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The emergence of multi-parametric magnetic resonance imaging (mpMRI) has had a profound impact on the diagnosis of prostate cancers (PCa), which is the most prevalent malignancy in males in the western world, enabling a better selection of…

The detection of clinically significant prostate cancer lesions (csPCa) from biparametric magnetic resonance imaging (bp-MRI) has emerged as a noninvasive imaging technique for improving accurate diagnosis. Nevertheless, the analysis of…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Mateo Ortiz , Juan Olmos , Fabio Martínez

Purpose: We aimed to develop deep machine learning (DL) models to improve the detection and segmentation of intraprostatic lesions (IL) on bp-MRI by using whole amount prostatectomy specimen-based delineations. We also aimed to investigate…

Image and Video Processing · Electrical Eng. & Systems 2020-10-30 Zhenzhen Dai , Ivan Jambor , Pekka Taimen , Milan Pantelic , Mohamed Elshaikh , Craig Rogers , Otto Ettala , Peter Boström , Hannu Aronen , Harri Merisaari , Ning Wen

Prostate radiotherapy is a well established curative oncology modality, which in future will use Magnetic Resonance Imaging (MRI)-based radiotherapy for daily adaptive radiotherapy target definition. However the time needed to delineate the…

Image and Video Processing · Electrical Eng. & Systems 2020-11-17 David Gillespie , Connah Kendrick , Ian Boon , Cheng Boon , Tim Rattay , Moi Hoon Yap

Histology review is often used as the `gold standard' for disease diagnosis. Computer aided diagnosis tools can potentially help improve current pathology workflows by reducing examination time and interobserver variability. Previous work…

Computer Vision and Pattern Recognition · Computer Science 2019-05-31 Jiayun Li , Wenyuan Li , Arkadiusz Gertych , Beatrice S. Knudsen , William Speier , Corey W. Arnold

Histology-based grade classification is clinically important for many cancer types in stratifying patients distinct treatment groups. In prostate cancer, the Gleason score is a grading system used to measure the aggressiveness of prostate…

Computer Vision and Pattern Recognition · Computer Science 2019-11-07 Jingwen Wang , Richard J. Chen , Ming Y. Lu , Alexander Baras , Faisal Mahmood

Worldwide, prostate cancer is one of the main cancers affecting men. The final diagnosis of prostate cancer is based on the visual detection of Gleason patterns in prostate biopsy by pathologists. Computer-aided-diagnosis systems allow to…

Computer Vision and Pattern Recognition · Computer Science 2020-05-26 Amartya Kalapahar , Julio Silva-Rodríguez , Adrián Colomer , Fernando López-Mir , Valery Naranjo

Accurate segmentation of the prostate gland in multiparametric MRI (mpMRI) is a fundamental step for a wide range of clinical and research applications, including image registration, volume estimation, and radiomic analysis. However, manual…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Pablo Rodriguez-Belenguer , Gloria Ribas , Javier Aquerreta Escribano , Rafael Moreno-Calatayud , Leonor Cerda-Alberich , Luis Marti-Bonmati

Prostate cancer (PCa) is one of the most common and aggressive cancers worldwide. The Gleason score (GS) system is the standard way of classifying prostate cancer and the most reliable method to determine the severity and treatment to…

Computer Vision and Pattern Recognition · Computer Science 2021-03-05 Santiago Toledo-Cortés , Diego H. Useche , Fabio A. González

Prostate cancer (PCa) is the most prevalent cancer among men in the United States, accounting for nearly 300,000 cases, 29\% of all diagnoses and 35,000 total deaths in 2024. Traditional screening methods such as prostate-specific antigen…

Image and Video Processing · Electrical Eng. & Systems 2025-05-27 Jarett Dewbury , Chi-en Amy Tai , Alexander Wong

Current deep learning-based models typically analyze medical images in either 2D or 3D albeit disregarding volumetric information or suffering sub-optimal performance due to the anisotropic resolution of MR data. Furthermore, providing an…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Alex Ling Yu Hung , Haoxin Zheng , Kai Zhao , Kaifeng Pang , Demetri Terzopoulos , Kyunghyun Sung

Dose escalation radiotherapy allows increased control of prostate cancer (PCa) but requires segmentation of dominant index lesions (DIL), motivating the development of automated methods for fast, accurate, and consistent segmentation of PCa…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Josiah Simeth , Jue Jiang , Anton Nosov , Andreas Wibmer , Michael Zelefsky , Neelam Tyagi , Harini Veeraraghavan

Semantic segmentation constitutes an integral part of medical image analyses for which breakthroughs in the field of deep learning were of high relevance. The large number of trainable parameters of deep neural networks however renders them…

Computer Vision and Pattern Recognition · Computer Science 2017-02-28 Simon Kohl , David Bonekamp , Heinz-Peter Schlemmer , Kaneschka Yaqubi , Markus Hohenfellner , Boris Hadaschik , Jan-Philipp Radtke , Klaus Maier-Hein

Prostate cancer is the most common cancer in men worldwide and the second leading cause of cancer death in the United States. One of the prognostic features in prostate cancer is the Gleason grading of histopathology images. The Gleason…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Mohammad Mahdi Behzadi , Mohammad Madani , Hanzhang Wang , Jun Bai , Ankit Bhardwaj , Anna Tarakanova , Harold Yamase , Ga Hie Nam , Sheida Nabavi

The diagnosis of prostate cancer faces a problem with overdiagnosis that leads to damaging side effects due to unnecessary treatment. Research has shown that the use of multi-parametric magnetic resonance images to conduct biopsies can…

Image and Video Processing · Electrical Eng. & Systems 2021-06-04 Pedro C. Neto

Prostate cancer (PCa) is the most common cancer in men in the United States. Multiparametic magnetic resonance imaging (mp-MRI) has been explored by many researchers to targeted prostate biopsies and radiation therapy. However, assessment…

Computer Vision and Pattern Recognition · Computer Science 2019-04-05 Zhenzhen Dai , Eric Carver , Chang Liu , Joon Lee , Aharon Feldman , Weiwei Zong , Milan Pantelic , Mohamed Elshaikh , Ning Wen

Prostate cancer is one of the common diseases in men, and it is the most common malignant tumor in developed countries. Studies have shown that the male prostate incidence rate is as high as 2.5% to 16%, Currently, the inci-dence of…

Image and Video Processing · Electrical Eng. & Systems 2019-12-23 Xiangxiang Qin

In this work, we propose a deep U-Net based model to tackle the challenging task of prostate cancer segmentation by aggressiveness in MRI based on weak scribble annotations. This model extends the size constraint loss proposed by Kervadec…

Image and Video Processing · Electrical Eng. & Systems 2022-07-13 Audrey Duran , Gaspard Dussert , Carole Lartizien

Automated prostate segmentation in MRI is highly demanded for computer-assisted diagnosis. Recently, a variety of deep learning methods have achieved remarkable progress in this task, usually relying on large amounts of training data. Due…

Image and Video Processing · Electrical Eng. & Systems 2020-02-20 Quande Liu , Qi Dou , Lequan Yu , Pheng Ann Heng

The large number of trainable parameters of deep neural networks renders them inherently data hungry. This characteristic heavily challenges the medical imaging community and to make things even worse, many imaging modalities are ambiguous…

Neural and Evolutionary Computing · Computer Science 2017-11-29 Simon Kohl , David Bonekamp , Heinz-Peter Schlemmer , Kaneschka Yaqubi , Markus Hohenfellner , Boris Hadaschik , Jan-Philipp Radtke , Klaus Maier-Hein
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