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Magnetic resonance imaging (MRI) is a remarkably powerful diagnostic technique: it generates wide-ranging information for the non-invasive study of tissue anatomy and physiology. Complementary data is normally obtained in separate…

Image and Video Processing · Electrical Eng. & Systems 2019-01-24 Pedro A. Gómez , Miguel Molina-Romero , Guido Buonincontri , Marion I. Menzel , Bjoern H. Menze

This paper introduces a computationally efficient technique for estimating high-resolution Doppler blood flow from an ultrafast ultrasound image sequence. More precisely, it consists in a new fast alternating minimization algorithm that…

Image and Video Processing · Electrical Eng. & Systems 2020-11-04 Duong-Hung Pham , Adrian Basarab , Jean-Pierre Remenieras , Paul Rodríguez , Denis Kouamé

Quantitative phase imaging (QPI) is a label-free technique that provides optical path length information for transparent specimens, finding utility in biology, materials science, and engineering. Here, we present quantitative phase imaging…

Dynamic susceptibility-weighted contrast-enhanced (DSC) MRI or perfusion-MRI plays an important role in the non-invasive assessment of tumor vascularity. However, the large number of images provided by the method makes display and…

General Physics · Physics 2007-11-20 Friso Hoefnagels , Keith S Cover , Ester Sanchez , Frank J. Lagerwaard

Scene parsing has attracted a lot of attention in computer vision. While parametric models have proven effective for this task, they cannot easily incorporate new training data. By contrast, nonparametric approaches, which bypass any…

Computer Vision and Pattern Recognition · Computer Science 2016-03-16 Mohammad Najafi , Sarah Taghavi Namin , Mathieu Salzmann , Lars Petersson

Bacterial infectious diseases are a major threat to human health. Timely and sensitive pathogenic bacteria detection is crucial in identifying the bacterial contaminations and preventing the spread of infectious diseases. Due to limitations…

Primary neuronal cultures have been widely used to study neuronal morphology, neurophysiology, neurodegenerative processes, and molecular mechanism of synaptic plasticity underlying learning and memory. Yet, the unique behavioral properties…

Image and Video Processing · Electrical Eng. & Systems 2020-08-04 Mikhail E. Kandel , Eunjae Kim , Young Jae Lee , Gregory Tracy , Hee Jung Chung , Gabriel Popescu

Holotomography (HT) has revolutionized quantitative label-free 3D imaging, yet conventional lens-based implementations are fundamentally constrained in field-of-view (FOV) and imaging depth, limiting their utility for critical…

Intracardiac flow patterns are shaped by the coupled motion of the cardiac chambers and heart valves and provide important information about cardiac function. However, clinical flow imaging remains limited by exam times, noise, resolution,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Fanwei Kong , Aaron Brown , Michael Loecher , Perry S. Choi , Lei Shi , Michael Ma , Daniel B. Ennis , Alison Marsden

In applications of optical multipass cells in photochemical reactors and laser excitation of weak transitions, estimation of the radiation dose in a volume of interest allows to assess the performance and optimize the design of the cell. We…

We demonstrate experimentally quantum-inspired, spectral-domain intensity optical coherence tomography. We show that the technique allows for both axial resolution improvement and dispersion cancellation compared to conventional optical…

Optics · Physics 2015-03-16 Piotr Ryczkowski , Jari Turunen , Ari T. Friberg , Goëry Genty

High throughput real-time instruments are needed to acquire large data sets for detection and classification of rare events. Enabled by the photonic time stretch digitizer, a new class of instruments with record throughputs have led to the…

Optics · Physics 2015-03-20 Bahram Jalali , Ata Mahjoubfar , Claire L. Chen

In this work, we demonstrated on-chip label-free imaging microscopy using real and Fourier Plane (FP) microscopic dark field images of Surface Plasmons (SP), excited on engineered 1D and 2D low aspect ratio periodic plasmonic…

Applied Physics · Physics 2018-02-13 P. Arora , A. Krishnan

We report on wide-field imaging of pulsatile motion induced by blood flow using heterodyne holographic interferometry on the thumb of a healthy volunteer, in real-time. Optical Doppler images were measured with green laser light by a…

Time-resolved spectral techniques play an important analysis tool in many contexts, from physical chemistry to biomedicine. Customarily, the label-free detection of analytes is manually performed by experts through the aid of classic…

Machine Learning · Computer Science 2020-11-17 Stefano Rini , Hirotsugu Hiramatsu

Microfluidic devices are increasingly used in synchrotron-based experiments to deliver and probe liquid samples, offering advantages such as minimal sample consumption and reduced radiation damage. Despite their growing use, few devices…

Dynamic full-field optical coherence microscopy (d-FF-OCM) is a label-free imaging technique that captures intrinsic subcellular motions to generate functional contrast. This dynamic approach yields images with fluorescence-like contrast,…

Optics · Physics 2025-08-06 Erikas Tarvydas , Austeja Treciokaite , Egidijus Auksorius

Optical detection of individual nanometer-sized analytes, virus particles, and protein molecules holds great promise for understanding and control of biological samples and healthcare applications. As fluorescent labels impose restrictions…

Optics · Physics 2020-10-19 Martin Dieter Baaske , Peter Sebastian Neu , Michel Orrit

Correlative microscopy is a powerful technique that combines the advantages of multiple imaging modalities to achieve a comprehensive understanding of investigated samples. For example, fluorescence microscopy provides unique functional…

Reflection phase imaging provides label-free, high-resolution characterization of biological samples, typically using interferometric-based techniques. Here, we investigate reflection phase microscopy from intensity-only measurements under…

Quantitative Methods · Quantitative Biology 2019-12-18 Alex Matlock , Anne Sentenac , Patrick C. Chaumet , Ji Yi , Lei Tian
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