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The objective of many high-dimensional microarray and RNA-seq studies is to develop a classifier of cancer patients based on characteristics of their disease. The germinal center B-cell (GCB) classifier study in lymphoma and the National…
Improving the performance of click-through rate (CTR) prediction remains one of the core tasks in online advertising systems. With the rise of deep learning, CTR prediction models with deep networks remarkably enhance model capacities. In…
Scene-aware Adaptive Compressive Sensing (ACS) has attracted significant interest due to its promising capability for efficient and high-fidelity acquisition of scene images. ACS typically prescribes adaptive sampling allocation (ASA) based…
Confounding pathology with normal anatomical variation remains a significant challenge in unsupervised medical-image anomaly detection, resulting in numerous false positives. To enhance integration of healthy variation, we augment the…
In epidemiology research with cancer registry data, it is often of primary interest to make inference on cancer death, not overall survival. Since cause of death is not easy to collect or is not necessarily reliable in cancer registries,…
Node classification using Graph Neural Networks (GNNs) has been widely applied in various practical scenarios, such as predicting user interests and detecting communities in social networks. However, recent studies have shown that…
Compressed sensing (sparse signal recovery) has been a popular and important research topic in recent years. By observing that natural signals are often nonnegative, we propose a new framework for nonnegative signal recovery using…
The proliferation of wireless communications has recently created a bottleneck in terms of spectrum availability. Motivated by the observation that the root of the spectrum scarcity is not a lack of resources but an inefficient managing…
Background: Accurate detection of QRS complexes during mobile, ultra-long-term ECG monitoring is challenged by instances of high heart rate, dramatic and persistent changes in signal amplitude, and intermittent deformations in signal…
Cancer subtyping plays a crucial role in informing prognosis and guiding personalized treatment strategies. However, conventional subtyping approaches often rely on static, biopsy-derived scores that hardly capture the biological…
Reachability analysis is at the core of many applications, from neural network verification, to safe trajectory planning of uncertain systems. However, this problem is notoriously challenging, and current approaches tend to be either too…
Sampling of signals belonging to a low-dimensional subspace has well-documented merits for dimensionality reduction, limited memory storage, and online processing of streaming network data. When the subspace is known, these signals can be…
Graph contrastive learning has emerged as a powerful tool for unsupervised graph representation learning. The key to the success of graph contrastive learning is to acquire high-quality positive and negative samples as contrasting pairs for…
Extracting associations that recur across multiple studies while controlling the false discovery rate is a fundamental challenge. Here, we consider an extension of Efron's single-study two-groups model to allow joint analysis of multiple…
Image-based sequencing of mRNA makes it possible to see where in a tissue sample a given gene is active, and thus discern large numbers of different cell types in parallel. This is crucial for gaining a better understanding of tissue…
Electrocardiogram (ECG) signal is the most commonly used non-invasive tool in the assessment of cardiovascular diseases. Segmentation of the ECG signal to locate its constitutive waves, in particular the R-peaks, is a key step in ECG…
Cancer survival prediction is an active area of research that can help prevent unnecessary therapies and improve patient's quality of life. Gene expression profiling is being widely used in cancer studies to discover informative biomarkers…
Controlled branching processes are stochastic growth population models in which the number of individuals with reproductive capacity in each generation is controlled by a random control function. The purpose of this work is to examine the…
This work considers the problem of detecting signals from multiple sequentially observed data streams, where only one stream can be observed at every time instant. The goal is to detect signals as quickly as possible while controlling the…
Multi-arm trials are gaining interest in practice given the statistical and logistical advantages they can offer. The standard approach uses a fixed allocation ratio, but there is a call for making it adaptive and skewing the allocation of…