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A combinatorial optimization problem is to find an optimal solution under the constraints. This is one of the potential applications for quantum computers. Quantum Random Access Optimization (QRAO) is the quantum optimization algorithm that…

Quantum Physics · Physics 2024-05-03 Hiromichi Matsuyama , Wei-hao Huang , Kohji Nishimura , Yu Yamashiro

Background: Beam angle optimization (BAO) is a critical component of radiation therapy (RT) treatment planning, where small changes in beam configuration can significantly impact treatment quality, especially for proton RT. Mathematically,…

Medical Physics · Physics 2025-09-08 Nimita Shinde , Ya-Nan Zhu , Haozheng Shen , Hao Gao

A novel class of hybrid quantum-classical algorithms based on the variational approach have recently emerged from separate proposals addressing, for example, quantum chemistry and combinatorial problems. These algorithms provide an…

Quantum Physics · Physics 2017-01-09 Gian Giacomo Guerreschi , Mikhail Smelyanskiy

The LogQ algorithm encodes Quadratic Unconstrained Binary Optimization (QUBO) problems with exponentially fewer qubits than the Quantum Approximate Optimization Algorithm (QAOA). The advantages of conventional LogQ are accompanied by a…

Quantum Physics · Physics 2025-07-14 Yagnik Chatterjee , Jérémie Messud

The Quantum Approximate Optimization Algorithm (QAOA) is an algorithmic framework for finding approximate solutions to combinatorial optimization problems, derived from an approximation to the Quantum Adiabatic Algorithm (QAA). In solving…

Quantum Physics · Physics 2020-02-05 Yue Ruan , Samuel Marsh , Xilin Xue , Xi Li , Zhihao Liu , Jingbo Wang

In this paper, we propose a hybrid framework to solve large-scale permutation-based combinatorial problems effectively using a high-performance quadratic unconstrained binary optimization (QUBO) solver. To do so, transformations are…

Optimization and Control · Mathematics 2021-07-07 Siong Thye Goh , Sabrish Gopalakrishnan , Jianyuan Bo , Hoong Chuin Lau

The Vehicle Routing Problem (VRP) is a fundamental combinatorial optimization challenge with broad applications in logistics and transportation. In this work, we present a quantum-assisted framework that integrates the Quantum Approximate…

Quantum Physics · Physics 2026-01-28 Talha Azfar , Osama Muhammad Raisuddin , Ruimin Ke , Jose Holguin-Veras

There is an increasing interest in quantum algorithms for problems of integer programming and combinatorial optimization. Classical solvers for such problems employ relaxations, which replace binary variables with continuous ones, for…

Quantum Physics · Physics 2021-06-23 Daniel J. Egger , Jakub Marecek , Stefan Woerner

Recent advances in quantum computing and the increasing availability of quantum hardware have substantially enhanced the practical relevance of quantum approaches to discrete optimization. Among these, the Quadratic Unconstrained Binary…

Quantum Physics · Physics 2026-02-12 Felix P. Broesamle , Stefan Nickel

We propose a technique for optimizing parameterized circuits in variational quantum algorithms based on the probabilistic tensor sampling optimization. This method allows one to relax random initialization issues or heuristics for…

Quantum Physics · Physics 2024-02-01 G. V. Paradezhenko , A. A. Pervishko , D. Yudin

The Quadratic Unconstrained Binary Optimization (QUBO) model has gained prominence in recent years with the discovery that it unifies a rich variety of combinatorial optimization problems. By its association with the Ising problem in…

Data Structures and Algorithms · Computer Science 2019-11-06 Fred Glover , Gary Kochenberger , Yu Du

Routing in wireless communication networks is shaped by mobility, interference, congestion, and competing service requirements, making route selection a high-dimensional constrained optimization problem rather than a simple shortest-path…

This paper proposes a quantum approximate optimization algorithm (QAOA) method for wireless scheduling problems. The QAOA is one of the promising hybrid quantum-classical algorithms for many applications and it provides highly accurate…

Other Computer Science · Computer Science 2020-09-07 Jaeho Choi , Seunghyeok Oh , Joongheon Kim

As quantum computing advances, quantum approximate optimization algorithms (QAOA) have shown promise in addressing combinatorial optimization problems. However, the limitations of Noisy Intermediate Scale Quantum (NISQ) devices hinder the…

The variational quantum power method (VQPM), which adapts the classical power iteration algorithm for quantum settings, has shown promise for eigenvector estimation and optimization on quantum hardware. In this work, we provide a…

Quantum Physics · Physics 2026-01-26 Ammar Daskin

Quantum optimization has emerged as a promising frontier of quantum computing, providing novel numerical approaches to mathematical optimization problems. The main goal of this paper is to facilitate interdisciplinary research between the…

Optimization and Control · Mathematics 2025-09-05 Alexey Bochkarev , Raoul Heese , Sven Jäger , Philine Schiewe , Anita Schöbel

The prospect of quantum solutions for complicated optimization problems is contingent on mapping the original problem onto a tractable quantum energy landscape, e.g. an Ising-type Hamiltonian. Subsequently, techniques like adiabatic…

Quantum Physics · Physics 2025-10-17 Sebastian Egginger , Kristina Kirova , Sonja Bruckner , Stefan Hillmich , Richard Kueng

The Quantum Approximate Optimization Algorithm (QAOA) constitutes one of the often mentioned candidates expected to yield a quantum boost in the era of near-term quantum computing. In practice, quantum optimization will have to compete with…

Quantum Physics · Physics 2020-10-15 Charles Moussa , Henri Calandra , Vedran Dunjko

The quantum approximate optimization algorithm (QAOA) is a variational quantum algorithm (VQA) ideal for noisy intermediate-scale quantum (NISQ) processors, and is highly successful in solving combinatorial optimization problems (COPs). It…

Quantum Physics · Physics 2026-03-23 Francesco Aldo Venturelli , Sreetama Das , Filippo Caruso

Constrained optimization problems are ubiquitous in science and industry. Quantum algorithms have shown promise in solving optimization problems, yet none of the current algorithms can effectively handle arbitrary constraints. We introduce…

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