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Alzheimer's disease is an untreatable, progressive brain disorder that slowly robs people of their memory, thinking abilities, and ultimately their capacity to complete even the most basic tasks. Among older adults, it is the most frequent…
Deep learning methods based on Convolutional Neural Networks (CNNs) have shown great potential to improve early and accurate diagnosis of Alzheimer's disease (AD) dementia based on imaging data. However, these methods have yet to be widely…
Diabetic retinopathy (DR) is the result of a complication of diabetes affecting the retina. It can cause blindness, if left undiagnosed and untreated. An ophthalmologist performs the diagnosis by screening each patient and analyzing the…
Alzheimer's disease (AD), the predominant form of dementia, is a growing global challenge, emphasizing the urgent need for accurate and early diagnosis. Current clinical diagnoses rely on radiologist expert interpretation, which is prone to…
This research paper addresses the critical challenge of diabetic retinopathy (DR), a severe complication of diabetes leading to potential blindness. The proposed methodology leverages transfer learning with convolutional neural networks…
We proposed a deep learning method for interpretable diabetic retinopathy (DR) detection. The visual-interpretable feature of the proposed method is achieved by adding the regression activation map (RAM) after the global averaging pooling…
Skin cancer, the most common human malignancy, is primarily diagnosed visually by physicians [1]. Classification with an automated method like CNN [2, 3] shows potential for challenging tasks [1]. By now, the deep convolutional neural…
Alzheimer's Disease (AD) causes a continuous decline in memory, thinking, and judgment. Traditional diagnoses are usually based on clinical experience, which is limited by some realistic factors. In this paper, we focus on exploiting deep…
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss, making effective prognosis crucial for timely intervention. In this work, we propose AMD-Mamba, a novel multi-modal framework for AMD prognosis, and…
Diabetic retinopathy and diabetic macular edema are significant complications of diabetes that can lead to vision loss. Early detection through ultra-widefield fundus imaging enhances patient outcomes but presents challenges in image…
Widespread outreach programs using remote retinal imaging have proven to decrease the risk from diabetic retinopathy, the leading cause of blindness in the US. However, this process still requires manual verification of image quality and…
Alzheimer's Disease is a neurodegenerative condition characterized by dementia and impairment in neurological function. The study primarily focuses on the individuals above age 40, affecting their memory, behavior, and cognitive processes…
The most frequent kind of dementia of the nervous system, Alzheimer's disease, weakens several brain processes (such as memory) and eventually results in death. The clinical study uses magnetic resonance imaging to diagnose AD. Deep…
We propose an automatic diabetic retinopathy (DR) analysis algorithm based on two-stages deep convolutional neural networks (DCNN). Compared to existing DCNN-based DR detection methods, the proposed algorithm have the following advantages:…
The differential diagnosis of neurodegenerative dementias is a challenging clinical task, mainly because of the overlap in symptom presentation and the similarity of patterns observed in structural neuroimaging. To improve diagnostic…
Background: Although convolutional neural networks (CNN) achieve high diagnostic accuracy for detecting Alzheimer's disease (AD) dementia based on magnetic resonance imaging (MRI) scans, they are not yet applied in clinical routine. One…
Despite strong performance of deep learning models in retinal disease detection, most systems produce static predictions without clinical reasoning or interactive explanation. Recent advances in multimodal large language models (MLLMs)…
Objective Reticular pseudodrusen (RPD), a key feature of age-related macular degeneration (AMD), are poorly detected by human experts on standard color fundus photography (CFP) and typically require advanced imaging modalities such as…
Melanoma is a type of skin cancer with the most rapidly increasing incidence. Early detection of melanoma using dermoscopy images significantly increases patients' survival rate. However, accurately classifying skin lesions by eye,…
The fast growing deep learning technologies have become the main solution of many machine learning problems for medical image analysis. Deep convolution neural networks (CNNs), as one of the most important branch of the deep learning…