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Medical image segmentation plays a crucial role in clinical workflows, but domain shift often leads to performance degradation when models are applied to unseen clinical domains. This challenge arises due to variations in imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Yingkai Wang , Yaoyao Zhu , Xiuding Cai , Yuhao Xiao , Haotian Wu , Yu Yao

In search of robust and generalizable machine learning models, Domain Generalization (DG) has gained significant traction during the past few years. The goal in DG is to produce models which continue to perform well when presented with data…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Aristotelis Ballas , Christos Diou

Medical image segmentation models often struggle to generalize across different domains due to various reasons. Domain Generalization (DG) methods overcome this either through representation learning or data augmentation (DAug). While…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Piyush Tiwary , Kinjawl Bhattacharyya , Prathosh A. P

A desirable property of any deployed artificial intelligence is generalization across domains, i.e. data generation distribution under a specific acquisition condition. In medical imagining applications the most coveted property for…

Image and Video Processing · Electrical Eng. & Systems 2026-01-26 Ayan Banerjee , Komandoor Srivathsan , Sandeep K. S. Gupta

The task of single-source domain generalization (SDG) in medical image segmentation is crucial due to frequent domain shifts in clinical image datasets. To address the challenge of poor generalization across different domains, we introduce…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Haoyu Zhao , Wenhui Dong , Rui Yu , Zhou Zhao , Du Bo , Yongchao Xu

Data augmentation (DA) has been widely leveraged in computer vision to alleviate data shortage, while its application in medical imaging faces multiple challenges. The prevalent DA approaches in medical image analysis encompass conventional…

Image and Video Processing · Electrical Eng. & Systems 2026-03-26 Zhaoshan Liu , Qiujie Lv , Yifan Li , Ziduo Yang , Lei Shen

Single domain generalization (Single-DG) intends to develop a generalizable model with only one single training domain to perform well on other unknown target domains. Under the domain-hungry configuration, how to expand the coverage of…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Jian Xu , Chaojie Ji , Yankai Cao , Ye Li , Ruxin Wang

Domain shifts in medical image segmentation, particularly when data comes from different centers, pose significant challenges. Intra-center variability, such as differences in scanner models or imaging protocols, can cause domain shifts as…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jin Hong , Bo Liu

Recently deep learning methods, in particular, convolutional neural networks (CNNs), have led to a massive breakthrough in the range of computer vision. Also, the large-scale annotated dataset is the essential key to a successful training…

Image and Video Processing · Electrical Eng. & Systems 2020-11-17 Chang Qi , Junyang Chen , Guizhi Xu , Zhenghua Xu , Thomas Lukasiewicz , Yang Liu

As a recent noticeable topic, domain generalization (DG) aims to first learn a generic model on multiple source domains and then directly generalize to an arbitrary unseen target domain without any additional adaption. In previous DG…

Computer Vision and Pattern Recognition · Computer Science 2022-02-17 Yue Wang , Lei Qi , Yinghuan Shi , Yang Gao

State-of-the-art stereo matching (SM) models trained on synthetic data often fail to generalize to real data domains due to domain differences, such as color, illumination, contrast, and texture. To address this challenge, we leverage data…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Shuangli Du , Jing Wang , Minghua Zhao , Zhenyu Xu , Jie Li

Domain generalization typically requires data from multiple source domains for model learning. However, such strong assumption may not always hold in practice, especially in medical field where the data sharing is highly concerned and…

Computer Vision and Pattern Recognition · Computer Science 2022-06-30 Quande Liu , Cheng Chen , Qi Dou , Pheng-Ann Heng

The recent prevalence of deep neural networks has lead semantic segmentation networks to achieve human-level performance in the medical field when sufficient training data is provided. Such networks however fail to generalize when tasked…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Serban Stan , Mohammad Rostami

Deep learning has achieved remarkable success in medical image classification. However, its clinical application is often hindered by data heterogeneity caused by variations in scanner vendors, imaging protocols, and operators. Approaches…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Yaoyao Zhu , Xiuding Cai , Yingkai Wang , Yu Yao , Xu Luo , Zhongliang Fu

Machine learning models are intrinsically vulnerable to domain shift between training and testing data, resulting in poor performance in novel domains. Domain generalization (DG) aims to overcome the problem by leveraging multiple source…

Computer Vision and Pattern Recognition · Computer Science 2022-10-27 Tingwei Wang , Da Li , Kaiyang Zhou , Tao Xiang , Yi-Zhe Song

Deep learning-based models in medical imaging often struggle to generalize effectively to new scans due to data heterogeneity arising from differences in hardware, acquisition parameters, population, and artifacts. This limitation presents…

Image and Video Processing · Electrical Eng. & Systems 2023-08-09 Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

Data augmentation for domain-specific image classification tasks often struggles to simultaneously address diversity, faithfulness, and label clarity of generated data, leading to suboptimal performance in downstream tasks. While existing…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Yixuan Dong , Fang-Yi Su , Jung-Hsien Chiang

Robust cardiac image segmentation is still an open challenge due to the inability of the existing methods to achieve satisfactory performance on unseen data of different domains. Since the acquisition and annotation of medical data are…

Image and Video Processing · Electrical Eng. & Systems 2020-08-27 Xiao Liu , Spyridon Thermos , Agisilaos Chartsias , Alison O'Neil , Sotirios A. Tsaftaris

Data augmentation has been widely applied as an effective methodology to improve generalization in particular when training deep neural networks. Recently, researchers proposed a few intensive data augmentation techniques, which indeed…

Machine Learning · Computer Science 2019-11-22 Zhuoxun He , Lingxi Xie , Xin Chen , Ya Zhang , Yanfeng Wang , Qi Tian

Domain Generalization (DG) aims to train models that can generalize to unseen testing domains by leveraging data from multiple training domains. However, traditional DG methods rely on the availability of multiple diverse training domains,…

Machine Learning · Computer Science 2025-03-11 Hao Yan , Marzi Heidari , Yuhong Guo