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We present a proof-of-principle study demonstrating the use of large language model (LLM) agents to automate a representative high energy physics (HEP) analysis. Using the Higgs boson diphoton cross-section measurement as a case study with…

Data Analysis, Statistics and Probability · Physics 2025-12-10 Eli Gendreau-Distler , Joshua Ho , Dongwon Kim , Luc Tomas Le Pottier , Haichen Wang , Chengxi Yang

The Forelem framework was first introduced as a means to optimize database queries using optimization techniques developed for compilers. Since its introduction, Forelem has proven to be more versatile and to be applicable beyond database…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-03-03 A. Hommelberg , B. van Strien , K. F. D. Rietveld , H. A. G. Wijshoff

High Energy Physics (HEP) experiments, for example at the Large Hadron Collider (LHC) at CERN, store data at exabyte scale in sets of files. They use a binary columnar data format by the ROOT framework, that also transparently compresses…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-10-21 Jonas Hahnfeld , Jakob Blomer , Thorsten Kollegger

High-energy physics (HEP) experiments have developed millions of lines of code over decades that are optimized to run on traditional x86 CPU systems. However, we are seeing a rapidly increasing fraction of floating point computing power in…

The challenge to fully exploit the potential of existing and upcoming scientific instruments like large single-dish radio telescopes is to process the collected massive data effectively and efficiently. As a "quasi 2D stencil computation"…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-07-12 Hao Wang , Ce Yu , Jian Xiao , Shanjiang Tang , Min Long , Ming Zhu

Fully Homomorphic Encryption (FHE) allows for computation directly on encrypted data and enables privacy-preserving neural inference in the cloud. Prior work has focused on models with dense inputs (e.g., CNNs), with less attention given to…

Cryptography and Security · Computer Science 2026-02-23 Karthik Garimella , Austin Ebel , Gabrielle De Micheli , Brandon Reagen

We describe the plans and objectives of the CEDAR project (Combined e-Science Data Analysis Resource for High Energy Physics) newly funded by the PPARC e-Science programme in the UK. CEDAR will combine the strengths of the well established…

High Energy Physics - Phenomenology · Physics 2007-05-23 J. M. Butterworth , S. Butterworth , B. M. Waugh , W. J. Stirling , M. R. Whalley

Realistic environments for prototyping, studying and improving analysis workflows are a crucial element on the way towards user-friendly physics analysis at HL-LHC scale. The IRIS-HEP Analysis Grand Challenge (AGC) provides such an…

High Energy Physics - Experiment · Physics 2024-01-08 Alexander Held , Elliott Kauffman , Oksana Shadura , Andrew Wightman

ROOT is an object-oriented C++ framework conceived in the high-energy physics (HEP) community, designed for storing and analyzing petabytes of data in an efficient way. Any instance of a C++ class can be stored into a ROOT file in a…

The LHCb experiment at CERN has undergone a comprehensive upgrade, including a complete re-design of the trigger system into a hybrid-architecture, software-only system that delivers ten times more interesting signals per unit time than its…

Instrumentation and Detectors · Physics 2025-03-26 Luke Grazette , Ross Hunter , Ella Noomen , Nicole Skidmore , Sascha Stahl , Mika Vesterinen , Shunan Zhang

The field of edge computing has witnessed remarkable growth owing to the increasing demand for real-time processing of data in applications. However, challenges persist due to limitations in performance and power consumption. To overcome…

Hardware Architecture · Computer Science 2024-03-11 Simone Machetti , Pasquale Davide Schiavone , Thomas Christoph Müller , Miguel Peón-Quirós , David Atienza

Let's HPC (www.letshpc.org) is an open-access online platform to supplement conventional classroom oriented High Performance Computing (HPC) and Parallel & Distributed Computing (PDC) education. The web based platform provides online…

Computers and Society · Computer Science 2017-01-24 Akshar Varma , Yashwant Keswani , Yashodhan Bhatnagar , Bhaskar Chaudhury

With the LHC continuing to collect more data and experimental analyses becoming increasingly complex, tools to efficiently develop and execute these analyses are essential. The bamboo framework defines a domain-specific language, embedded…

Data Analysis, Statistics and Probability · Physics 2021-08-24 Pieter David

Dynamic programming (DP) based algorithms are essential yet compute-intensive parts of numerous bioinformatics pipelines, which typically involve populating a 2-D scoring matrix based on a recursive formula, optionally followed by a…

Hardware Architecture · Computer Science 2024-11-07 Yingqi Cao , Anshu Gupta , Jason Liang , Yatish Turakhia

The Large Hadron Collider (LHC) machine at CERN was designed and built primarily to find or exclude the existence of the Higgs boson, for which a large amount of data is needed by the LHC experiments. This requires operation at high…

Accelerator Physics · Physics 2014-04-04 R. Bailey

In recent times, the emergence of Large Language Models (LLMs) has resulted in increasingly larger model size, posing challenges for inference on low-resource devices. Prior approaches have explored offloading to facilitate low-memory…

Performance · Computer Science 2024-03-05 Xuanlei Zhao , Bin Jia , Haotian Zhou , Ziming Liu , Shenggan Cheng , Yang You

As the scientific community continues to push the boundaries of computing capabilities, there is a growing responsibility to address the associated energy consumption and carbon footprint. This responsibility extends to the Worldwide LHC…

The scale of scientific High Performance Computing (HPC) and High Throughput Computing (HTC) has increased significantly in recent years, and is becoming sensitive to total energy use and cost. Energy-efficiency has thus become an important…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-10-14 David Abdurachmanov , Peter Elmer , Giulio Eulisse , Robert Knight , Tapio Niemi , Jukka K. Nurminen , Filip Nyback , Goncalo Pestana , Zhonghong Ou , Kashif Khan

In recent years, language models (LMs), such as GPT-4, have been widely used in multiple domains, including natural language processing, visualization, and so on. However, applying them for analyzing and optimizing high-performance…

Machine Learning · Computer Science 2023-11-28 Le Chen , Pei-Hung Lin , Tristan Vanderbruggen , Chunhua Liao , Murali Emani , Bronis de Supinski

Hyperdimensional Computing (HDC), a technique inspired by cognitive models of computation, has been proposed as an efficient and robust alternative basis for machine learning. HDC programs are often manually written in low-level and target…

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