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The segmentation of optic disc(OD) and optic cup(OC) from fundus images is an important fundamental task for glaucoma diagnosis. In the clinical practice, it is often necessary to collect opinions from multiple experts to obtain the final…

Image and Video Processing · Electrical Eng. & Systems 2022-06-15 Junde Wu , Huihui Fang , Fangxin Shang , Zhaowei Wang , Dalu Yang , Wenshuo Zhou , Yehui Yang , Yanwu Xu

Objective: Accurate probability estimates are essential for the safe deployment of medical image segmentation models in clinical decision-making. However, modern deep segmentation networks are often poorly calibrated, a problem exacerbated…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Meritxell Riera-Marín , Javier García López , Júlia Rodríguez-Comas , Miguel A. González Ballester , Adrian Galdran

Deep learning-based object detectors have achieved impressive performance in microscopy imaging, yet their confidence estimates often lack calibration, limiting their reliability for biomedical applications. In this work, we introduce a new…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Francesco Campi , Lucrezia Tondo , Ekin Karabati , Johannes Betge , Marie Piraud

Annotation ambiguity due to inherent data uncertainties such as blurred boundaries in medical scans and different observer expertise and preferences has become a major obstacle for training deep-learning based medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Yicheng Wu , Xiangde Luo , Zhe Xu , Xiaoqing Guo , Lie Ju , Zongyuan Ge , Wenjun Liao , Jianfei Cai

There has recently been great progress in automatic segmentation of medical images with deep learning algorithms. In most works observer variation is acknowledged to be a problem as it makes training data heterogeneous but so far no…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Arkadiy Dushatskiy , Adriënne M. Mendrik , Peter A. N. Bosman , Tanja Alderliesten

Deep neural networks have achieved satisfactory performance in piles of medical image analysis tasks. However the training of deep neural network requires a large amount of samples with high-quality annotations. In medical image…

Computer Vision and Pattern Recognition · Computer Science 2020-07-08 Jixin Wang , Sanping Zhou , Chaowei Fang , Le Wang , Jinjun Wang

Multi-rater annotations commonly occur when medical images are independently annotated by multiple experts (raters). In this paper, we tackle two challenges arisen in multi-rater annotations for medical image segmentation (called ambiguous…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Jinhong Wang , Yi Cheng , Jintai Chen , Hongxia Xu , Danny Chen , Jian Wu

Deep learning has shown remarkable progress in medical image semantic segmentation, yet its success heavily depends on large-scale expert annotations and consistent data distributions. In practice, annotations are scarce, and images are…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Ba-Thinh Lam , Thanh-Huy Nguyen , Hoang-Thien Nguyen , Quang-Khai Bui-Tran , Nguyen Lan Vi Vu , Phat K. Huynh , Ulas Bagci , Min Xu

The success of deep learning methods in medical image segmentation tasks usually requires a large amount of labeled data. However, obtaining reliable annotations is expensive and time-consuming. Semi-supervised learning has attracted much…

Image and Video Processing · Electrical Eng. & Systems 2021-07-13 Yichi Zhang , Jicong Zhang

We tackle biomedical image segmentation in the scenario of only a few labeled brain MR images. This is an important and challenging task in medical applications, where manual annotations are time-consuming. Current multi-atlas based…

Computer Vision and Pattern Recognition · Computer Science 2020-01-14 Hyeon Woo Lee , Mert R. Sabuncu , Adrian V. Dalca

The performance of supervised deep learning methods for medical image segmentation is often limited by the scarcity of labeled data. As a promising research direction, semi-supervised learning addresses this dilemma by leveraging unlabeled…

Image and Video Processing · Electrical Eng. & Systems 2024-05-13 Zihang Liu , Chunhui Zhao

Fully supervised deep neural networks for segmentation usually require a massive amount of pixel-level labels which are manually expensive to create. In this work, we develop a multi-task learning method to relax this constraint. We regard…

Computer Vision and Pattern Recognition · Computer Science 2021-04-07 Rihuan Ke , Aurélie Bugeau , Nicolas Papadakis , Mark Kirkland , Peter Schuetz , Carola-Bibiane Schönlieb

Modern deep neural networks achieved remarkable progress in medical image segmentation tasks. However, it has recently been observed that they tend to produce overconfident estimates, even in situations of high uncertainty, leading to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-05 Agostina Larrazabal , Cesar Martinez , Jose Dolz , Enzo Ferrante

Recent advances in deep learning algorithms have led to significant benefits for solving many medical image analysis problems. Training deep learning models commonly requires large datasets with expert-labeled annotations. However,…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Banafshe Felfeliyan , Abhilash Hareendranathan , Gregor Kuntze , Stephanie Wichuk , Nils D. Forkert , Jacob L. Jaremko , Janet L. Ronsky

We systematically evaluate a Deep Learning (DL) method in a 3D medical image segmentation task. Our segmentation method is integrated into the radiosurgery treatment process and directly impacts the clinical workflow. With our method, we…

Image and Video Processing · Electrical Eng. & Systems 2021-08-24 Boris Shirokikh , Alexandra Dalechina , Alexey Shevtsov , Egor Krivov , Valery Kostjuchenko , Amayak Durgaryan , Mikhail Galkin , Andrey Golanov , Mikhail Belyaev

With the development of Deep Neural Networks (DNNs), many efforts have been made to handle medical image segmentation. Traditional methods such as nnUNet train specific segmentation models on the individual datasets. Plenty of recent…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Xiaobao Wei , Jiajun Cao , Yizhu Jin , Ming Lu , Guangyu Wang , Shanghang Zhang

Medical image segmentation is a fundamental and critical step in many image-guided clinical approaches. Recent success of deep learning-based segmentation methods usually relies on a large amount of labeled data, which is particularly…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Rushi Jiao , Yichi Zhang , Le Ding , Rong Cai , Jicong Zhang

Most of the state-of-the-art semantic segmentation reported in recent years is based on fully supervised deep learning in the medical domain. How?ever, the high-quality annotated datasets require intense labor and domain knowledge,…

Image and Video Processing · Electrical Eng. & Systems 2022-04-25 Pingping Dai , Haiming Zhu , Shuang Ge , Ruihan Zhang , Xiang Qian , Xi Li , Kehong Yuan

Deep learning algorithms have become the golden standard for segmentation of medical imaging data. In most works, the variability and heterogeneity of real clinical data is acknowledged to still be a problem. One way to automatically…

Image and Video Processing · Electrical Eng. & Systems 2022-02-25 Arkadiy Dushatskiy , Gerry Lowe , Peter A. N. Bosman , Tanja Alderliesten

Despite the superior performance of Deep Learning (DL) on numerous segmentation tasks, the DL-based approaches are notoriously overconfident about their prediction with highly polarized label probability. This is often not desirable for…

Image and Video Processing · Electrical Eng. & Systems 2021-12-14 Sungmin Hong , Anna K. Bonkhoff , Andrew Hoopes , Martin Bretzner , Markus D. Schirmer , Anne-Katrin Giese , Adrian V. Dalca , Polina Golland , Natalia S. Rost
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