological Physics · Physics 2019-01-30 Theresa Jakuszeit , Ottavio A. Croze , Samuel Bell

We investigate the obstructed motion of tracer (test) particles in crowded environments by carrying simulations of two-dimensional Gaussian random walk in model fibrinogen monolayers of different orientational ordering. The fibrinogen…

Chemical Physics · Physics 2014-03-14 Michał Cieśla , Ewa Gudowska-Nowak , Francesc Sagués , Igor M. Sokolov

The paper addresses the single-file diffusion in the presence of an absorbing boundary. The emphasis is on an interplay between the hard-core interparticle interaction and the absorption process. The resulting dynamics exhibits several…

Statistical Mechanics · Physics 2014-02-26 Artem Ryabov , Petr Chvosta

The dynamics and the steady states of a point-like tracer particle immersed in a confined critical fluid are studied. The fluid is modeled field-theoretically in terms of an order parameter (concentration or density field) obeying…

Statistical Mechanics · Physics 2023-01-03 Markus Gross

We explore the dynamics of a tracer in an active particle harmonic chain, investigating the influence of interactions. Our analysis involves calculating mean-squared displacements (MSD) and space-time correlations through Green's function…

Statistical Mechanics · Physics 2026-04-07 Subhajit Paul , Abhishek Dhar , Debasish Chaudhuri

The translocation of biopolymers, such as DNA and proteins, across cellular or nuclear membranes is essential for numerous biological processes. The translocation dynamics are influenced by the properties of the polymers, such as polymer…

Soft Condensed Matter · Physics 2024-07-29 Gokul Upadhyay , Rajeev Kapri , Anil Kumar Dasanna , Abhishek Chaudhuri

We study the diffusion process through an ideal polymer network, using numerical methods. Polymers are modeled by random walks on the bonds of a two-dimensional square lattice. Molecules occupy the lattice cells and may jump to the…

Statistical Mechanics · Physics 2007-05-23 Yong Wu , B Schmittmann , R K P Zia

We study the dynamics of polymer chains in a bath of self-propelled particles (SPP) by extensive Langevin dynamics simulations in a two dimensional system. Specifically, we analyse the polymer looping properties versus the SPP activity and…

Soft Condensed Matter · Physics 2016-09-26 J. Shin , A. G. Cherstvy , W. K. Kim , R. Metzler

Transport of rodlike particles in confinement environments of macromolecular networks plays crucial roles in many important biological processes and technological applications. The relevant understanding has been limited to thin rods with…

By embedding inert tracer particles (TPs) in a growing multicellular spheroid the local stresses on the cancer cells (CCs) can be measured. In order for this technique to be effective the unknown effect of the dynamics of the TPs on the CCs…

Biological Physics · Physics 2020-10-20 Himadri S. Samanta , Sumit Sinha , D. Thirumalai

We study analytically the dynamics and the micro-structural changes of a host medium caused by a driven tracer particle moving in a confined, quiescent molecular crowding environment. Imitating typical settings of active micro-rheology…

Statistical Mechanics · Physics 2016-03-17 O. Bénichou , P. Illien , G. Oshanin , A. Sarracino , R. Voituriez