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While randomized controlled trials (RCTs) are the gold standard for estimating treatment effects in medical research, there is increasing use of and interest in using real-world data for drug development. One such use case is the…

Methodology · Statistics 2021-10-11 Devin Incerti , Michael T Bretscher , Ray Lin , Chris Harbron

This work presents a comparative study of existing and new techniques to detect knee injuries by leveraging Stanford's MRNet Dataset. All approaches are based on deep learning and we explore the comparative performances of transfer learning…

Image and Video Processing · Electrical Eng. & Systems 2020-10-06 David Azcona , Kevin McGuinness , Alan F. Smeaton

Epidemics and pandemics have ravaged human life since time. To combat these, novel ideas have always been created and deployed by humanity, with varying degrees of success. At this very moment, the COVID-19 pandemic is the singular global…

The worldwide impact of the recent COVID-19 pandemic has been substantial, necessitating the development of accurate forecasting models to predict the spread and course of a pandemic. Previous methods for outbreak forecasting have faced…

Machine Learning · Computer Science 2024-08-28 Ashutosh Anshul , Jhalak Gupta , Mohammad Zia Ur Rehman , Nagendra Kumar

There is increasing interest in combining information from experimental studies, including randomized and single-group trials, with information from external experimental or observational data sources. Such efforts are usually motivated by…

Methodology · Statistics 2026-04-23 Lawson Ung , Guanbo Wang , Sebastien Haneuse , Miguel A. Hernán , Issa J. Dahabreh

The COVID-19 crisis has shown that we can only prevent the risk of mass contagion through timely, large-scale, coordinated, and decisive actions. However, frequently the models used by experts [from whom decision-makers get their main…

Applications · Statistics 2021-03-08 Mauricio Herrera

The global spread of COVID-19 had severe consequences for public health and the world economy. The quick onset of the pandemic highlighted the potential benefits of cheap and deployable pre-screening methods to monitor the prevalence of the…

Sound · Computer Science 2023-09-12 Andrej Jovanović , Mario Mihaly , Lennon Donaldson

The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has posed significant health challenges worldwide. While respiratory symptoms have been the primary focus, emerging evidence has highlighted the impact of COVID-19 on…

Machine Learning · Computer Science 2023-10-03 Maitham G. Yousif , Fadhil G. Al-Amran , Salman Rawaf , Mohammad Abdulla Grmt

A critical step in the fight against COVID-19, which continues to have a catastrophic impact on peoples lives, is the effective screening of patients presented in the clinics with severe COVID-19 symptoms. Chest radiography is one of the…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Tomasz Szczepański , Arkadiusz Sitek , Tomasz Trzciński , Szymon Płotka

Purpose: Accurate segmentation of lung and infection in COVID-19 CT scans plays an important role in the quantitative management of patients. Most of the existing studies are based on large and private annotated datasets that are…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Jun Ma , Yixin Wang , Xingle An , Cheng Ge , Ziqi Yu , Jianan Chen , Qiongjie Zhu , Guoqiang Dong , Jian He , Zhiqiang He , Yuntao Zhu , Ziwei Nie , Xiaoping Yang

Background: Acute kidney injury (AKI) is a clinical syndrome affecting almost one fifth of hospitalized patients, as well as more than half of the patients who are admitted to the intensive care unit (ICU). Stratifying AKI patients into…

COVID-19 is extremely contagious and its rapid growth has drawn attention towards its early diagnosis. Early diagnosis of COVID-19 enables healthcare professionals and government authorities to break the chain of transition and flatten the…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Sumera Rounaq , Shahid Munir Shah , Mahmoud Aljawarneh

The COVID-19 pandemic represents the most significant public health disaster since the 1918 influenza pandemic. During pandemics such as COVID-19, timely and reliable spatio-temporal forecasting of epidemic dynamics is crucial. Deep…

Machine Learning · Computer Science 2020-11-25 Lijing Wang , Aniruddha Adiga , Srinivasan Venkatramanan , Jiangzhuo Chen , Bryan Lewis , Madhav Marathe

The COVID-19 pandemic continues to have a devastating effect on the health and well-being of the global population. Apart from the global health crises, the pandemic has also caused significant economic and financial difficulties and…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Ashkan Ebadi , Pengcheng Xi , Alexander MacLean , Stéphane Tremblay , Sonny Kohli , Alexander Wong

COVID-19 clinical presentation and prognosis are highly variable, ranging from asymptomatic and paucisymptomatic cases to acute respiratory distress syndrome and multi-organ involvement. We developed a hybrid machine learning/deep learning…

Quantitative Methods · Quantitative Biology 2021-05-14 Matteo Chieregato , Fabio Frangiamore , Mauro Morassi , Claudia Baresi , Stefania Nici , Chiara Bassetti , Claudio Bnà , Marco Galelli

Longitudinal modified treatment policies (LMTP) have been recently developed as a novel method to define and estimate causal parameters that depend on the natural value of treatment. LMTPs represent an important advancement in causal…

Methodology · Statistics 2025-02-06 Iván Díaz , Katherine L Hoffman , Nima S. Hejazi

COVID-19 data released by public health authorities features the presence of notable time-delays, corresponding to the difference between actual time of infection and identification of infection. These delays have several causes, including…

Dynamical Systems · Mathematics 2021-11-29 Nicola Guglielmi , Elisa Iacomini , Alex Viguerie

The optimal moment to start renal replacement therapy in a patient with acute kidney injury (AKI) remains a challenging problem in intensive care nephrology. Multiple randomised controlled trials have tried to answer this question, but…

Applications · Statistics 2022-06-10 Pawel Morzywolek , Johan Steen , Wim Van Biesen , Johan Decruyenaere , Stijn Vansteelandt

The possibility to use widespread and simple chest X-ray (CXR) imaging for early screening of COVID-19 patients is attracting much interest from both the clinical and the AI community. In this study we provide insights and also raise…

Image and Video Processing · Electrical Eng. & Systems 2020-10-20 Enzo Tartaglione , Carlo Alberto Barbano , Claudio Berzovini , Marco Calandri , Marco Grangetto

Cardiovascular disease and chronic kidney disease are major complications of diabetes, leading to high morbidity and mortality. Early detection of these conditions is critical, yet traditional diagnostic markers often lack sensitivity in…

Other Quantitative Biology · Quantitative Biology 2025-10-20 Syed Ibad Hasnain