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Non-invasive colorectal cancer (CRC) screening represents a key opportunity to improve colonoscopy participation rates and reduce CRC mortality. This study explores the potential of the gut-liver axis for predicting colorectal neoplasia…

Objectives: The role of advanced diffusion-weighted imaging (DWI) in chronic liver disease (CLD) has not been fully studied. Chronic liver disease (CLD) is a progressive deterioration of liver functions, caused by one or more etiology. This…

Tissues and Organs · Quantitative Biology 2025-09-10 Jiqing Huang , Benjamin Leporq , Valérie Hervieu , Sophie Gaillard , Jerome Dumortier , Olivier Beuf , Hélène Ratiney

Purpose: To identify optimal classification methods for computed tomography (CT) radiomics-based preoperative prediction of clear cells renal cell carcinoma (ccRCC) grade. Methods and material: Seventy one ccRCC patients were included in…

Accurate three-dimensional delineation of liver tumors on contrast-enhanced CT is a prerequisite for treatment planning, navigation and response assessment, yet manual contouring is slow, observer-dependent and difficult to standardise…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Xuecheng Li , Weikuan Jia , Komildzhon Sharipov , Alimov Ruslan , Lutfuloev Mazbutdzhon , Ismoilov Shuhratjon , Yuanjie Zheng

Background: The high dimensionality of radiomic feature sets, the variability in radiomic feature types and potentially high computational requirements all underscore the need for an effective method to identify the smallest set of…

This study aimed to develop a machine learning (ML) algorithm capable of determining cardiovascular risk in multimodal retinal images from patients with type 1 diabetes mellitus, distinguishing between moderate, high, and very high-risk…

Ultrasound (US) is a critical modality for diagnosing liver fibrosis. Unfortunately, assessment is very subjective, motivating automated approaches. We introduce a principled deep convolutional neural network (CNN) workflow that…

Image and Video Processing · Electrical Eng. & Systems 2020-08-11 Bowen Li , Ke Yan , Dar-In Tai , Yuankai Huo , Le Lu , Jing Xiao , Adam P. Harrison

Establishing the reproducibility of radiomic signatures is a critical step in the path to clinical adoption of quantitative imaging biomarkers; however, radiomic signatures must also be meaningfully related to an outcome of clinical…

Background: Liver diseases present a significant global health challenge and often require costly, invasive diagnostics. Electrocardiography (ECG), a widely available and non-invasive tool, can enable the detection of liver disease by…

Machine Learning · Computer Science 2025-05-21 Juan Miguel Lopez Alcaraz , Wilhelm Haverkamp , Nils Strodthoff

Objectives: High-grade serous ovarian carcinoma (HGSOC) is typically diagnosed at an advanced stage with extensive peritoneal metastases, making treatment challenging. Neoadjuvant chemotherapy (NACT) is often used to reduce tumor burden…

Objectives: Glioblastomas are the most aggressive brain and central nervous system (CNS) tumors with poor prognosis in adults. The purpose of this study is to develop a machine-learning based classification method using radio-mic features…

Medical Physics · Physics 2019-11-25 Ge Cui , Jiwoong Jeong , Bob Press , Yang Lei , Hui-Kuo Shu , Tian Liu , Walter Curran , Hui Mao , Xiaofeng Yang

Aimed to develop and validate a CT radiomics-based explainable machine learning model for precise diagnosing malignancy and benignity specifically in endometrial cancer (EC) patients. A total of 83 EC patients from two centers, including 46…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Tingrui Zhang , Honglin Wu , Zekun Jiang , Yingying Wang , Rui Ye , Huiming Ni , Chang Liu , Jin Cao , Xuan Sun , Rong Shao , Xiaorong Wei , Yingchun Sun

With a high rate of morbidity and mortality, colorectal cancer (CRC) ranks third in mortality among cancers. By analyzing the texture properties of images and quantifying the heterogeneity of tumors, radiomics and radiogenomics are…

Medical Physics · Physics 2024-06-25 Parsa Karami , Reza Elahi

Pathologies systematically induce morphological changes, thus providing a major but yet insufficiently quantified source of observables for diagnosis. The study develops a predictive model of the pathological states based on morphological…

Background: We aim to develop enriched radiomics features that integrate classical structural radiomics with novel functional radiomics derived from liver MRI for diagnosis and risk stratification in liver cancer. The proposed framework…

Uterine leiomyosarcoma (LMS) is a rare but aggressive malignancy. On imaging, it is difficult to differentiate LMS from, for example, degenerated leiomyoma (LM), a prevalent but benign condition. We curated a data set of 115 axial…

Lung cancer is the leading cause of cancer death in the world. Accurate determination of the EGFR (epidermal growth factor receptor) mutation status is highly relevant for the proper treatment of this patients. Purpose: The aim of this…

Quantitative Methods · Quantitative Biology 2023-03-16 Hector Henriquez , Diana Fuentes , Francisco Suarez , Patricio Gonzalez

Radiomics is an active area of research focusing on high throughput feature extraction from medical images with a wide array of applications in clinical practice, such as clinical decision support in oncology. However, noise in low dose…

Quantitative Methods · Quantitative Biology 2021-09-07 Junhua Chen , Inigo Bermejo , Andre Dekker , Leonard Wee

Objective: Radiomics, an emerging tool for medical image analysis, is potential towards precisely characterizing gastric cancer (GC). Whether using one-slice 2D annotation or whole-volume 3D annotation remains a long-time debate, especially…

Image and Video Processing · Electrical Eng. & Systems 2022-11-01 Lingwei Meng , Di Dong , Xin Chen , Mengjie Fang , Rongpin Wang , Jing Li , Zaiyi Liu , Jie Tian

Non-invasive radiological-based lesion characterization and identification, e.g., to differentiate cancer subtypes, has long been a major aim to enhance oncological diagnosis and treatment procedures. Here we study a specific population of…

Computer Vision and Pattern Recognition · Computer Science 2020-09-01 Yuankai Huo , Jinzheng Cai , Chi-Tung Cheng , Ashwin Raju , Ke Yan , Bennett A. Landman , Jing Xiao , Le Lu , Chien-Hung Liao , Adam P. Harrison
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