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Metal artefact reduction (MAR) techniques aim at removing metal-induced noise from clinical images. In Computed Tomography (CT), supervised deep learning approaches have been shown effective but limited in generalisability, as they mostly…
Quantitative measures of dopamine transporter (DaT) uptake in caudate, putamen, and globus pallidus derived from DaT-single-photon emission computed tomography (SPECT) images are being investigated as biomarkers to diagnose, assess disease…
X-ray Computed Tomography (CT) is an important tool in medical imaging to obtain a direct visualization of patient anatomy. However, the x-ray radiation exposure leads to the concern of lifetime cancer risk. Low-dose CT scan can reduce the…
Brain positron emission tomography (PET) imaging is broadly used in research and clinical routines to study, diagnose, and stage Alzheimer's disease (AD). However, its potential cannot be fully exploited yet due to the lack of portable…
Recently deep learning methods, in particular, convolutional neural networks (CNNs), have led to a massive breakthrough in the range of computer vision. Also, the large-scale annotated dataset is the essential key to a successful training…
Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic and radiotherapy (RT) planning tool, offering detailed insights into the anatomy of the human body. The extensive scan time is stressful for patients, who must remain motionless…
Convolutional Neural Networks (CNNs) work very well for supervised learning problems when the training dataset is representative of the variations expected to be encountered at test time. In medical image segmentation, this premise is…
Quantifying normative pediatric cranial development and suture ossification is crucial for diagnosing and treating growth-related cephalic disorders. Computed tomography (CT) is widely used to evaluate cranial and sutural deformities;…
Low-dose CT (LDCT) imaging is desirable in many clinical applications to reduce X-ray radiation dose to patients. Inspired by deep learning (DL), a recent promising direction of model-based iterative reconstruction (MBIR) methods for LDCT…
Historically, patient datasets have been used to develop and validate various reconstruction algorithms for PET/MRI and PET/CT. To enable such algorithm development, without the need for acquiring hundreds of patient exams, in this paper we…
Positron emission tomography (PET) is a critical tool for diagnosing tumors and neurological disorders but poses radiation risks to patients, particularly to sensitive populations. While reducing injected radiation dose mitigates this risk,…
Modeling and manufacturing of personalized cranial implants are important research areas that may decrease the waiting time for patients suffering from cranial damage. The modeling of personalized implants may be partially automated by the…
The deployment of pre-trained models (PTMs) has greatly advanced the field of continual learning (CL), enabling positive knowledge transfer and resilience to catastrophic forgetting. To sustain these advantages for sequentially arriving…
We aim to reduce the tedious nature of developing and evaluating methods for aligning PET-CT scans from multiple patient visits. Current methods for registration rely on correspondences that are created manually by medical experts with 3D…
Objective: To simultaneously deblur and supersample prostate specific membrane antigen (PSMA) positron emission tomography (PET) images using neural blind deconvolution. Approach: Blind deconvolution is a method of estimating the…
Intracranial aneurysms are a major cause of morbidity and mortality worldwide, and detecting them manually is a complex, time-consuming task. Albeit automated solutions are desirable, the limited availability of training data makes it…
Positron Emission Tomography (PET) is an important molecular imaging tool widely used in medicine. Traditional PET systems rely on complete detector rings for full angular coverage and reliable data collection. However, incomplete-ring PET…
A standard dose of radioactive tracer must be delivered into the patients body to obtain high-quality Positron Emission Tomography (PET) images for diagnostic purposes, which raises the risk of radiation harm. A reduced tracer dose, on the…
Due to numerous hardware shortcomings, medical image acquisition devices are susceptible to producing low-quality (i.e., low contrast, inappropriate brightness, noisy, etc.) images. Regrettably, perceptually degraded images directly impact…
Deep-neural-network-based image reconstruction has demonstrated promising performance in medical imaging for under-sampled and low-dose scenarios. However, it requires large amount of memory and extensive time for the training. It is…