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The integration of multi-modal data, such as pathological images and genomic data, is essential for understanding cancer heterogeneity and complexity for personalized treatments, as well as for enhancing survival predictions. Despite the…

Quantitative Methods · Quantitative Biology 2023-01-09 Lin Qiu , Aminollah Khormali , Kai Liu

A significant advancement in bioinformatics is using genome graph techniques to improve variation discovery across organisms. Traditional approaches, such as bwa mem, rely on linear reference genomes for genomic analyses but may introduce…

Genomics · Quantitative Biology 2025-05-14 Fathima Nuzla Ismail , Abira Sengupta

In network embedding, random walks play a fundamental role in preserving network structures. However, random walk based embedding methods have two limitations. First, random walk methods are fragile when the sampling frequency or the number…

Machine Learning · Computer Science 2018-05-14 Yong Shi , Minglong Lei , Peng Zhang , Lingfeng Niu

In this paper, we present a novel approach based on the random walk process for finding meaningful representations of a graph model. Our approach leverages the transient behavior of many short random walks with novel initialization…

Social and Information Networks · Computer Science 2018-05-14 Lin Li , William M. Campbell , Rajmonda S. Caceres

The development of Graph Neural Networks (GNNs) has led to great progress in machine learning on graph-structured data. These networks operate via diffusing information across the graph nodes while capturing the structure of the graph.…

Machine Learning · Computer Science 2021-01-05 Shiv Shankar , Don Towsley

A system level view of cellular processes for human and several organisms can be cap- tured by analyzing molecular interaction networks. A molecular interaction network formed of differentially expressed genes and their interactions helps…

Molecular Networks · Quantitative Biology 2016-11-09 Jeethu V. Devasia , Priya Chandran

Flow and multicomponent reactive transport in saturated/unsaturated porous media are modeled by ensembles of computational particles moving on regular lattices according to specific random walk rules. The occupation number of the lattice…

Numerical Analysis · Mathematics 2022-07-27 Nicolae Suciu , Florin A. Radu

We revisit a simple model class for machine learning on graphs, where a random walk on a graph produces a machine-readable record, and this record is processed by a deep neural network to directly make vertex-level or graph-level…

Machine Learning · Computer Science 2025-03-06 Jinwoo Kim , Olga Zaghen , Ayhan Suleymanzade , Youngmin Ryou , Seunghoon Hong

The human connectome at the level of fiber tracts between brain regions has been shown to differ in patients with brain disorders compared to healthy control groups. Nonetheless, there is a potentially large number of different network…

Neurons and Cognition · Quantitative Biology 2013-10-16 Marcus Kaiser

Graph embedding has recently gained momentum in the research community, in particular after the introduction of random walk and neural network based approaches. However, most of the embedding approaches focus on representing the local…

Machine Learning · Computer Science 2020-02-19 Joerg Schloetterer , Martin Wehking , Fatemeh Salehi Rizi , Michael Granitzer

Analysis of social networks with limited data access is challenging for third parties. To address this challenge, a number of studies have developed algorithms that estimate properties of social networks via a simple random walk. However,…

Social and Information Networks · Computer Science 2023-05-23 Kazuki Nakajima , Kazuyuki Shudo

Random walk in random environment (RWRE) is a fundamental model of statistical mechanics, describing the movement of a particle in a highly disordered and inhomogeneous medium as a random walk with random jump probabilities. It has been…

Probability · Mathematics 2013-09-11 Alexander Drewitz , Alejandro F. Ramírez

We study the dynamics of a radioactive species flowing through a porous material, within the Continuous-Time Random Walk (CTRW) approach to the modelling of stochastic transport processes. Emphasis is given to the case where radioactive…

Statistical Mechanics · Physics 2008-05-17 A. Zoia

Many natural and artificial networks evolve in time. Nodes and connections appear and disappear at various timescales, and their dynamics has profound consequences for any processes in which they are involved. The first empirical analysis…

Statistical Mechanics · Physics 2012-05-21 Michele Starnini , Andrea Baronchelli , Alain Barrat , Romualdo Pastor-Satorras

Document networks are found in various collections of real-world data, such as citation networks, hyperlinked web pages, and online social networks. A large number of generative models have been proposed because they offer intuitive and…

Physics and Society · Physics 2020-01-22 Takafumi J. Suzuki

In the last twenty years network science has proven its strength in modelling many real-world interacting systems as generic agents, the nodes, connected by pairwise edges. Yet, in many relevant cases, interactions are not pairwise but…

Physics and Society · Physics 2020-02-26 Timoteo Carletti , Federico Battiston , Giulia Cencetti , Duccio Fanelli

The advent of high--throughput transcription profiling technologies has enabled identification of genes and pathways associated with disease, providing new avenues for precision medicine. A key challenge is to analyze this data in the…

Quantitative Methods · Quantitative Biology 2019-01-11 Sahil D. Shah , Rosemary Braun

In this paper, we explore the reduction of functionality in a complex system as a consequence of cumulative random damage and imperfect reparation, a phenomenon modeled as a dynamical process on networks. We analyze the global…

Statistical Mechanics · Physics 2021-06-07 L. K. Eraso-Hernandez , A. P. Riascos , T. M. Michelitsch , J. Wang-Michelitsch

Multi-omics data offer unprecedented insights into complex biological systems, yet their high dimensionality, sparsity, and intricate interactions pose significant analytical challenges. Network-based approaches have advanced multi-omics…

Competition is ubiquitous in many complex biological, social, and technological systems, playing an integral role in the evolutionary dynamics of the systems. It is often useful to determine the dominance hierarchy or the rankings of the…

Physics and Society · Physics 2019-01-09 Seungkyu Shin , Sebastian E. Ahnert , Juyong Park