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In this paper, we apply statistical methods for functional data to explain the heterogeneity in the evolution of number of deaths of Covid-19 over different regions. We treat the cumulative daily number of deaths in a specific region as a…

Applications · Statistics 2021-09-07 Julian A. A. Collazos , Ronaldo Dias , Marcelo C. Medeiros

Understanding the spread of COVID-19 has been the subject of numerous studies, highlighting the significance of reliable epidemic models. Here, we introduce a novel epidemic model using a latent Hawkes process with temporal covariates for…

Methodology · Statistics 2022-08-16 Stamatina Lamprinakou , Axel Gandy , Emma McCoy

Nowcasting and forecasting of epidemic spreading rely on incidence series of reported cases to derive the fundamental epidemiological parameters for a given pathogen. Two relevant drawbacks for predictions are the unknown fractions of…

Populations and Evolution · Quantitative Biology 2022-08-31 Guilherme S. Costa , Wesley Cota , Silvio C. Ferreira

Compartmental models like the Susceptible-Infected-Recovered (SIR)\cite{Kermack1927} and its extensions such as the Susceptible-Exposed-Infected-Recovered (SEIRS)\cite{Ottar2020,Ignazio2021,Grimm2021,Paoluzzi2021} are commonly used to model…

Populations and Evolution · Quantitative Biology 2025-07-14 Kasturi Banerjee , Subhankar Ray , Jayalakshmi Shamanna

Modelling the transmission dynamics of an infectious disease is a complex task. Not only it is difficult to accurately model the inherent non-stationarity and heterogeneity of transmission, but it is nearly impossible to describe,…

Computation · Statistics 2023-07-19 Sanmitra Ghosh , Paul J. Birrell , Daniela De Angelis

The COVID-19 pandemic has significantly challenged traditional epidemiological models due to factors such as delayed diagnosis, asymptomatic transmission, isolation-induced contact changes, and underreported mortality. In response to these…

Applications · Statistics 2025-03-10 Wenchen Liu , Chang Liu , Dehui Wang , Yiyuan She

Over the course of the COVID-19 pandemic, Generalised Additive Models (GAMs) have been successfully employed on numerous occasions to obtain vital data-driven insights. In this paper we further substantiate the success story of GAMs,…

Emerging in December 2019, the COVID-19 pandemic caused widespread health, economic, and social disruptions. Rapid global transmission overwhelmed healthcare systems, resulting in high infection rates, hospitalisations, and fatalities. To…

Populations and Evolution · Quantitative Biology 2025-10-08 Zacharias Komodromos , Kleanthis Malialis , Panayiotis Kolios

Spatio-temporal models for infection counts generally follow themes of the broader disease mapping literature, but may need to address specific features of spatio-temporal infection data including considerable time fluctuations (with…

Applications · Statistics 2022-02-22 P. Congdon

Although there is substantial literature on identifying structural changes for continuous spatio-temporal processes, the same is not true for categorical spatio-temporal data. This work bridges that gap and proposes a novel spatio-temporal…

Methodology · Statistics 2023-05-04 Siddharth Rawat , Abe Durrant , Adam Simpson , Grant Nielson , Candace Berrett , Soudeep Deb

The COVID-19 infection fatality rate (IFR) is the proportion of individuals infected with SARS-CoV-2 who subsequently die. As COVID-19 disproportionately affects older individuals, age-specific IFR estimates are imperative to facilitate…

Genetic sequence data of pathogens are increasingly used to investigate transmission dynamics in both endemic diseases and disease outbreaks; such research can aid in development of appropriate interventions and in design of studies to…

Quantitative Methods · Quantitative Biology 2018-01-24 Hesam Montazeri , Susan Little , Niko Beerenwinkel , Victor DeGruttola

Infectious diseases that incorporate pre-symptomatic transmission are challenging to monitor, model, predict and contain. We address this scenario by studying a variant of a stochastic susceptible-exposed-infected-recovered model on…

Physics and Society · Physics 2021-05-07 Bo Li , David Saad

A diffusive epidemic model with an infection-dependent recovery rate is formulated in this paper. Multiple constant steady states and spatially homogeneous periodic solutions are first proven by bifurcation analysis of the reaction…

Dynamical Systems · Mathematics 2025-09-12 Wael El Khateeb , Chanaka Kottegoda , Chunhua Shan

It has long been known that epidemics can travel along communication lines, such as roads. In the current COVID-19 epidemic, it has been observed that major roads have enhanced its propagation in Italy. We propose a new simple model of…

Analysis of PDEs · Mathematics 2020-11-16 Henri Berestycki , Jean-Michel Roquejoffre , Luca Rossi

Epidemiological models with constant parameters may not capture satisfactory infection patterns in the presence of pharmaceutical and non-pharmaceutical mitigation measures during a pandemic, since infectiousness is a function of time. In…

Populations and Evolution · Quantitative Biology 2022-05-16 K. D. Olumoyin , A. Q. M. Khaliq , K. M. Furati

The COVID-19 pandemic has presented unprecedented challenges worldwide, necessitating effective modelling approaches to understand and control its transmission dynamics. In this study, we propose a novel approach that integrates…

Populations and Evolution · Quantitative Biology 2025-01-14 Moein Khalighi , Leo Lahti , Faïçal Ndaïrou , Peter Rashkov , Delfim F. M. Torres

Two stochastic models are proposed to describe the evolution of the COVID-19 pandemic. In the first model the population is partitioned into four compartments: susceptible $S$, infected $I$, removed $R$ and dead people $D$. In order to have…

Populations and Evolution · Quantitative Biology 2021-09-16 Fabiana Calleri , Giovanni Nastasi , Vittorio Romano

Large-scale testing is considered key to assess the state of the current COVID-19 pandemic. Yet, the link between the reported case numbers and the true state of the pandemic remains elusive. We develop mathematical models based on…

Applications · Statistics 2021-02-04 Michel Besserve , Simon Buchholz , Bernhard Schölkopf

Epidemiological models describe the spread of an infectious disease within a population. They capture microscopic details on how the disease is passed on among individuals in various different ways, while making predictions about the state…

Populations and Evolution · Quantitative Biology 2024-02-27 Stefan Hohenegger , Francesco Sannino