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Whole slide imaging is fundamental to biomedical microscopy and computational pathology. Previously, learning representations for gigapixel-sized whole slide images (WSIs) has relied on multiple instance learning with weak labels, which do…

Computer Vision and Pattern Recognition · Computer Science 2024-05-27 Xinhai Hou , Cheng Jiang , Akhil Kondepudi , Yiwei Lyu , Asadur Chowdury , Honglak Lee , Todd C. Hollon

This paper presents a simple yet effective two-stage framework for semi-supervised medical image segmentation. Unlike prior state-of-the-art semi-supervised segmentation methods that predominantly rely on pseudo supervision directly on…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Huimin Wu , Xiaomeng Li , Kwang-Ting Cheng

Deep neural networks often struggle to learn robust representations in the presence of dataset biases, leading to suboptimal generalization on unbiased datasets. This limitation arises because the models heavily depend on peripheral and…

Machine Learning · Computer Science 2024-12-11 Carlo Alberto Barbano , Enzo Tartaglione , Marco Grangetto

Until recently, the number of public real-world text images was insufficient for training scene text recognizers. Therefore, most modern training methods rely on synthetic data and operate in a fully supervised manner. Nevertheless, the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-10 Aviad Aberdam , Roy Ganz , Shai Mazor , Ron Litman

Deep neural networks need a big amount of training data, while in the real world there is a scarcity of data available for training purposes. To resolve this issue unsupervised methods are used for training with limited data. In this…

Computer Vision and Pattern Recognition · Computer Science 2022-02-10 Sayed Hashim , Muhammad Ali

This paper demonstrates a self-supervised framework for learning voxel-wise coarse-to-fine representations tailored for dense downstream tasks. Our approach stems from the observation that existing methods for hierarchical representation…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Eytan Kats , Jochen G. Hirsch , Mattias P. Heinrich

Recent breakthroughs in self-supervised learning have enabled the use of large unlabeled datasets to train visual foundation models that can generalize to a variety of downstream tasks. While this training paradigm is well suited for the…

In healthcare and biomedical applications, extreme computational requirements pose a significant barrier to adopting representation learning. Representation learning can enhance the performance of deep learning architectures by learning…

Machine Learning · Computer Science 2023-08-22 Pranav Singh , Jacopo Cirrone

This paper introduces a new concept called "transferable visual words" (TransVW), aiming to achieve annotation efficiency for deep learning in medical image analysis. Medical imaging--focusing on particular parts of the body for defined…

Computer Vision and Pattern Recognition · Computer Science 2021-02-23 Fatemeh Haghighi , Mohammad Reza Hosseinzadeh Taher , Zongwei Zhou , Michael B. Gotway , Jianming Liang

Vessel segmentation is an essential task in many clinical applications. Although supervised methods have achieved state-of-art performance, acquiring expert annotation is laborious and mostly limited for two-dimensional datasets with a…

Image and Video Processing · Electrical Eng. & Systems 2021-07-23 Rohit Jena , Sumedha Singla , Kayhan Batmanghelich

Machine-learning-assisted cancer subtyping is a promising avenue in digital pathology. Cancer subtyping models, however, require careful training using expert annotations so that they can be inferred with a degree of known certainty (or…

Recent advances in self-supervised learning (SSL) using large models to learn visual representations from natural images are rapidly closing the gap between the results produced by fully supervised learning and those produced by SSL on…

Computer Vision and Pattern Recognition · Computer Science 2022-11-03 Weiyao Wang , Byung-Hak Kim , Varun Ganapathi

Pre-training lays the foundation for recent successes in radiograph analysis supported by deep learning. It learns transferable image representations by conducting large-scale fully-supervised or self-supervised learning on a source domain.…

Image and Video Processing · Electrical Eng. & Systems 2022-01-28 Hong-Yu Zhou , Xiaoyu Chen , Yinghao Zhang , Ruibang Luo , Liansheng Wang , Yizhou Yu

Medical image segmentation remains challenging in low-data regimes, where scarce annotations often yield poor generalization and ambiguous boundaries with missing fine structures. Recent self-supervised pretraining has improved…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Zhiquan Chen , Haitao Wang , Guowei Zou , Hejun Wu

Self-supervised learning has greatly facilitated medical image analysis by suppressing the training data requirement for real-world applications. Current paradigms predominantly rely on self-supervision within uni-modal image data, thereby…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Shaohao Rui , Lingzhi Chen , Zhenyu Tang , Lilong Wang , Mianxin Liu , Shaoting Zhang , Xiaosong Wang

Foundation models in healthcare have largely adopted self supervised pretraining objectives inherited from natural language processing and computer vision, emphasizing reconstruction and large scale representation learning prior to…

Machine Learning · Computer Science 2026-03-24 Yang Zhang , Li Fan , Samuel Lawrence , Shi Li

Supervised learning-based segmentation methods typically require a large number of annotated training data to generalize well at test time. In medical applications, curating such datasets is not a favourable option because acquiring a large…

Image and Video Processing · Electrical Eng. & Systems 2020-11-20 Krishna Chaitanya , Neerav Karani , Christian F. Baumgartner , Ertunc Erdil , Anton Becker , Olivio Donati , Ender Konukoglu

Unsupervised representation learning aims at finding methods that learn representations from data without annotation-based signals. Abstaining from annotations not only leads to economic benefits but may - and to some extent already does -…

Computer Vision and Pattern Recognition · Computer Science 2023-12-04 Bonifaz Stuhr

Traditional supervised learning with deep neural networks requires a tremendous amount of labelled data to converge to a good solution. For 3D medical images, it is often impractical to build a large homogeneous annotated dataset for a…

Multimodal self-supervised pretraining offers a promising route to cancer prognosis by integrating histopathology whole-slide images, gene expression, and pathology reports, yet most existing approaches require fully paired and complete…

Machine Learning · Computer Science 2026-04-08 Kai Yu , Shuang Zhou , Yiran Song , Zaifu Zhan , Jie Peng , Kaixiong Zhou , Tianlong Chen , Feng Xie , Meng Wang , Huazhu Fu , Mingquan Lin , Rui Zhang
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