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Decomposition plays a significant role in cooperative co-evolution which shows great potential in large scale black-box optimization. However, current popular decomposition algorithms generally require to sample and evaluate a large number…

Optimization and Control · Mathematics 2019-05-30 Zhigang Ren , An Chen , Yaochu Jin , Wenhua Guo , Yongsheng Liang , Zuren Feng

The recent trend towards Personalized Federated Learning (PFL) has garnered significant attention as it allows for the training of models that are tailored to each client while maintaining data privacy. However, current PFL techniques…

Machine Learning · Computer Science 2023-05-03 Yue Wu , Shuaicheng Zhang , Wenchao Yu , Yanchi Liu , Quanquan Gu , Dawei Zhou , Haifeng Chen , Wei Cheng

Drug-drug interaction (DDI) prediction is a critical task in computational biomedicine, as adverse interactions between co-administered drugs can cause severe side effects and clinical risks. A key challenge is unseen-drug generalization,…

Machine Learning · Computer Science 2026-05-15 Yerin Park , Sangseon Lee

Accurate prediction of Drug-Target Affinity (DTA) is crucial for reducing experimental costs and accelerating early screening in computational drug discovery. While sequence-based deep learning methods avoid reliance on costly 3D…

Machine Learning · Computer Science 2025-11-03 Minghui Li , Yuanhang Wang , Peijin Guo , Wei Wan , Shengshan Hu , Shengqing Hu

Distributed multi-target tracking (DMTT) is addressed for sensors having different fields of view (FoVs). The proposed approach is based on the idea of fusing the posterior Probability Hypotheses Densities (PHDs) generated by the sensors on…

Systems and Control · Computer Science 2019-08-28 Guchong Li , Giorgio Battistelli , Wei Yi , Lingjiang Kong

In this article we propose an improvement on the sequential updating and greedy search (SUGS) algorithm Wang and Dunson for fast fitting of Dirichlet process mixture models. The SUGS algorithm provides a means for very fast approximate…

Computation · Statistics 2015-05-01 David Nott , Xiaole Zhang , Chris Yau , Ajay Jasra

Fine-grained visual categorization (FGVC), which aims at classifying objects with small inter-class variances, has been significantly advanced in recent years. However, ultra-fine-grained visual categorization (ultra-FGVC), which targets at…

Computer Vision and Pattern Recognition · Computer Science 2021-10-28 Yajie Sun , Miaohua Zhang , Xiaohan Yu , Yi Liao , Yongsheng Gao

Learning feature interactions is crucial for click-through rate (CTR) prediction in recommender systems. In most existing deep learning models, feature interactions are either manually designed or simply enumerated. However, enumerating all…

Machine Learning · Computer Science 2020-07-06 Bin Liu , Chenxu Zhu , Guilin Li , Weinan Zhang , Jincai Lai , Ruiming Tang , Xiuqiang He , Zhenguo Li , Yong Yu

Drug-drug interactions (DDIs) remain a major source of preventable harm, and many clinically important mechanisms are still unknown. Existing models either rely on pharmacologic knowledge graphs (KGs), which fail on unseen drugs, or on…

Machine Learning · Computer Science 2025-11-11 Franklin Lee , Tengfei Ma

Recent years have witnessed the rapid accumulation of massive electronic medical records (EMRs), which highly support the intelligent medical services such as drug recommendation. However, prior arts mainly follow the traditional…

Information Retrieval · Computer Science 2021-02-09 Zhi Zheng , Chao Wang , Tong Xu , Dazhong Shen , Penggang Qin , Baoxing Huai , Tongzhu Liu , Enhong Chen

Conventional federated learning (FL) assumes a closed world with a fixed total number of clients. In contrast, new clients continuously join the FL process in real-world scenarios, introducing new knowledge. This raises two critical…

Machine Learning · Computer Science 2025-10-21 Zhengyi Zhong , Wenzheng Jiang , Weidong Bao , Ji Wang , Cheems Wang , Guanbo Wang , Yongheng Deng , Ju Ren

Gating modules have been widely explored in dynamic network pruning to reduce the run-time computational cost of deep neural networks while preserving the representation of features. Despite the substantial progress, existing methods remain…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Mengnan Shi , Chang Liu , Jianbin Jiao , Qixiang Ye

The drug discovery stage is a vital aspect of the drug development process and forms part of the initial stages of the development pipeline. In recent times, machine learning-based methods are actively being used to model drug-target…

Machine Learning · Computer Science 2020-09-02 Brighter Agyemang , Wei-Ping Wu , Michael Yelpengne Kpiebaareh , Zhihua Lei , Ebenezer Nanor , Lei Chen

The prediction of protein-ligand binding affinity is of great significance for discovering lead compounds in drug research. Facing this challenging task, most existing prediction methods rely on the topological and/or spatial structure of…

Biomolecules · Quantitative Biology 2022-09-28 Yang Zhang , Gengmo Zhou , Zhewei Wei , Hongteng Xu

Repetitive Transcranial Magnetic Stimulation (rTMS) is a well-supported, evidence-based treatment for depression. However, patterns of response to this treatment are inconsistent. Emerging evidence suggests that artificial intelligence can…

Machine Learning · Computer Science 2024-04-29 Matthew Squires , Xiaohui Tao , Soman Elangovan , Raj Gururajan , Haoran Xie , Xujuan Zhou , Yuefeng Li , U Rajendra Acharya

Similarity search, the task of identifying objects most similar to a given query object under a specific metric, has gathered significant attention due to its practical applications. However, the absence of coordinate information to…

Databases · Computer Science 2024-05-14 Yifan Zhu , Ruiyao Ma , Baihua Zheng , Xiangyu Ke , Lu Chen , Yunjun Gao

Generative Retrieval (GR) has emerged as a promising paradigm to unify indexing and search within a single probabilistic framework. However, existing approaches suffer from two intrinsic conflicts: (1) an Optimization Blockage, where the…

Information Retrieval · Computer Science 2026-03-12 Xujing Wang , Yufeng Chen , Boxuan Zhang , Jie Zhao , Chao Wei , Cai Xu , Ziyu Guan , Wei Zhao , Weiru Zhang , Xiaoyi Zeng

Fine-Grained Change Detection and Regression Analysis are essential in many applications of ArtificialIntelligence. In practice, this task is often challenging owing to the lack of reliable ground truth information andcomplexity arising…

Machine Learning · Computer Science 2022-08-12 Niall O' Mahony , Sean Campbell , Lenka Krpalkova , Joseph Walsh , Daniel Riordan

The identification of compound-protein interactions (CPI) plays a critical role in drug screening, drug repurposing, and combination therapy studies. The effectiveness of CPI prediction relies heavily on the features extracted from both…

Biomolecules · Quantitative Biology 2023-06-16 Li Zhang , Wenhao Li , Haotian Guan , Zhiquan He , Mingjun Cheng , Han Wang

Recent advancements in integrating tactile sensing into vision-language-action (VLA) models have demonstrated transformative potential for robotic perception. However, existing tactile representations predominantly rely on qualitative…

Robotics · Computer Science 2026-03-12 Wenxuan Ma , Chaofan Zhang , Yinghao Cai , Guocai Yao , Shaowei Cui , Shuo Wang