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Related papers: Joint Cryo-ET Alignment and Reconstruction with Ne…

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Cryo-electron microscopy (cryo-EM) has revolutionized structural biology by enabling near-atomic-level visualization of biomolecular assemblies. However, the exponential growth in cryo-EM data throughput and complexity, coupled with diverse…

Quantitative Methods · Quantitative Biology 2026-02-25 Weining Fu , Kai Shu , Kui Xu , Qiangfeng Cliff Zhang

In the past decade, deep conditional generative models have revolutionized the generation of realistic images, extending their application from entertainment to scientific domains. Single-particle cryo-electron microscopy (cryo-EM) is…

Computer Vision and Pattern Recognition · Computer Science 2024-10-01 Jiakai Zhang , Qihe Chen , Yan Zeng , Wenyuan Gao , Xuming He , Zhijie Liu , Jingyi Yu

Single particle electron cryomicroscopy (cryo-EM) allows for structures of proteins and protein complexes to be determined from images of non-crystalline specimens. Cryo-EM data analysis requires electron microscope images of randomly…

Instrumentation and Detectors · Physics 2015-11-23 Jianhua Zhao , Marcus A. Brubaker , Samir Benlekbir , John L. Rubinstein

Cryo-electron microscopy (cryo-EM) has emerged as a powerful technique for determining the three-dimensional structures of biological molecules at near-atomic resolution. However, reconstructing helical assemblies presents unique challenges…

Quantitative Methods · Quantitative Biology 2026-03-16 Guy Shapira , Yoel Shkolnisky

Blind deconvolution aims to recover an original image from a blurred version in the case where the blurring kernel is unknown. It has wide applications in diverse fields such as astronomy, microscopy, and medical imaging. Blind…

Numerical Analysis · Mathematics 2024-02-06 Markus Haltmeier , Gyeongha Hwang

X-ray tomography has been studied in various fields. Although a great deal of effort has been directed at reconstructing the projection image set from a rigid-type specimen, little attention has been addressed to the reconstruction of…

Computational Physics · Physics 2018-07-04 Kyungtaek Jun , Dongwook Kim

We propose a method to non-rigidly align a three-dimensional (3D) volumetric image with a two-dimensional (2D) planar image representing a projection of the deformed volume. The application in mind comes from biological studies in which 2D…

Optimization and Control · Mathematics 2021-01-12 Paul Striewski , Benedikt Wirth

Multiple approaches to use deep learning for image restoration have recently been proposed. Training such approaches requires well registered pairs of high and low quality images. While this is easily achievable for many imaging modalities,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Tim-Oliver Buchholz , Mareike Jordan , Gaia Pigino , Florian Jug

In tomographic reconstruction, the goal is to reconstruct an unknown object from a collection of line integrals. Given a complete sampling of such line integrals for various angles and directions, explicit inverse formulas exist to…

Numerical Analysis · Mathematics 2018-01-18 Tristan van Leeuwen , Simon Maretzke , K. Joost Batenburg

Computed Tomography (CT) is an essential non-destructive three dimensional imaging modality used in medicine, security screening, and inspection of manufactured components. Typical CT data acquisition entails the collection of a thousand or…

Medical Physics · Physics 2024-10-11 Kyle M. Champley , Michael B. Zellner , Joseph W. Tringe , Harry E. Martz

Joint ptychography and tomography (JPT) is a recently developed framework that enables high-resolution reconstruction of 3D volumes with significantly relaxed constraints on probe overlap at adjacent scan positions. In ptychographic X-ray…

Image and Video Processing · Electrical Eng. & Systems 2020-02-20 Azat M. Slyamov , Viktor Nikitin , Doğa Gürsoy , Rajmund Mokso , Jens W. Andreasen

Computed Tomography (CT) reconstruction is a fundamental component to a wide variety of applications ranging from security, to healthcare. The classical techniques require measuring projections, called sinograms, from a full 180$^\circ$…

Computer Vision and Pattern Recognition · Computer Science 2018-07-12 Rushil Anirudh , Hyojin Kim , Jayaraman J. Thiagarajan , K. Aditya Mohan , Kyle Champley , Timo Bremer

We study a class of orbit recovery problems in which we observe independent copies of an unknown element of $\mathbb{R}^p$, each linearly acted upon by a random element of some group (such as $\mathbb{Z}/p$ or $\mathrm{SO}(3)$) and then…

Statistics Theory · Mathematics 2023-06-26 Afonso S. Bandeira , Ben Blum-Smith , Joe Kileel , Amelia Perry , Jonathan Niles-Weed , Alexander S. Wein

Most of the classical denoising methods restore clear results by selecting and averaging pixels in the noisy input. Instead of relying on hand-crafted selecting and averaging strategies, we propose to explicitly learn this process with deep…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Xiangyu Xu , Muchen Li , Wenxiu Sun

A common task in cryo-electron microscopy (cryo-EM) data processing is to compare three-dimensional density maps of macromolecules. In this paper, we propose an algorithm for aligning three-dimensional density maps that exploits common…

Image and Video Processing · Electrical Eng. & Systems 2023-02-27 Yael Harpaz , Yoel Shkolnisky

This paper introduces a deep neural network based method, i.e., DeepOrganNet, to generate and visualize high-fidelity 3D / 4D organ geometric models from single-view medical image in real time. Traditional 3D / 4D medical image…

Graphics · Computer Science 2019-07-23 Yifan Wang , Zichun Zhong , Jing Hua

In this paper, we study the problem of reconstructing a 3D point source model from a set of 2D projections at unknown view angles. Our method obviates the need to recover the projection angles by extracting a set of rotation-invariant…

Signal Processing · Electrical Eng. & Systems 2020-03-24 Mona Zehni , Shuai Huang , Ivan Dokmanić , Zhizhen Zhao

This paper presents a novel approach to reconstruct complete 3D deformable models over time by a single depth camera. These are the steps employed for deforming objects from single depth camera. The partial surfaces reconstructed from…

Computer Vision and Pattern Recognition · Computer Science 2017-08-31 Vamshhi Pavan Kumar Varma Vegeshna

Cryogenic electron microscopy (cryo-EM) is an invaluable technique for determining high-resolution three-dimensional structures of biological macromolecules using transmission particle images. The inherent symmetry in these macromolecules…

Optimization and Control · Mathematics 2024-11-06 Qi Zhang , Chenglong Bao , Hai Lin , Mingxu Hu

In this work we present a novel approach for computing correspondences between non-rigid objects, by exploiting a reduced representation of deformation fields. Different from existing works that represent deformation fields by training a…

Computer Vision and Pattern Recognition · Computer Science 2022-11-29 Ramana Sundararaman , Riccardo Marin , Emanuele Rodola , Maks Ovsjanikov
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