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We introduce DT-ICU, a multimodal digital twin framework for continuous risk estimation in intensive care. DT-ICU integrates variable-length clinical time series with static patient information in a unified multitask architecture, enabling…

Machine Learning · Computer Science 2026-01-13 Wen Guo

Medical multimodal representation learning aims to integrate heterogeneous data into unified patient representations to support clinical outcome prediction. However, real-world medical datasets commonly contain systematic biases from…

Machine Learning · Computer Science 2026-05-19 Xiaoguang Zhu , Linxiao Gong , Lianlong Sun , Yang Liu , Haoyu Wang , Jing Liu

Given the rising complexity and burden of multimorbidity, it is crucial to provide evidence-based support for managing multimorbidity-related clinical outcomes. This study introduces a dynamic network approach to investigate conditional and…

Methodology · Statistics 2025-04-10 Hao Mei , Haonan Xiao , Ben-Chang Shia , Guanzhong Qiao , Yang Li

To empower users of wearable medical devices, it is important to enable methods that facilitate reflection on previous care to improve future outcomes. In this work, we conducted a two-phase user-study involving patients, caregivers, and…

Computers and Society · Computer Science 2020-07-28 Temiloluwa Prioleau , Ashutosh Sabharwal , Madhuri M. Vasudevan

Transformers have demonstrated remarkable performance in natural language processing and computer vision. However, existing vision Transformers struggle to learn from limited medical data and are unable to generalize on diverse medical…

Image and Video Processing · Electrical Eng. & Systems 2023-04-06 Yunhe Gao , Mu Zhou , Di Liu , Zhennan Yan , Shaoting Zhang , Dimitris N. Metaxas

Medical image interpretation is central to most clinical applications such as disease diagnosis, treatment planning, and prognostication. In clinical practice, radiologists examine medical images and manually compile their findings into…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Nurbanu Aksoy , Nishant Ravikumar , Alejandro F Frangi

Multimodal deep learning has been used to predict clinical endpoints and diagnoses from clinical routine data. However, these models suffer from scaling issues: they have to learn pairwise interactions between each piece of information in…

Large-scale population-based studies in medicine are a key resource towards better diagnosis, monitoring, and treatment of diseases. They also serve as enablers of clinical decision support systems, in particular Computer Aided Diagnosis…

Machine Learning · Computer Science 2022-03-01 Gerome Vivar , Anees Kazi , Hendrik Burwinkel , Andreas Zwergal , Nassir Navab , Seyed-Ahmad Ahmadi

The collection of large, complex datasets has become common across a wide variety of domains. Visual analytics tools increasingly play a key role in exploring and answering complex questions about these large datasets. However, many…

Human-Computer Interaction · Computer Science 2020-06-19 David Borland , Wenyuan Wang , Jonathan Zhang , Joshua Shrestha , David Gotz

Visual analytics systems enable highly interactive exploratory data analysis. Across a range of fields, these technologies have been successfully employed to help users learn from complex data. However, these same exploratory visualization…

Human-Computer Interaction · Computer Science 2021-01-25 Zhilan Zhou , Ximing Wen , Yue Wang , David Gotz

Multi-modal medical imaging enables comprehensive diagnostics, yet current foundation models process 2D (e.g. X-ray) and 3D (e.g. CT) data with separate, dimensionality-specific architectures. We present MultiMedVision, a unified framework…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Frank Li , Bardia Khosravi , Mohammadreza Chavoshi , Young Seok Jeon , Theo Dapamede , Hari Trivedi , Janice Newsome , Judy Gichoya

Deep neural networks are often applied to medical images to automate the problem of medical diagnosis. However, a more clinically relevant question that practitioners usually face is how to predict the future trajectory of a disease.…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Huy Hoang Nguyen , Matthew B. Blaschko , Simo Saarakkala , Aleksei Tiulpin

The combination of clinical and personal health and wellbeing data can tell us much about our behaviors, risks and overall status. The way this data is visualized may affect our understanding of our own health. To study this effect, we…

Human-Computer Interaction · Computer Science 2016-04-08 Andres Ledesma , Hannu Nieminen , Päivi Valve , Miikka Ermes , Holly Jimison , Misha Pavel

Intensive Care Units (ICU) require comprehensive patient data integration for enhanced clinical outcome predictions, crucial for assessing patient conditions. Recent deep learning advances have utilized patient time series data, and fusion…

Machine Learning · Computer Science 2023-11-14 Samyak Jain , Manuel Burger , Gunnar Rätsch , Rita Kuznetsova

With the wide application of electronic health records (EHR) in healthcare facilities, health event prediction with deep learning has gained more and more attention. A common feature of EHR data used for deep-learning-based predictions is…

Machine Learning · Computer Science 2021-12-17 Chang Lu , Tian Han , Yue Ning

The vast amount of health data has been continuously collected for each patient, providing opportunities to support diverse healthcare predictive tasks such as seizure detection and hospitalization prediction. Existing models are mostly…

Machine Learning · Computer Science 2023-02-16 Chaoqi Yang , M. Brandon Westover , Jimeng Sun

Multiple adverse health conditions co-occurring in a patient are typically associated with poor prognosis and increased office or hospital visits. Developing methods to identify patterns of co-occurring conditions can assist in diagnosis.…

Computation and Language · Computer Science 2017-11-30 Moumita Bhattacharya , Claudine Jurkovitz , Hagit Shatkay

Many applications collect a large number of time series, for example, the financial data of companies quoted in a stock exchange, the health care data of all patients that visit the emergency room of a hospital, or the temperature sequences…

Information Theory · Computer Science 2017-02-09 Jonathan Mei , José M. F. Moura

Deep learning models have achieved strong performance in medical image analysis, but their internal decision processes remain difficult to interpret. Concept Bottleneck Models (CBMs) partially address this limitation by structuring…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Getamesay Dagnaw , Xuefei Yin , Muhammad Hassan Maqsood , Yanming Zhu , Alan Wee-Chung Liew

Personalized predictive medicine necessitates the modeling of patient illness and care processes, which inherently have long-term temporal dependencies. Healthcare observations, recorded in electronic medical records, are episodic and…

Machine Learning · Statistics 2017-04-12 Trang Pham , Truyen Tran , Dinh Phung , Svetha Venkatesh