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Dynamical balance of excitation and inhibition is usually invoked to explain the irregular low firing activity observed in the cortex. We propose a robust nonlinear balancing mechanism for a random network of spiking neurons, which works…

Disordered Systems and Neural Networks · Physics 2025-05-29 Antonio Politi , Alessandro Torcini

The living cell expends energetic and material resources to reliably process information from its environment. To do so, it utilises unreliable molecular circuitry that is subject to thermal and other fluctuations. Here, we argue that…

Soft Condensed Matter · Physics 2022-04-12 Kabir Husain , Sriram Ramaswamy , Madan Rao

In this work we study biological neural networks from an algorithmic perspective, focusing on understanding tradeoffs between computation time and network complexity. Our goal is to abstract real neural networks in a way that, while not…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-04-30 Nancy Lynch , Cameron Musco , Merav Parter

Spiking Neural Networks (SNN) are mathematical models in neuroscience to describe the dynamics among a set of neurons that interact with each other by firing instantaneous signals, a.k.a., spikes. Interestingly, a recent advance in…

Neural and Evolutionary Computing · Computer Science 2018-11-22 Chi-Ning Chou , Kai-Min Chung , Chi-Jen Lu

Understanding active matter has led to new perspectives on biophysics and non-equilibrium dynamics. However, the development of numerical tools for simulating active fluids capable of incorporating non-trivial boundaries or inclusions has…

Soft Condensed Matter · Physics 2024-02-01 Timofey Kozhukhov , Benjamin Loewe , Tyler N. Shendruk

A novel approach to moment closure problem is used to derive low dimensional laws for the dynamics of the moments of the membrane potential distribution in a population of spiking neurons. Using spectral expansion of the density equation we…

Statistical Mechanics · Physics 2025-07-08 Gianni Valerio Vinci , Roberto Benzi , Maurizio Mattia

Calcium imaging permits optical measurement of neural activity. Since intracellular calcium concentration is an indirect measurement of neural activity, computational tools are necessary to infer the true underlying spiking activity from…

Machine Learning · Statistics 2017-11-07 Artur Speiser , Jinyao Yan , Evan Archer , Lars Buesing , Srinivas C. Turaga , Jakob H. Macke

This paper introduces a class of stochastic models of interacting neurons with emergent dynamics similar to those seen in local cortical populations, and compares them to very simple reduced models driven by the same mean excitatory and…

Neurons and Cognition · Quantitative Biology 2017-11-07 Yao Li , Logan Chariker , Lai-Sang Young

Building robust, interpretable, and secure AI system requires quantifying and representing uncertainty under a probabilistic perspective to mimic human cognitive abilities. However, probabilistic computation presents significant challenges…

Machine Learning · Computer Science 2024-01-15 Hengyuan Ma , Yang Qi , Li Zhang , Wenlian Lu , Jianfeng Feng

Neurons in sensory systems encode stimulus information into their stochastic spiking response. The mutual information has been extensively applied to these systems to quantify the neurons' capacity of transmitting such information. Yet,…

Neurons and Cognition · Quantitative Biology 2025-09-09 Tobias Kühn , Gabriel Mahuas , Ulisse Ferrari

Markov automata (MA) constitute an expressive continuous-time compositional modelling formalism. They appear as semantic backbones for engineering frameworks including dynamic fault trees, Generalised Stochastic Petri Nets, and AADL. Their…

Logic in Computer Science · Computer Science 2013-05-31 Dennis Guck , Hassan Hatefi , Holger Hermanns , Joost-Pieter Katoen , Mark Timmer

Spiking neural networks (SNNs) promise low-power event-driven computation for temporally rich tasks, but commonly used neuron models often trade off gradient-based trainability, dynamical richness, and high activity sparsity. These…

Neural and Evolutionary Computing · Computer Science 2026-05-13 Alex Fulleda-Garcia , Saray Soldado-Magraner , Josep Maria Margarit-Taulé

CA has grown as potential classifier for addressing major problems in bioinformatics. Lot of bioinformatics problems like predicting the protein coding region, finding the promoter region, predicting the structure of protein and many other…

Computational Engineering, Finance, and Science · Computer Science 2014-01-13 Pokkuluri Kiran Sree , Inampudi Ramesh Babu , SSSN Usha Devi Nedunuri

Randomly connected networks of excitatory and inhibitory spiking neurons provide a parsimonious model of neural variability, but are notoriously unreliable for performing computations. We show that this difficulty is overcome by…

Neurons and Cognition · Quantitative Biology 2017-01-11 Ryan Pyle , Robert Rosenbaum

We provide an overview of Monte Carlo algorithms based on Markovian stochastic dynamics of interacting and reacting many-particle systems not in thermal equilibrium. These agent-based simulations are an effective way of introducing students…

Statistical Mechanics · Physics 2025-07-24 Mohamed Swailem , Ulrich Dobramysl , Ruslan Mukhamadiarov , Uwe C. Täuber

Spiking Neural Network (SNN) is considered more biologically realistic and power-efficient as it imitates the fundamental mechanism of the human brain. Recently, backpropagation (BP) based SNN learning algorithms that utilize deep learning…

Neural and Evolutionary Computing · Computer Science 2022-10-11 Chengting Yu , Yangkai Du , Mufeng Chen , Aili Wang , Gaoang Wang , Erping Li

The activation functions are fundamental to neural networks as they introduce non-linearity into data relationships, thereby enabling deep networks to approximate complex data relations. Existing efforts to enhance neural network…

Machine Learning · Computer Science 2024-09-26 Jiayu Li , Zilong Zhao , Kevin Yee , Uzair Javaid , Biplab Sikdar

With the rapid growth of neuroimaging technologies, a great effort has been dedicated recently to investigate the dynamic changes in brain activity. Examples include time course calcium imaging and dynamic brain functional connectivity. In…

Methodology · Statistics 2020-08-31 Wei Hu , Tianyu Pan , Dehan Kong , Weining Shen

Modern computer architectures support low-precision arithmetic, which present opportunities for the adoption of mixed-precision algorithms to achieve high computational throughput and reduce energy consumption. As a growing number of…

Computation · Statistics 2024-12-02 Sahil Bhola , Karthik Duraisamy

Many properties of perceptual decision making are well-modeled by deep neural networks. However, such architectures typically treat decisions as instantaneous readouts, overlooking the temporal dynamics of the decision process. We present…

Neurons and Cognition · Quantitative Biology 2025-11-25 Hayden R. Johnson , Anastasia N. Krouglova , Hadi Vafaii , Jacob L. Yates , Pedro J. Gonçalves
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