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Text Generation aims to produce plausible and readable text in a human language from input data. The resurgence of deep learning has greatly advanced this field, in particular, with the help of neural generation models based on pre-trained…

Computation and Language · Computer Science 2022-05-17 Junyi Li , Tianyi Tang , Wayne Xin Zhao , Jian-Yun Nie , Ji-Rong Wen

The rapid advancement of large language models (LLMs) has revolutionized natural language processing, enabling applications in diverse domains such as healthcare, finance and education. However, the growing reliance on extensive data for…

Cryptography and Security · Computer Science 2024-12-10 Guoshenghui Zhao , Eric Song

Large language models (LLMs) have demonstrated strong performance in a wide-range of language tasks without requiring task-specific fine-tuning. However, they remain prone to hallucinations and inconsistencies, and often struggle with…

Computation and Language · Computer Science 2026-03-27 Matt Pauk , Maria Leonor Pacheco

The advent of Large Language Models (LLMs) provides an opportunity to change the way queries are processed, moving beyond the constraints of conventional SQL-based database systems. However, using an LLM to answer a prediction query is…

Information Retrieval · Computer Science 2024-09-04 Ziyu Li , Wenjie Zhao , Asterios Katsifodimos , Rihan Hai

The springing up of Large Language Models (LLMs) has shifted the community from single-task-orientated natural language processing (NLP) research to a holistic end-to-end multi-task learning paradigm. Along this line of research endeavors…

Computation and Language · Computer Science 2023-10-31 Yuanfeng Song , Yuanqin He , Xuefang Zhao , Hanlin Gu , Di Jiang , Haijun Yang , Lixin Fan , Qiang Yang

Protein language models (PLMs) learn probability distributions over natural protein sequences. By learning from hundreds of millions of natural protein sequences, protein understanding and design capabilities emerge. Recent works have shown…

Quantitative Methods · Quantitative Biology 2026-02-27 Timothy Fei Truong , Tristan Bepler

The potential of deep learning has been recognized in the protein structure prediction community for some time, and became indisputable after CASP13. In CASP14, deep learning has boosted the field to unanticipated levels reaching…

Biomolecules · Quantitative Biology 2021-09-14 Elodie Laine , Stephan Eismann , Arne Elofsson , Sergei Grudinin

Computational models starting from large ensembles of evolutionarily related protein sequences capture a representation of protein families and learn constraints associated to protein structure and function. They thus open the possibility…

Biomolecules · Quantitative Biology 2024-12-30 Damiano Sgarbossa , Umberto Lupo , Anne-Florence Bitbol

We are now witnessing significant progress of deep learning methods in a variety of tasks (or datasets) of proteins. However, there is a lack of a standard benchmark to evaluate the performance of different methods, which hinders the…

Machine Learning · Computer Science 2022-09-20 Minghao Xu , Zuobai Zhang , Jiarui Lu , Zhaocheng Zhu , Yangtian Zhang , Chang Ma , Runcheng Liu , Jian Tang

Large Language Models (LLMs) have recently demonstrated remarkable capabilities in natural language processing tasks and beyond. This success of LLMs has led to a large influx of research contributions in this direction. These works…

Computation and Language · Computer Science 2024-10-18 Humza Naveed , Asad Ullah Khan , Shi Qiu , Muhammad Saqib , Saeed Anwar , Muhammad Usman , Naveed Akhtar , Nick Barnes , Ajmal Mian

Background: Identification of the interactions and regulatory relations between biomolecules play pivotal roles in understanding complex biological systems and the mechanisms underlying diverse biological functions. However, the collection…

Computation and Language · Computer Science 2025-04-24 Gilchan Park , Byung-Jun Yoon , Xihaier Luo , Vanessa López-Marrero , Shinjae Yoo , Shantenu Jha

A plethora of protein language models have been released in recent years. Yet comparatively little work has addressed how to best sample from them to optimize desired biological properties. We fill this gap by proposing a flexible,…

Machine Learning · Computer Science 2026-05-08 Calvin McCarter , Nick Bhattacharya , Sebastian W. Ober , Hunter Elliott

Many machine learning applications require the ability to learn from and reason about noisy multi-relational data. To address this, several effective representations have been developed that provide both a language for expressing the…

Artificial Intelligence · Computer Science 2012-03-19 Matthias Brocheler , Lilyana Mihalkova , Lise Getoor

Pre-trained language models (PLMs) have outperformed other NLP models on a wide range of tasks. Opting for a more thorough understanding of their capabilities and inner workings, researchers have established the extend to which they capture…

Computation and Language · Computer Science 2022-11-09 Anne Lauscher , Federico Bianchi , Samuel Bowman , Dirk Hovy

Representation learning for proteins has primarily focused on the global understanding of protein sequences regardless of their length. However, shorter proteins (known as peptides) take on distinct structures and functions compared to…

Quantitative Methods · Quantitative Biology 2022-11-15 Gil Sadeh , Zichen Wang , Jasleen Grewal , Huzefa Rangwala , Layne Price

Large language models (LLMs) have shown promise in various natural language processing tasks, including their application to proteomics data to classify protein fragments. In this study, we curated a limited mass spectrometry dataset with…

Quantitative Methods · Quantitative Biology 2025-02-28 Taylor A Phillips , Alejandro W. Huskey , Patrick T. Huskey , Seth L. Robia , Peter M. Kekenes-Huskey

In recent years, large language models (LLMs) have achieved remarkable success in natural language processing (NLP). LLMs require an extreme amount of parameters to attain high performance. As models grow into the trillion-parameter range,…

Computation and Language · Computer Science 2024-09-10 Zhyar Rzgar K Rostam , Sándor Szénási , Gábor Kertész

Sequential recommendation (SR) has seen significant advancements with the help of Pre-trained Language Models (PLMs). Some PLM-based SR models directly use PLM to encode user historical behavior's text sequences to learn user…

Information Retrieval · Computer Science 2024-08-15 Zekai Qu , Ruobing Xie , Chaojun Xiao , Xingwu Sun , Zhanhui Kang

In recent years, there has been remarkable progress in leveraging Language Models (LMs), encompassing Pre-trained Language Models (PLMs) and Large-scale Language Models (LLMs), within the domain of mathematics. This paper conducts a…

Computation and Language · Computer Science 2025-01-03 Wentao Liu , Hanglei Hu , Jie Zhou , Yuyang Ding , Junsong Li , Jiayi Zeng , Mengliang He , Qin Chen , Bo Jiang , Aimin Zhou , Liang He

This paper provides a comprehensive survey of the latest research on multilingual large language models (MLLMs). MLLMs not only are able to understand and generate language across linguistic boundaries, but also represent an important…

Computation and Language · Computer Science 2024-11-20 Shaolin Zhu , Supryadi , Shaoyang Xu , Haoran Sun , Leiyu Pan , Menglong Cui , Jiangcun Du , Renren Jin , António Branco , Deyi Xiong
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