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A variety of enhanced sampling methods predict multidimensional free energy landscapes associated with biological and other molecular processes as a function of a few selected collective variables (CVs). The accuracy of these methods is…

Computational Physics · Physics 2024-04-09 Lukas Müllender , Andrea Rizzi , Michele Parrinello , Paolo Carloni , Davide Mandelli

Generating energy functions for heterogeneous systems suitable for quantitative and predictive atomistic simulations is a challenging undertaking. The present work combines a cluster-based approach with electronic structure calculations at…

Chemical Physics · Physics 2025-03-03 Kai Töpfer , Jingchun Wang , Shimoni Patel , Markus Meuwly

Combustion stabilization and enhancement of the flammability limits are mandatory objectives to improve nowadays combustion chambers. At this purpose, the use of an electric field in the flame region provides a solution which is, at the…

Fluid Dynamics · Physics 2017-12-13 M. Di Renzo , P. De Palma , M. D. de Tullio , G. Pascazio

Quantum embedding approaches involve the self-consistent optimization of a local fragment of a strongly correlated system, entangled with the wider environment. The `energy-weighted' density matrix embedding theory (EwDMET) was established…

Strongly Correlated Electrons · Physics 2021-02-23 P. V. Sriluckshmy , Max Nusspickel , Edoardo Fertitta , George H. Booth

High-fidelity simulations are essential for predicting material behavior under high-velocity impact (HVI), but their accuracy depends on material models and parameters that are often calibrated by manual fitting to multiple costly…

Materials Science · Physics 2026-04-01 Rong Jin , Guangyao Wang , Xingsheng Sun

Nuclear quantum effects (NQEs) are often central to a predictive understanding of chemical reactions and rates. While their incorporation in gas-phase reactions is well established, studies involving condensed matter often neglect or…

Chemical Physics · Physics 2026-03-12 Jalen Macatangay , Alejandro Strachan

Quantum many-body methods provide a systematic route to computing electronic properties of molecules and materials, but high computational costs restrict their use in large-scale applications. Due to the complexity in many-electron…

The present work focuses on the large eddy simulation (LES) and the study of turbulent dilute methanol spray flames in vitiated coflow using the secondary oxidizer Flamelet Generated Model (FGM). The modified FGM model uses an additional…

Fluid Dynamics · Physics 2022-08-25 Bharat Bhatia , Ashoke De , Dirk Roekaerts , Assaad R. Masri

Recent progress in machine learning (ML) has made high-accuracy quantum chemistry (QC) calculations more accessible. Of particular interest are multifidelity machine learning (MFML) methods where training data from differing accuracies or…

Chemical Physics · Physics 2025-03-26 Vivin Vinod , Peter Zaspel

Transformations of covariates are widely used in applied statistics to improve interpretability and to satisfy assumptions required for valid inference. More broadly, feature engineering encompasses a wider set of practices aimed at…

Methodology · Statistics 2026-03-30 Claudia Collarin , Matteo Fasiolo , Yannig Goude , Simon N. Wood

Free energies are fundamental quantities governing phase behavior and thermodynamic stability in polymer systems, yet their accurate computation often requires extensive simulations and post-processing techniques such as the Bennett…

Soft Condensed Matter · Physics 2026-03-19 Ian Chen , Alfredo Alexander-Katz

In the current study, the influence of turbulent mixing and local reaction rates on deflagration to detonation transition (DDT) was investigated using a state-of-the-art large eddy simulation (LES) strategy. Specifically, detonation…

Fluid Dynamics · Physics 2017-08-10 Brian Maxwell , Andrzej Pekalski , Matei Radulescu

We propose a methodology for fully automated calculation of thermal rate coefficients of gas phase chemical reactions, which is based on combining the ring polymer molecular dynamics (RPMD) with the machine-learning interatomic potentials…

Chemical Physics · Physics 2018-12-26 Ivan S. Novikov , Yury V. Suleimanov , Alexander V. Shapeev

Because of the impact of extreme heat waves and heat domes on society and biodiversity, their study is a key challenge. We specifically study long-lasting extreme heat waves, which are among the most important for climate impacts. Physics…

Machine Learning · Computer Science 2022-01-14 Valérian Jacques-Dumas , Francesco Ragone , Pierre Borgnat , Patrice Abry , Freddy Bouchet

We propose a machine learning framework based on Flow Matching (FM) to identify critical properties in many-body systems efficiently. Using the 2D XY model as a benchmark, we demonstrate that a single network, trained only on configurations…

Statistical Mechanics · Physics 2026-01-06 Qian-Rui Lee , Daw-Wei Wang

The high computational cost of ab-initio methods limits their application in predicting electronic properties at the device scale. Therefore, an efficient method is needed to map the atomic structure to the electronic structure quickly.…

Materials Science · Physics 2025-09-09 Yunlong Wang , Zhixin Liang , Chi Ding , Junjie Wang , Zheyong Fan , Hui-Tian Wang , Dingyu Xing , Jian Sun

Striving to define very accurate vertical transition energies, we perform both high-level coupled cluster (CC) calculations (up to CCSDTQP) and selected configuration interaction (sCI) calculations (up to several millions of determinants)…

This work examines the physical consistency of the conventional Flamelet Progress Variable (FPV) model for diffusion flame simulations and and introduces a new compressible flamelet formulation that employs the turbulent kinetic energy…

Fluid Dynamics · Physics 2026-04-01 Sylvain L. Walsh , Yalu Zhu , Feng Liu , William A. Sirignano

Density estimation is a central primitive in probabilistic modeling, yet continuous, discrete, and mixed-variable domains are often treated by separate objectives, limiting the ability to exploit a common statistical structure across data…

Artificial Intelligence · Computer Science 2026-05-12 Zhijun Zeng , Yixuan Jiang , Pipi Hu , Zuoqiang Shi

Quantum simulators offer a new opportunity for the experimental exploration of non-equilibrium quantum many-body dynamics, which have traditionally been characterized through expectation values or entanglement measures, based on density…

Quantum Physics · Physics 2025-06-27 Zhiguang Yan , Zi-Yong Ge , Rui Li , Yu-Ran Zhang , Franco Nori , Yasunobu Nakamura
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