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Precision rehabilitation offers the promise of an evidence-based approach for optimizing individual rehabilitation to improve long-term functional outcomes. Emerging techniques, including those driven by artificial intelligence, are rapidly…

Quantitative Methods · Quantitative Biology 2024-11-07 R. James Cotton , Bryant A. Seamon , Richard L. Segal , Randal D. Davis , Amrita Sahu , Michelle M. McLeod , Pablo Celnik , Sharon L. Ramey

The accurate prediction of patient prognosis is a critical challenge in clinical practice. With the availability of various patient information, physicians can optimize medical care by closely monitoring disease progression and therapy…

Applications · Statistics 2023-11-28 He Weiyi

Context: Utilization of operating theaters is a major cost driver in hospitals. Optimizing this variable through optimized surgery schedules may significantly lower cost and simultaneously improve medical outcomes. Previous studies proposed…

Applications · Statistics 2025-09-05 Harald Störrle , Anastasia Hort

Stepped-wedge designs are increasingly used in randomized experiments to accommodate logistical and ethical constraints by staggering treatment roll-out over time. Despite their popularity, existing analytical methods largely rely on…

Methodology · Statistics 2026-02-12 Liangbo Lyu , Bingkai Wang

Surrogate models provide a quick-to-evaluate approximation to complex computational models and are essential for multi-query problems like design optimisation. The inputs of current deterministic computational models are usually…

Applications · Statistics 2024-10-15 Thomas A. Archbold , Ieva Kazlauskaite , Fehmi Cirak

One method to solve expensive black-box optimization problems is to use a surrogate model that approximates the objective based on previous observed evaluations. The surrogate, which is cheaper to evaluate, is optimized instead to find an…

Optimization and Control · Mathematics 2021-05-28 Rickard Karlsson , Laurens Bliek , Sicco Verwer , Mathijs de Weerdt

Many real-world processes are trajectories that may be regarded as continuous-time "functional data". Examples include patients' biomarker concentrations, environmental pollutant levels, and prices of stocks. Corresponding advances in data…

Statistics Theory · Mathematics 2022-11-30 Jinghao Sun , Forrest W. Crawford

Graphical modeling explores dependences among a collection of variables by inferring a graph that encodes pairwise conditional independences. For jointly Gaussian variables, this translates into detecting the support of the precision…

Methodology · Statistics 2018-02-16 Shota Katayama , Hironori Fujisawa , Mathias Drton

Centuries of development in natural sciences and mathematical modeling provide valuable domain expert knowledge that has yet to be explored for the development of machine learning models. When modeling complex physical systems, both domain…

Machine Learning · Computer Science 2020-09-01 Daniel L. Marino , Milos Manic

We study the causal effect with a functional treatment variable, where practical applications often arise in neuroscience, biomedical sciences, etc. Previous research concerning the effect of a functional variable on an outcome is typically…

Methodology · Statistics 2025-05-20 Ruoxu Tan , Wei Huang , Zheng Zhang , Guosheng Yin

A powerful tool for the analysis of nonrandomized observational studies has been the potential outcomes model. Utilization of this framework allows analysts to estimate average treatment effects. This article considers the situation in…

Statistics Theory · Mathematics 2019-05-31 Debashis Ghosh , Efrén Cruz-Cortés

The paper presents a method by which the mean field dynamics of a population of dynamical systems with parameter diversity and global coupling can be described in terms of a few macroscopic degrees of freedom. The method applies to…

Statistical Mechanics · Physics 2009-11-07 Silvia De Monte , Francesco d'Ovidio , Erik Mosekilde

This paper introduces sparse dynamic chain graph models for network inference in high dimensional non-Gaussian time series data. The proposed method parametrized by a precision matrix that encodes the intra time-slice conditional…

Methodology · Statistics 2018-05-28 Pariya Behrouzi , Fentaw Abegaz , Ernst C. Wit

Motivation: Quickly obtaining high-quality MRI from accelerated acquisitions is important to mitigate motion artifacts, maintain patient comfort, and improve clinical efficiency. Goals: To obtain high-quality dynamic MRI using efficient,…

Medical Physics · Physics 2026-03-24 M. L. Terpstra , C. A. T. van den Berg

Estimating optimal dynamic policies from offline data is a fundamental problem in dynamic decision making. In the context of causal inference, the problem is known as estimating the optimal dynamic treatment regime. Even though there exists…

Econometrics · Economics 2023-12-15 Qizhao Chen , Morgane Austern , Vasilis Syrgkanis

The paper proposes and investigates an approach for surrogate-assisted performance prediction of data-driven knowledge discovery algorithms. The approach is based on the identification of surrogate models for prediction of the target…

Machine Learning · Computer Science 2022-01-25 Anastasia A. Funkner , Aleksey N. Yakovlev , Sergey V. Kovalchuk

Estimating how much an intervention helps a given individual the conditional average treatment effect (CATE) is increasingly central to decision-making in medicine, economics, and policy, where an estimate is most useful when accompanied by…

Machine Learning · Statistics 2026-05-28 Eichi Uehara

The growing rate of chronic wound occurrence, especially in patients with diabetes, has become a concerning trend in recent years. Chronic wounds are difficult and costly to treat, and have become a serious burden on health care systems…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Bill Cassidy , Christian McBride , Connah Kendrick , Neil D. Reeves , Joseph M. Pappachan , Shaghayegh Raad , Moi Hoon Yap

Understanding treatment effects in extreme regimes is important for characterizing risks associated with different interventions. This is hindered by the unavailability of counterfactual outcomes and the rarity and difficulty of collecting…

Methodology · Statistics 2024-05-24 Ahmed Aloui , Ali Hasan , Yuting Ng , Miroslav Pajic , Vahid Tarokh

When it comes to clinical survival trials, regulatory restrictions usually require the application of methods that solely utilize baseline covariates and the intention-to-treat principle. Thereby a lot of potentially useful information is…